Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 691646..692208 Replicon chromosome
Accession NZ_CP072203
Organism Gordonia polyisoprenivorans strain R9

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag J6U32_RS03195 Protein ID WP_208793516.1
Coordinates 691646..691936 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag J6U32_RS03200 Protein ID WP_208793517.1
Coordinates 691933..692208 (-) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J6U32_RS03180 (J6U32_03180) 687167..688768 - 1602 WP_208793513.1 class I adenylate-forming enzyme family protein -
J6U32_RS03185 (J6U32_03185) 688765..689403 - 639 WP_208793514.1 nitroreductase family protein -
J6U32_RS03190 (J6U32_03190) 689547..691496 + 1950 WP_208793515.1 NAD(P)/FAD-dependent oxidoreductase -
J6U32_RS03195 (J6U32_03195) 691646..691936 - 291 WP_208793516.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
J6U32_RS03200 (J6U32_03200) 691933..692208 - 276 WP_208793517.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
J6U32_RS03205 (J6U32_03205) 692393..693724 + 1332 WP_208795932.1 SWIM zinc finger family protein -
J6U32_RS03210 (J6U32_03210) 693721..695199 + 1479 WP_208793518.1 DUF5691 domain-containing protein -
J6U32_RS03215 (J6U32_03215) 695196..696287 + 1092 WP_208793519.1 AAA family ATPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(14-94)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10914.44 Da        Isoelectric Point: 9.0435

>T197516 WP_208793516.1 NZ_CP072203:c691936-691646 [Gordonia polyisoprenivorans]
MSEDPGCSPDPYRVEVASPARRDLERLPSRIVHAVIEFISGPLAENPHRLGKPLRDQLEGLRSARRGDYRILLRIDDSGH
TIIIVRIDHRAHAYRA

Download         Length: 291 bp

>T197516 NZ_CP096231:c54669-54358 [Klebsiella pneumoniae subsp. pneumoniae]
ATGCACGTAATTTCAAAAGAGCCTTTTGAGGAAGCGGCAAAGCGATATCCCAACGATTCGTTAGCCATTCGGGCGTTGTA
CCGCTTAGTGCGCGAGACGGACTTCTCTTCTCCAGCTGAGATGCTAACTCTGATACCGAGCCTGGATAATTTTAAGTACA
GGAATAAGTGGTGGGTTTTGGATGTAGGGGGCAACAACTTAAGGGTTATCGCCTATATCAATTTCGTAAATAAGCGCTTC
TACGTGAAGCACATCGCAACCCACGCTGATTACGACAAGTTGACCCGCTATTACAGGGAGAACAAAGAATGA

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 9779.87 Da        Isoelectric Point: 4.4802

>AT197516 WP_208793517.1 NZ_CP072203:c692208-691933 [Gordonia polyisoprenivorans]
MTTVPLGEAKDKLSALIDSAATTHDIITITKHGKPAAVLMSADDLESLHETIYWLSRSGTRDDMATADAEYSAGHTTSLE
DLRAEHGMPPE

Download         Length: 276 bp

>AT197516 NZ_CP096231:c54361-53942 [Klebsiella pneumoniae subsp. pneumoniae]
ATGATTACCGACACTGCAAAAGCCATTGAAGCAACCAAACAACTCGTAGCTGCCGTCCCCTTCCTAGGGGGCAGTTCTTC
CGAGAGCGATTACCGCGAAGCGATGGAGCTGGTGGATTATCTGATCGAGAACGACGACGAGAACCCACTTATTGACTTCC
TGGCGAGTAAGATTGCCGACTATGAAGATAACAGCCCTCGTTTCGCTGAGTTCAACAAAGCTATTGCTGAAATACCAGTC
GGCGTTGCACTTCTGCGAACCCTGATTGACCAGCACAAGCTGTCTTATTCAGACCTTAAGGATGAGATCGGATCTAAATC
ATTGGTCAGCCAAATCCTGTCAGGGCAGCGCTCTTTGACCATCACTCACATAAAAGCTCTTTCCGCGCGCTTCGGTGTAA
AACCTGAGTGGTTCCTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References