Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3600331..3600476 Replicon chromosome
Accession NZ_CP072200
Organism Klebsiella pneumoniae strain B5055

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3600338..3600440 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3600331..3600476 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J6T75_RS17905 (J6T75_17840) 3595863..3597296 + 1434 WP_016529029.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
J6T75_RS17910 (J6T75_17845) 3597412..3597651 + 240 WP_002911393.1 YebV family protein -
J6T75_RS17915 (J6T75_17850) 3597749..3597940 + 192 WP_002911395.1 YebW family protein -
J6T75_RS17920 (J6T75_17855) 3597937..3598590 - 654 WP_016529030.1 protein-serine/threonine phosphatase -
J6T75_RS17925 (J6T75_17860) 3598747..3599715 + 969 WP_004151446.1 VirK/YbjX family protein -
J6T75_RS17930 (J6T75_17865) 3599820..3599963 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3600331..3600476 + 146 - - Antitoxin
- 3600338..3600440 - 103 - - Toxin
J6T75_RS17935 (J6T75_17870) 3600599..3600937 - 339 WP_016529031.1 YebY family protein -
J6T75_RS17940 (J6T75_17875) 3600954..3601823 - 870 WP_004184661.1 copper homeostasis membrane protein CopD -
J6T75_RS17945 (J6T75_17880) 3601827..3602201 - 375 WP_016529032.1 CopC domain-containing protein YobA -
J6T75_RS17950 (J6T75_17885) 3602314..3602544 + 231 WP_002911406.1 DNA polymerase III subunit theta -
J6T75_RS17955 (J6T75_17890) 3602623..3603282 + 660 WP_002911407.1 exodeoxyribonuclease X -
J6T75_RS17960 (J6T75_17895) 3603286..3605346 - 2061 WP_004148850.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T197499 NZ_CP072200:c3600440-3600338 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT197499 NZ_CP072200:3600331-3600476 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References