Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | hipBA/HipA-couple_hipB |
| Location | 1422185..1423674 | Replicon | chromosome |
| Accession | NZ_CP072163 | ||
| Organism | Rhizobium sp. B21/90 | ||
Toxin (Protein)
| Gene name | HipA1 | Uniprot ID | - |
| Locus tag | J5278_RS24565 | Protein ID | WP_209186796.1 |
| Coordinates | 1422412..1423674 (+) | Length | 421 a.a. |
Antitoxin (Protein)
| Gene name | HipB1 | Uniprot ID | - |
| Locus tag | J5278_RS24560 | Protein ID | WP_209186795.1 |
| Coordinates | 1422185..1422415 (+) | Length | 77 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| J5278_RS24525 (J5278_24545) | 1417488..1417736 | - | 249 | WP_209186791.1 | hypothetical protein | - |
| J5278_RS24530 (J5278_24550) | 1417767..1418114 | - | 348 | WP_247749904.1 | hypothetical protein | - |
| J5278_RS24535 (J5278_24555) | 1418403..1418891 | - | 489 | WP_209186792.1 | nuclear transport factor 2 family protein | - |
| J5278_RS31230 | 1419288..1419507 | + | 220 | Protein_1265 | IS66 family transposase | - |
| J5278_RS24545 (J5278_24565) | 1419533..1419760 | - | 228 | WP_209186807.1 | DUF6429 family protein | - |
| J5278_RS24550 (J5278_24570) | 1419964..1421595 | - | 1632 | WP_209186808.1 | FAD-dependent oxidoreductase | - |
| J5278_RS24555 (J5278_24575) | 1421763..1422008 | - | 246 | WP_209186794.1 | hypothetical protein | - |
| J5278_RS24560 (J5278_24580) | 1422185..1422415 | + | 231 | WP_209186795.1 | helix-turn-helix transcriptional regulator | Antitoxin |
| J5278_RS24565 (J5278_24585) | 1422412..1423674 | + | 1263 | WP_209186796.1 | type II toxin-antitoxin system HipA family toxin | Toxin |
| J5278_RS31235 | 1424410..1424466 | + | 57 | WP_257623477.1 | hypothetical protein | - |
| J5278_RS24575 (J5278_24595) | 1424958..1425767 | - | 810 | WP_209186797.1 | mechanosensitive ion channel | - |
| J5278_RS24580 (J5278_24600) | 1425998..1426768 | - | 771 | WP_209186798.1 | SDR family NAD(P)-dependent oxidoreductase | - |
| J5278_RS24585 (J5278_24605) | 1427373..1427801 | + | 429 | WP_209187847.1 | MucR family transcriptional regulator | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 421 a.a. Molecular weight: 45307.99 Da Isoelectric Point: 5.7044
>T197443 WP_209186796.1 NZ_CP072163:1422412-1423674 [Rhizobium sp. B21/90]
MTVRVLNVWWNGRIVGQFTQDQHGDIGFAYAEAWLEDEKALPLSVSLPKRPERFSRRECRPFFGGLLPEESQRLVAAQAL
GVSPANDFALLDRLGGDVAGALQLLPEDQEPIGGGLIADRQTAALDEVGIVRILDALPTRPLLAGQEGLRLSLAGAQSKA
PVVLIDGQVALPLPGQATTHILKPPIARFPGTTENEAFAMRLAAAIGLDVAPVDPRSANGRPFLLVNRYDRHHDGDGVVL
