197553

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4801021..4801382 Replicon chromosome
Accession NZ_CP072263
Organism Xanthomonas citri pv. glycines CFBP 2526

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag XcgCFBP2526_RS20875 Protein ID WP_005914328.1
Coordinates 4801021..4801155 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag XcgCFBP2526_RS20880 Protein ID WP_003486606.1
Coordinates 4801230..4801382 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XcgCFBP2526_RS20855 (XcgCFBP2526_20855) 4796172..4797863 - 1692 WP_029829576.1 M28 family metallopeptidase -
XcgCFBP2526_RS20860 (XcgCFBP2526_20860) 4798055..4798999 - 945 WP_026007158.1 MBL fold metallo-hydrolase -
XcgCFBP2526_RS20865 (XcgCFBP2526_20865) 4799128..4800417 - 1290 WP_016850773.1 tryptophan--tRNA ligase -
XcgCFBP2526_RS20870 (XcgCFBP2526_20870) 4800585..4800794 - 210 WP_003486601.1 CsbD family protein -
XcgCFBP2526_RS20875 (XcgCFBP2526_20875) 4801021..4801155 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
XcgCFBP2526_RS20880 (XcgCFBP2526_20880) 4801230..4801382 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
XcgCFBP2526_RS20885 (XcgCFBP2526_20885) 4801489..4802412 - 924 WP_003486608.1 arginase -
XcgCFBP2526_RS20890 (XcgCFBP2526_20890) 4802733..4803185 + 453 WP_003486611.1 roadblock/LC7 domain-containing protein -
XcgCFBP2526_RS20895 (XcgCFBP2526_20895) 4803249..4803608 + 360 WP_003486613.1 hypothetical protein -
XcgCFBP2526_RS20900 (XcgCFBP2526_20900) 4803705..4804622 + 918 WP_016850774.1 hypothetical protein -
XcgCFBP2526_RS20905 (XcgCFBP2526_20905) 4804619..4805161 + 543 WP_003486615.1 GTPase -
XcgCFBP2526_RS20910 (XcgCFBP2526_20910) 4805599..4806282 + 684 WP_011052674.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T197553 WP_005914328.1 NZ_CP072263:c4801155-4801021 [Xanthomonas citri pv. glycines CFBP 2526]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T197553 NZ_CP096242:4154560-4154778 [Klebsiella pneumoniae subsp. pneumoniae]
ATGTCTGATAAGCCATTAACTAAAACAGACTATTTGATGCGCTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGCGT
CATTGAAAAAAATAAATATGAACTGTCTGATAATGAGCTGGCGGTATTTTACTCAGCTGCCGACCATCGTCTGGCGGAAC
TGACCATGAATAAGCTATACGATAAAATCCCGACTTCTGTCTGGAAATTTATCCGCTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT197553 WP_003486606.1 NZ_CP072263:c4801382-4801230 [Xanthomonas citri pv. glycines CFBP 2526]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT197553 NZ_CP096242:4154159-4154533 [Klebsiella pneumoniae subsp. pneumoniae]
ATGGACGAATACTCGCCAAAAAGACATGATATTGCACAGCTACGCTTTCTCTGCGAAACGCTGTATCATGACTGCCTTGC
AAACCTGGAAGAGAGCAACCATGGCTGGGTCAACGACCCGACGTCGGCTGTCAATCTCCAGTTAAATGAATTGATCGAGC
ACATTGCCACATTCGCTCTTAATTATAAAATTAAGTATGCAGAGGATAATAAGCTGATCGCTCAGGTTGACGAATATCTG
GACGACACTTTTACGTTGTTCAGTAACTACGGCATTAACTCTACGGATTTGCAAAAGTGGAAAAAATCCGGTAACCGACT
ATTTCGTTGCTTTGTCAACGCCAGCCGGGAAAACCCGGCCAGTCTATCGTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References