Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-parD/RelE-RHH
Location 766700..767283 Replicon chromosome
Accession NZ_CP072172
Organism Rhizobium sp. AB2/73

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag J5284_RS03900 Protein ID WP_113366807.1
Coordinates 766987..767283 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag J5284_RS03895 Protein ID WP_113366806.1
Coordinates 766700..766990 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J5284_RS03875 (J5284_03875) 761977..762999 + 1023 WP_112722851.1 glucokinase -
J5284_RS03880 (J5284_03880) 763211..765004 + 1794 WP_112722850.1 ABC transporter ATP-binding protein -
J5284_RS03885 (J5284_03885) 765019..765843 + 825 WP_113366805.1 4-hydroxy-tetrahydrodipicolinate reductase -
J5284_RS03890 (J5284_03890) 765965..766600 + 636 WP_112722848.1 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase -
J5284_RS03895 (J5284_03895) 766700..766990 + 291 WP_113366806.1 hypothetical protein Antitoxin
J5284_RS03900 (J5284_03900) 766987..767283 + 297 WP_113366807.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
J5284_RS03905 (J5284_03905) 767291..768025 - 735 WP_113366808.1 phosphonate metabolism transcriptional regulator PhnF -
J5284_RS03910 (J5284_03910) 768127..768603 + 477 WP_112722845.1 phosphonate C-P lyase system protein PhnG -
J5284_RS03915 (J5284_03915) 768603..769229 + 627 WP_113366809.1 phosphonate C-P lyase system protein PhnH -
J5284_RS03920 (J5284_03920) 769233..770342 + 1110 WP_113366810.1 carbon-phosphorus lyase complex subunit PhnI -
J5284_RS03925 (J5284_03925) 770339..771250 + 912 WP_069610920.1 alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase PhnJ -
J5284_RS03930 (J5284_03930) 771247..772023 + 777 WP_113366811.1 phosphonate C-P lyase system protein PhnK -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-89)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11175.92 Da        Isoelectric Point: 9.5301

>T197459 WP_113366807.1 NZ_CP072172:766987-767283 [Rhizobium sp. AB2/73]
VKLAWTPEARADRRAIYTYIEAENATAALALDELLAKRSKQLITHPMTGRPGRVSGTRELVVHRNYLLVYDLADEMVRII
RILHAAQQWPPSDFQPIP

Download         Length: 297 bp

>T197459 NZ_CP096200:c1024394-1024104 [Vibrio sinaloensis]
ATGACCTATAAACTCGACTTTAAAAAGAGCGCACTCAAAGAGTGGAAAAAGCTTGGCTCTACTCTGCAACAACAATTTAA
GAAAAAGCTAATCGAGCGCTTGGATAACCCACATGTTCCGGCTTCAAAACTTTCTGGAGCTGACAACATGTATAAAATTA
AACTCCGTCAATCGGGCTACCGTCTCGTCTACAAAGTTGAAGACGATGTAATCATTGTAACCGTCTTAGCAGTCGGAAAA
CGCGAACGTAGCGATGTTTACCGTAAAGCTATGAAAAGATTAGATGATTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10872.98 Da        Isoelectric Point: 4.6812

>AT197459 WP_113366806.1 NZ_CP072172:766700-766990 [Rhizobium sp. AB2/73]
MTDATFTFRVEEELKAAFSEAAKAHDQTGAQLLRAFMRDYVRRQQDAAEYDIWFRQQVQAGLTSANAGNLIPDDDVDAEF
AALREETRRKLSGRSS

Download         Length: 291 bp

>AT197459 NZ_CP096200:c1024632-1024384 [Vibrio sinaloensis]
ATGACCACTAGAATTTTAGCCGATGTTGCTGCAAGCATTACTGAGTTGAAAGCTAACCCTATGAAAGTTGCAACTAGTGC
TTATGGCGAACCTGTTGCTGTACTGAACCGAAATGAACCAGCATTTTATTGCGTACCTGCAGAAGCGTACGAAATGATGA
TGGACAGACTCGAAGATCTTGAACTACTAGCTATTGCGAAAGAGCGTGAATCTGAAGAGAGCATTTCGGTAAATATTGAT
GACCTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References