RIHQEDFCQALGVPPETKYASEGGPTFKDCFELLRRVSARPGTDIAKLLDAAIFNLVIGNADAHGKNFSILYDHSGPRMA
PLYDLLSTVAYPDLSPKLAMRIGKRATLADMDADGWQAFSKETGVSLPLVRRRVKELTDATGDAIPRLLEDMSPLAADPV
SLNRVAALIADRAKLVALSI
MTVRVLNVWWNGRIVGQFTQDQHGDIGFAYAEAWLEDEKALPLSVSLPKRPERFSRRECRPFFGGLLPEESQRLVAAQAL
GVSPANDFALLDRLGGDVAGALQLLPEDQEPIGGGLIADRQTAALDEVGIVRILDALPTRPLLAGQEGLRLSLAGAQSKA
PVVLIDGQVALPLPGQATTHILKPPIARFPGTTENEAFAMRLAAAIGLDVAPVDPRSANGRPFLLVNRYDRHHDGDGVVL
RIHQEDFCQALGVPPETKYASEGGPTFKDCFELLRRVSARPGTDIAKLLDAAIFNLVIGNADAHGKNFSILYDHSGPRMA
PLYDLLSTVAYPDLSPKLAMRIGKRATLADMDADGWQAFSKETGVSLPLVRRRVKELTDATGDAIPRLLEDMSPLAADPV
SLNRVAALIADRAKLVALSI
Download Length: 1263 bp
>T197443 NZ_CP096170:c14266-13916 [Shewanella sp. JNE2]
ATGTGGGTCATCGAGACAACCGACACCTTTGATGAGTGGTTCGATGCTCTGGATGATACCGATAGAGCAAACGTGCTGGC
TTCGATGATGGTGCTGCGAGATAGAGGCCCCATGCTGTCGAGGCCATACGCGGATACTGTTAACGGTTCATCCTACAGCA
ACATGAAAGAGCTTCGGGTCCAAAGCAAAGGAGATCCTATCAGAGCGTTCTTTGCGTTCGATCCAAAGCGTAAGGGGATT
CTTCTCTGCGCCGGTAACAAGACCGGGGACGAGAAAAGGTTTTATGAAGTAATGATCCCAATTGCAGACCGTGAGTTTGC
GGCGCACTTGGATAAATTGAAGAAGGAGTGA
ATGTGGGTCATCGAGACAACCGACACCTTTGATGAGTGGTTCGATGCTCTGGATGATACCGATAGAGCAAACGTGCTGGC
TTCGATGATGGTGCTGCGAGATAGAGGCCCCATGCTGTCGAGGCCATACGCGGATACTGTTAACGGTTCATCCTACAGCA
ACATGAAAGAGCTTCGGGTCCAAAGCAAAGGAGATCCTATCAGAGCGTTCTTTGCGTTCGATCCAAAGCGTAAGGGGATT
CTTCTCTGCGCCGGTAACAAGACCGGGGACGAGAAAAGGTTTTATGAAGTAATGATCCCAATTGCAGACCGTGAGTTTGC
GGCGCACTTGGATAAATTGAAGAAGGAGTGA
Antitoxin
Download Length: 77 a.a. Molecular weight: 8069.42 Da Isoelectric Point: 10.5998
>AT197443 WP_209186795.1 NZ_CP072163:1422185-1422415 [Rhizobium sp. B21/90]
MAKQVSSPAEIGALIRSTRKAQNLRQDELAGVSGVGLRFIVDLEAGKPTAQIGKVLQVLQTLGCSIDILAPGERRK
MAKQVSSPAEIGALIRSTRKAQNLRQDELAGVSGVGLRFIVDLEAGKPTAQIGKVLQVLQTLGCSIDILAPGERRK
Download Length: 231 bp
>AT197443 NZ_CP096170:c13911-13609 [Shewanella sp. JNE2]
ATGGCAAGAACTCTTGACCAAATGCTGGCAACAGAAAAGCCTGAGGTTGTTGCCAAAGCACAGAAAGCGGCCACTGAGAT
GTTACTGAACATCCACTTGGCAGAGCTTCGTGATCGCATGAACCTTACCCAGGGGGAAATTGCTGCATCTCTGGGTGTGA
GACAGCCGACAGTCTCCGAGATGGAAAAACCTGGACGAGATCTCAAGCTGTCGTCCATTAAGCGGTACGTTGAGGCCTCC
GGTGGCAAGCTACGCCTCGATGTTGAACTTCCGGACGGCACCCACTACGGCTTTGCCGTTTAA
ATGGCAAGAACTCTTGACCAAATGCTGGCAACAGAAAAGCCTGAGGTTGTTGCCAAAGCACAGAAAGCGGCCACTGAGAT
GTTACTGAACATCCACTTGGCAGAGCTTCGTGATCGCATGAACCTTACCCAGGGGGAAATTGCTGCATCTCTGGGTGTGA
GACAGCCGACAGTCTCCGAGATGGAAAAACCTGGACGAGATCTCAAGCTGTCGTCCATTAAGCGGTACGTTGAGGCCTCC
GGTGGCAAGCTACGCCTCGATGTTGAACTTCCGGACGGCACCCACTACGGCTTTGCCGTTTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|