Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-dinJ/YafQ-RelB
Location 1875747..1876350 Replicon chromosome
Accession NZ_CP072167
Organism Agrobacterium larrymoorei strain AF3.44

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag J5285_RS08875 Protein ID WP_027676894.1
Coordinates 1876123..1876350 (+) Length 76 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID A0A4D7DQ05
Locus tag J5285_RS08870 Protein ID WP_027676893.1
Coordinates 1875747..1876022 (+) Length 92 a.a.

Genomic Context

J5285_RS08850J5285_RS08870J5285_RS08875J5285_RS08900J5285_RS08845J5285_RS08855J5285_RS08860J5285_RS08865J5285_RS08880J5285_RS08885J5285_RS08890J5285_RS08895
Location: 1872009..1872440 (432 bp)
Type: Others
Protein ID: WP_027676889.1
Location: 1875747..1876022 (276 bp)
Type: Antitoxin
Protein ID: WP_027676893.1
Location: 1876123..1876350 (228 bp)
Type: Toxin
Protein ID: WP_027676894.1
Location: 1880511..1881155 (645 bp)
Type: Others
Protein ID: WP_027676900.1
Location: 1870789..1871889 (1101 bp)
Type: Others
Protein ID: WP_027676888.1
Location: 1872447..1872647 (201 bp)
Type: Others
Protein ID: WP_027676890.1
Location: 1872666..1873085 (420 bp)
Type: Others
Protein ID: WP_027676891.1
Location: 1873082..1875601 (2520 bp)
Type: Others
Protein ID: WP_027676892.1
Location: 1876355..1877167 (813 bp)
Type: Others
Protein ID: WP_037171690.1
Location: 1877343..1878806 (1464 bp)
Type: Others
Protein ID: WP_027676896.1
Location: 1878881..1879594 (714 bp)
Type: Others
Protein ID: WP_084631815.1
Location: 1879818..1880231 (414 bp)
Type: Others
Protein ID: WP_027676899.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
J5285_RS08845 (J5285_08850)1870789..1871889-1101WP_027676888.1saccharopine dehydrogenase family protein-
J5285_RS08850 (J5285_08855)1872009..1872440+432WP_027676889.1Lrp/AsnC family transcriptional regulator-
J5285_RS08855 (J5285_08860)1872447..1872647-201WP_027676890.1heavy-metal-associated domain-containing protein-
J5285_RS08860 (J5285_08865)1872666..1873085-420WP_027676891.1Cu(I)-responsive transcriptional regulator-
J5285_RS08865 (J5285_08870)1873082..1875601-2520WP_027676892.1heavy metal translocating P-type ATPase-
J5285_RS08870 (J5285_08875)1875747..1876022+276WP_027676893.1type II toxin-antitoxin system RelB/DinJ family antitoxinAntitoxin
J5285_RS08875 (J5285_08880)1876123..1876350+228WP_027676894.1type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE familyToxin
J5285_RS08880 (J5285_08885)1876355..1877167-813WP_037171690.1class D beta-lactamase-
J5285_RS08885 (J5285_08890)1877343..1878806-1464WP_027676896.1YdiU family protein-
J5285_RS08890 (J5285_08895)1878881..1879594-714WP_084631815.1YcxB family protein-
J5285_RS08895 (J5285_08900)1879818..1880231-414WP_027676899.1hypothetical protein-
J5285_RS08900 (J5285_08905)1880511..1881155+645WP_027676900.1suppressor of fused domain protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic island--1865756..188023114475


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(10-75)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-86)


Sequences

Toxin        


Download         Length: 76 a.a.        Molecular weight: 8736.95 Da        Isoelectric Point: 4.9491

>T197451 WP_027676894.1 NZ_CP072167:1876123-1876350 [Agrobacterium larrymoorei]
MNPVVTTWWLKEVMLLSIANDAPLPLNFRDHELTGDWRDHRECHIGGDFLLIYTLDDAQNLIVFTRAGTHSELFR

Download         Length: 228 bp

>T197451 NZ_CP096187:c1150882-1150520 [Enterobacter roggenkampii]
ATGTGGAACGTCGAGACAACGGACAGATTTGACGACTGGTTCTTTGAACAAACAACAGCATTAAAAGAAGATGTGCTGGC
GACGATGCATATTCTTGCTGAATTTGGCCCAACCCTGGGGCGACCATACGTAGACACCGTGAAGGATTCAGCCTATGCGA
ACATGAAAGAGTTACGTATTCAGCATGCGGGTAATCCCATCAGAGCCTTTTTTGCCTTTGATCCTGACCGTAAGGCAATT
GTGCTCTGTGCTGGAGACAAAACCGGTTGCAATCAAAAACGGTTTTATAACGAAATGATCGCGCTGGCTGACGTTGAATA
CAGCAGACATCTGGCGGATAAGGAGGCCATATGGCAACGCTAA

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10131.65 Da        Isoelectric Point: 5.2072

>AT197451 WP_027676893.1 NZ_CP072167:1875747-1876022 [Agrobacterium larrymoorei]
MTANAYVRARIDQEIKDDATAVLDSLGLTVSDVMRMMLTRIAREKALPIELTRPNAETLAAMEEARAIARAKRERFRSAE
EIIDALDGGKQ

Download         Length: 276 bp

>AT197451 NZ_CP096187:c1150532-1150233 [Enterobacter roggenkampii]
ATGGCAACGCTAAAAGAACTCATAGCACAACAGAGCGCGGAAAGTCAGGAGCGTATAGCGGCTAAAGTTGAAGTGATGCG
CAGAATTGTTGCCCTGAACCAGCTGCGGGAAGAGCTCAATATTTCCCAGACAGAACTGGCCGCAGCAATGGGGGTAAAAC
AACCCACTTTGGCAAAAATCGAACAGCCGGGAAACGATCCCCGGCTTTCAACACTCAAACGCTATGTCAGTGCGCTCGGC
GGTGAAATGAGCATTGATGTGACGCTACCGAATGGGAAACGGATAGCGTTTCAGATTTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A4D7DQ05

References