Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 134102..134868 Replicon plasmid pTiAB2_73
Accession NZ_CP072175
Organism Rhizobium sp. AB2/73

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag J5284_RS31540 Protein ID WP_209159800.1
Coordinates 134386..134868 (+) Length 161 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag J5284_RS31535 Protein ID WP_209159801.1
Coordinates 134102..134386 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J5284_RS31520 (J5284_31520) 129617..130666 + 1050 WP_209159804.1 P-type DNA transfer ATPase VirB11 -
J5284_RS31525 (J5284_31525) 130635..133421 + 2787 WP_209159803.1 type IV secretory system conjugative DNA transfer family protein -
J5284_RS31530 (J5284_31530) 133516..133860 + 345 WP_209159802.1 hypothetical protein -
J5284_RS31535 (J5284_31535) 134102..134386 + 285 WP_209159801.1 DUF1778 domain-containing protein Antitoxin
J5284_RS31540 (J5284_31540) 134386..134868 + 483 WP_209159800.1 GNAT family N-acetyltransferase Toxin
J5284_RS31545 (J5284_31545) 134930..136276 - 1347 WP_209159799.1 hypothetical protein -
J5284_RS31550 (J5284_31550) 136586..136924 + 339 WP_209159798.1 helix-turn-helix domain-containing protein -
J5284_RS31555 (J5284_31555) 136959..137492 - 534 WP_229002329.1 hypothetical protein -
J5284_RS31560 (J5284_31560) 137523..137894 - 372 WP_209159796.1 hypothetical protein -
J5284_RS31565 (J5284_31565) 137903..138217 - 315 WP_209159795.1 hypothetical protein -
J5284_RS31570 (J5284_31570) 138218..138850 - 633 WP_209159794.1 thermonuclease family protein -
J5284_RS31575 (J5284_31575) 138847..139473 - 627 WP_209159793.1 thermonuclease family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..605541 605541


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(41-141)

Antitoxin

Vibrio phage ICP1, Orf50

(15-86)


Sequences

Toxin        


Download         Length: 161 a.a.        Molecular weight: 17320.86 Da        Isoelectric Point: 7.2427

>T197470 WP_209159800.1 NZ_CP072175:134386-134868 [Rhizobium sp. AB2/73]
MLSAPALLEEAHDLDLFQSGNDTLDEWLRRRARPNQVSGASRTYVVAEGQRVVGYYCLASGALDLADAPGSVRRNMPDPI
PMAVLGRLAIDRGWQGRGLGAALLQDAVLRTSQAASIMGIRGLLVHAISEDAKAFYEHYGFLCSPNQPMTLVLSLKIRTG

Download         Length: 483 bp

>T197470 NZ_CP096201:2093097-2093199 [Kluyvera ascorbata]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAAAACA
GGAATCGTTTTCGGTCTCTTTTT

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10723.12 Da        Isoelectric Point: 7.3189

>AT197470 WP_209159801.1 NZ_CP072175:134102-134386 [Rhizobium sp. AB2/73]
MATKSLTDSHAKPVHLRIREDVRKVIDRAASIRGKSRTDFMIDAAYRAAEDALLDQTLVRVDEDSYRHFLSVLDQPPNGE
GFERLMNAPKPWQS

Download         Length: 285 bp

>AT197470 NZ_CP096201:c2093205-2093061 [Kluyvera ascorbata]
ACAGATAAAAAGAGACCGAAAACGATTCCTGTTTTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCTTTATAAGAATAGATGACCGTGACAGGTTTTCCAGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References