Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 682692..683245 Replicon plasmid unnamed2
Accession NZ_CP072174
Organism Rhizobium sp. AB2/73

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag J5284_RS29025 Protein ID WP_069614884.1
Coordinates 682692..682985 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag J5284_RS29030 Protein ID WP_113367594.1
Coordinates 682973..683245 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J5284_RS29000 (J5284_29000) 678326..679390 + 1065 WP_069614888.1 ABC transporter ATP-binding protein -
J5284_RS29005 (J5284_29005) 679387..680244 + 858 WP_113367595.1 ABC transporter permease -
J5284_RS29010 (J5284_29010) 680244..681026 + 783 WP_069614886.1 ABC transporter permease -
J5284_RS29015 (J5284_29015) 681216..682409 - 1194 WP_069614885.1 S53 family peptidase -
J5284_RS29020 (J5284_29020) 682409..682567 - 159 Protein_648 hypothetical protein -
J5284_RS29025 (J5284_29025) 682692..682985 - 294 WP_069614884.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
J5284_RS29030 (J5284_29030) 682973..683245 - 273 WP_113367594.1 CopG family ribbon-helix-helix protein Antitoxin
J5284_RS29035 (J5284_29035) 683702..684286 - 585 WP_069614882.1 TetR/AcrR family transcriptional regulator -
J5284_RS29040 (J5284_29040) 684418..685293 + 876 WP_229002237.1 alpha/beta hydrolase -
J5284_RS29045 (J5284_29045) 685648..686175 - 528 WP_069614881.1 DUF4269 domain-containing protein -
J5284_RS29050 (J5284_29050) 686559..686777 + 219 WP_069614879.1 hypothetical protein -
J5284_RS29055 (J5284_29055) 687327..688163 + 837 WP_113367593.1 alpha/beta hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..1068678 1068678


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-95)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-40)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10716.32 Da        Isoelectric Point: 8.0341

>T197468 WP_069614884.1 NZ_CP072174:c682985-682692 [Rhizobium sp. AB2/73]
VPRVIVTEGAAQGLERCRRFLAAKAPTAASRAGRAIERQFLLLESTPLIGRPLPDDAQLRELVIPFGDSGYVALYRHEPD
GDIVFVLAFRHQKEAGY

Download         Length: 294 bp

>T197468 NZ_CP096201:c1197650-1197321 [Kluyvera ascorbata]
ATGAAAACTTTACCTGCAACAACTCCGCAGGCGGCGAAGCTATGTCTGCCGCCCGTGGCCGTCTGGCAAATGTTACTGAC
ACGCCTGCTGGAAACGCACTATGGCCTGACACTGAACGACACGCCATTCAGTGATGAAACTGTTATTAAGGAACATATTG
ATGCCGGGATCACCCTGGCCGATGCAGTCAACTTTCTGGTGGAAAAATACGAACTGGTTCGTATCGACAGGAATGGATTT
TCGTGGCAAGAACAAACCCCGTATATTTCCGTAGTGGATATTCTGCGAGCAAGGCGCTCTACCGGCTTGCTAAAAAATAA
CGTGAAATAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10570.65 Da        Isoelectric Point: 4.7301

>AT197468 WP_113367594.1 NZ_CP072174:c683245-682973 [Rhizobium sp. AB2/73]
MATSLKIDDELKNRVQNLASQRRRSAHWIILEAIQQYVEREEARENFKQEALASWAAYQETGRHLTGQEVRTWLDTWGTD
AEETVPECHE

Download         Length: 273 bp

>AT197468 NZ_CP096201:c1197988-1197671 [Kluyvera ascorbata]
ATGAGCAAAATCACATGGGGTCTGCAGCGAAATATCACGCCACACCTGGGAGCCCGTCTGGTGCAGGAGGGGAACCGGCT
GCATTATCTGGCTGATCGGGCCAGTATCACCGGTAAGATCAGTGACGCCGAATGTCTTAAGCTGGATGTGGCATTTCCGC
ATTTTATCAGTCAGATGGAATTGATGCTGACCACCGGTGAAATGAACCCTTGCCATGCCCACTGCGTCATCCTGTATCAC
AACGGTTTCACCTGCGAAGCCGATACCCTTGGCAGTTGCGGCTACGTATACGTCGCCGTTTATCCCACTCAGCGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References