Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 2071574..2072205 Replicon chromosome
Accession NZ_CP072167
Organism Agrobacterium larrymoorei strain AF3.44

Toxin (Protein)


Gene name vapC Uniprot ID A0A4D7DKT4
Locus tag J5285_RS09850 Protein ID WP_027675859.1
Coordinates 2071807..2072205 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A4D7DRW1
Locus tag J5285_RS09845 Protein ID WP_027675860.1
Coordinates 2071574..2071807 (+) Length 78 a.a.

Genomic Context

J5285_RS09825J5285_RS09830J5285_RS09835J5285_RS09840J5285_RS09845J5285_RS09850J5285_RS09855J5285_RS09860J5285_RS09865
Location: 2067942..2069159 (1218 bp)
Type: Others
Protein ID: WP_027675864.1
Location: 2069217..2070104 (888 bp)
Type: Others
Protein ID: WP_027675863.1
Location: 2070110..2070781 (672 bp)
Type: Others
Protein ID: WP_027675862.1
Location: 2070830..2071489 (660 bp)
Type: Others
Protein ID: WP_084631681.1
Location: 2071574..2071807 (234 bp)
Type: Antitoxin
Protein ID: WP_027675860.1
Location: 2071807..2072205 (399 bp)
Type: Toxin
Protein ID: WP_027675859.1
Location: 2072222..2073052 (831 bp)
Type: Others
Protein ID: WP_027675858.1
Location: 2073052..2074068 (1017 bp)
Type: Others
Protein ID: WP_027675857.1
Location: 2074174..2075115 (942 bp)
Type: Others
Protein ID: WP_027675856.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
J5285_RS09825 (J5285_09830)2067942..2069159+1218WP_027675864.1endolytic transglycosylase MltG-
J5285_RS09830 (J5285_09835)2069217..2070104+888WP_027675863.1YicC/YloC family endoribonuclease-
J5285_RS09835 (J5285_09840)2070110..2070781+672WP_027675862.1guanylate kinase-
J5285_RS09840 (J5285_09845)2070830..2071489+660WP_084631681.1glycerol-3-phosphate 1-O-acyltransferase PlsY-
J5285_RS09845 (J5285_09850)2071574..2071807+234WP_027675860.1AbrB/MazE/SpoVT family DNA-binding domain-containing proteinAntitoxin
J5285_RS09850 (J5285_09855)2071807..2072205+399WP_027675859.1type II toxin-antitoxin system VapC family toxinToxin
J5285_RS09855 (J5285_09860)2072222..2073052-831WP_027675858.116S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA-
J5285_RS09860 (J5285_09865)2073052..2074068-1017WP_027675857.14-hydroxythreonine-4-phosphate dehydrogenase PdxA-
J5285_RS09865 (J5285_09870)2074174..2075115-942WP_027675856.1peptidylprolyl isomerase-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic island-acpXL2061494..207220510711


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(7-56)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14862.17 Da        Isoelectric Point: 6.8525

>T197453 WP_027675859.1 NZ_CP072167:2071807-2072205 [Agrobacterium larrymoorei]
MLTYMLDTNICIYVMKTYPPELREKFNALAEQLCISSITLGELYYGAEKSARRTDNIHAIDNFVARLEVLPFADKAAAHY
GQIRAELTKAGTPCGVHDMQIGGHARSEGLIVVTNNMREFVRMPGLRVENWV

Download         Length: 399 bp

>T197453 NZ_CP096187:c2847515-2847412 [Enterobacter roggenkampii]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8712.93 Da        Isoelectric Point: 5.8152

>AT197453 WP_027675860.1 NZ_CP072167:2071574-2071807 [Agrobacterium larrymoorei]
MATSTVFISNRSQAVRLPKAVAFPEDVHKVDVLKVGLTRIIVPQGSRWDDLFLSGPKATQDFLERREEPALDERESF

Download         Length: 234 bp

>AT197453 NZ_CP096187:2847405-2847550 [Enterobacter roggenkampii]
AACAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTTTAAGAATAGATGACGACGCCAGGTTTTCCAGT

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A4D7DKT4

Antitoxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A4D7DRW1

References