Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relB-parE/ParE-RHH |
Location | 158489..159054 | Replicon | chromosome |
Accession | NZ_CP072167 | ||
Organism | Agrobacterium larrymoorei strain AF3.44 |
Toxin (Protein)
Gene name | parE | Uniprot ID | A0A4D7DZI7 |
Locus tag | J5285_RS00695 | Protein ID | WP_027674231.1 |
Coordinates | 158489..158782 (-) | Length | 98 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | A0A4D7DSM4 |
Locus tag | J5285_RS00700 | Protein ID | WP_027674230.1 |
Coordinates | 158770..159054 (-) | Length | 95 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
J5285_RS00680 (J5285_00680) | 153847..155703 | - | 1857 | WP_027674234.1 | ABC transporter ATP-binding protein | - |
J5285_RS00685 (J5285_00685) | 156118..156579 | + | 462 | WP_027674233.1 | tRNA (cytidine(34)-2'-O)-methyltransferase | - |
J5285_RS00690 (J5285_00690) | 156811..158463 | + | 1653 | WP_027674232.1 | Na/Pi cotransporter family protein | - |
J5285_RS00695 (J5285_00695) | 158489..158782 | - | 294 | WP_027674231.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
J5285_RS00700 (J5285_00700) | 158770..159054 | - | 285 | WP_027674230.1 | ribbon-helix-helix protein, CopG family | Antitoxin |
J5285_RS00705 (J5285_00705) | 159132..159407 | - | 276 | WP_027674229.1 | hypothetical protein | - |
J5285_RS00710 (J5285_00710) | 159533..160444 | + | 912 | WP_027674228.1 | oxygen-dependent coproporphyrinogen oxidase | - |
J5285_RS00715 (J5285_00715) | 160611..160877 | + | 267 | WP_027674227.1 | hypothetical protein | - |
J5285_RS00720 (J5285_00720) | 161029..161217 | + | 189 | WP_027674226.1 | DUF1059 domain-containing protein | - |
J5285_RS00725 (J5285_00725) | 161447..162694 | - | 1248 | WP_027674225.1 | CCA tRNA nucleotidyltransferase | - |
J5285_RS00730 (J5285_00730) | 162691..163338 | - | 648 | WP_027674224.1 | CoA pyrophosphatase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 98 a.a. Molecular weight: 11037.89 Da Isoelectric Point: 9.5450
>T197444 WP_027674231.1 NZ_CP072167:c158782-158489 [Agrobacterium larrymoorei]
MPQLIWTPEALRDVQRCYRFLAPKNPDAASRAIKSIREKMRMIVTHPAIGRPVDKMAPEFRELLIPFGESGYVALYRLDG
DLAVVLAVRHQNEAGYT
MPQLIWTPEALRDVQRCYRFLAPKNPDAASRAIKSIREKMRMIVTHPAIGRPVDKMAPEFRELLIPFGESGYVALYRLDG
DLAVVLAVRHQNEAGYT
Download Length: 294 bp
>T197444 NZ_CP096184:289942-290307 [Demequina sp. TMPB413]
ATGAGGCGCGGCGAGATCAGGTGGGTAGCGCTCGATGCCGGCGCCGACGCGGAGGCACGTTCGCGCGCTCAGCGCCCCGC
GGTGATCGTCTCTAACGACGGCGCCAACACGGCGGCCGCACGGCGCGGTTCTGGAGCTGTCACTGTGGTGCCCTTGACCA
CGTCCGACGCGCCCGCGAAGCCCTTCCAGGTAGCACTGGCCGCCGGCGTCGGCGGTCTGCCCAGGGCAGCCAAAGCCATG
GCCGAGCAAGTGCGCACCGTCTCTGCGGGACGCGTCGGCCCGAGCATCGGCATGCTGTCGCTGAGCGACGTAGCCAAGAT
CGATGACGCCTTGCGGCTACACCTCGGCCTCGATCGCGGGCGTTAG
ATGAGGCGCGGCGAGATCAGGTGGGTAGCGCTCGATGCCGGCGCCGACGCGGAGGCACGTTCGCGCGCTCAGCGCCCCGC
GGTGATCGTCTCTAACGACGGCGCCAACACGGCGGCCGCACGGCGCGGTTCTGGAGCTGTCACTGTGGTGCCCTTGACCA
CGTCCGACGCGCCCGCGAAGCCCTTCCAGGTAGCACTGGCCGCCGGCGTCGGCGGTCTGCCCAGGGCAGCCAAAGCCATG
GCCGAGCAAGTGCGCACCGTCTCTGCGGGACGCGTCGGCCCGAGCATCGGCATGCTGTCGCTGAGCGACGTAGCCAAGAT
CGATGACGCCTTGCGGCTACACCTCGGCCTCGATCGCGGGCGTTAG
Antitoxin
Download Length: 95 a.a. Molecular weight: 10729.96 Da Isoelectric Point: 6.2152
>AT197444 WP_027674230.1 NZ_CP072167:c159054-158770 [Agrobacterium larrymoorei]
MPGPHPVAVKLDPEVHARMRKLAQAQHRSTHYLMREAIAQYVEREEKRAAFRQDALEAWSAYQASGSHLNQTEADEWLAK
LEAGQDVEPPECHN
MPGPHPVAVKLDPEVHARMRKLAQAQHRSTHYLMREAIAQYVEREEKRAAFRQDALEAWSAYQASGSHLNQTEADEWLAK
LEAGQDVEPPECHN
Download Length: 285 bp
>AT197444 NZ_CP096184:289739-289942 [Demequina sp. TMPB413]
GTGAAGCTCAGCATCAGCTTGACCGACGATGACGTCGCCTTGATCGATCAGTTCGCGGCCGCAGGTGACTACCCTTCCCG
CTCCGCAGTCATTCAGCACGCGCTCGCCAGGCTCCGCGCCCAGGGCCTCCACGGCGACTACGCCGACGCCTGGACGGAGT
TCTCGGATGGCGGCGACGCAGGCCGCTGGGAGGCGTCGTCCTGA
GTGAAGCTCAGCATCAGCTTGACCGACGATGACGTCGCCTTGATCGATCAGTTCGCGGCCGCAGGTGACTACCCTTCCCG
CTCCGCAGTCATTCAGCACGCGCTCGCCAGGCTCCGCGCCCAGGGCCTCCACGGCGACTACGCCGACGCCTGGACGGAGT
TCTCGGATGGCGGCGACGCAGGCCGCTGGGAGGCGTCGTCCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A4D7DZI7 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A4D7DSM4 |