Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/PRK09812-ChpS
Location 3425290..3425876 Replicon chromosome
Accession NZ_CP072162
Organism Rhizobium sp. B21/90

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag J5278_RS16590 Protein ID WP_209182789.1
Coordinates 3425290..3425619 (-) Length 110 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag J5278_RS16595 Protein ID WP_209182788.1
Coordinates 3425619..3425876 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J5278_RS16575 (J5278_16580) 3420975..3421316 + 342 WP_209182792.1 hypothetical protein -
J5278_RS16580 (J5278_16585) 3421728..3423941 - 2214 WP_209182791.1 FAD-dependent oxidoreductase -
J5278_RS16585 (J5278_16590) 3424034..3425242 - 1209 WP_209182790.1 acetyl-CoA C-acetyltransferase -
J5278_RS16590 (J5278_16595) 3425290..3425619 - 330 WP_209182789.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
J5278_RS16595 (J5278_16600) 3425619..3425876 - 258 WP_209182788.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
J5278_RS16600 (J5278_16605) 3425963..3427759 - 1797 WP_209187324.1 acyl-CoA dehydrogenase C-terminal domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-109)

Antitoxin

Antitoxin PemI-like

(4-84)


Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 11877.67 Da        Isoelectric Point: 9.8009

>T197440 WP_209182789.1 NZ_CP072162:c3425619-3425290 [Rhizobium sp. B21/90]
VDRGDIWHVDLEPIRGREQAGARYVLVVTKKSFNAIGTPIVVPITTGGEFARFKGFAVSLSGAGTRSSGVIMCNQLRSLD
LRARGGKYVESVPDFIMSEVLARISTFFD

Download         Length: 330 bp

>T197440 NZ_CP096169:c3382916-3381978 [Shewanella sp. JNE2]
ATGGATAAAGATAGCCCATATTACAAACAGGTTTCCTTGCTCATAAGAATGCTTCCTGTGGTAGCAACAGAGACGGTTTT
TGCACTTAAAGGTGGCACCGCCATTAATTTATTTGTGAGAGATTTTCCTCGGTTATCTGTAGATATTGATCTTGCTTATC
TTCCACTTGAACCAAGAGATGAGGCTTTGATTAATGTCAGGGCTGCATTGCAGCGCATTACAGACAGAATCAATACTCAA
CCAGATATCAGAGCGGCATTTCAGGATAATAAAGCTGATGAACTGAGAATAGTTGTATCAAGTCCGGTTGCGACGATCAA
AATTGAAGTGTCGCCCGTCGCCAGAGGTACATTGCATAGTGCAGAAATAATGCCAGTTCAAGAGTCTGTTGAAGACGAGT
TTGGTTATGCTGAGATTCAGGTAGTCAGTCTTCCCGATCTGTATGGTGGGAAATTGTGTGCTGCAATGGATCGCCAACAT
CCTCGCGACTTATTTGATGTGCGTATGTTACTTGGCAGTGAAGGGATTTCGAGAGAGATTTTGGTGGGTTTTTTAACCTA
TACATTAAGTCACCCTCGGCCTATTAATGAAGTCATGTCGCCAAACTGGCAGCCTCTGAATGAGAAATTTCAGGCAGAAT
TTGACGGAATGACTTTTGAAAAAGTTGAATGCGAAGACTTAGCCTCTGTTAGGCCCATGATGTTAATTGAACTGCAAAAA
CATTTCACAGAAAGGGATCATGCTTTCCTTATGTCATTCAAAAGAGGGCAACCTGACTGGGCATTGTTTGACTATCCTAA
TGCAGCAGACTTGCCAGCGATTCGTTGGAAATTGCAGAACATTAACAAATTGGCAAAGAATCAAGCAAAACACCAAGAGC
AATTAGATAAATTGAAGCAAGTGCTTGATGATTGGCTTGTTAACGCAAACGCCGAGTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9295.58 Da        Isoelectric Point: 4.3184

>AT197440 WP_209182788.1 NZ_CP072162:c3425876-3425619 [Rhizobium sp. B21/90]
MATSTLRNVGGSVMMTIPKAVVDELGLTANTKVEVLAEDGRVVAVPHKRPKYTLDELLAQCDLDAPFTEEDRQWLDDAPS
GREVI

Download         Length: 258 bp

>AT197440 NZ_CP096169:c3383700-3382909 [Shewanella sp. JNE2]
ATGTCATCTAAAATAAACTGGCTTGTTGCTCATACTTCTCCTGGTGCGCTAGTACTTCAGCAATGGCTGACTGAAAACGG
CGTGAGCTACTCGTTGGCTCAAAAGTACGCGCAGAACGGTTGGCTAAAGAAGCTTAGTTCTGGTGTGTACTATCGTCCAA
ATGCGCAGGGCGATATAAAGCCAACTTGGGTTGATGCCATTCAAGCATTGGATGTGCAATTGGGCGTTTCAGTTCATTTG
GCTGGATTGAGCAGCTTAACTCACCAAGGACTGAGTCACTATTTGCAGCTGAACAAAGAGCAAGTTTGGATTTGCGTTAA
AAACAAGTCGTCCTTACCGAAATGGTTTCGTGAATTCCCTTATCAGAATTGGTTTTACTGCGGAAACCATAAGCTTGAAG
TGAATCCCGAGAAGGATTTGAAAAGGATCACGGTTAAAGAGAAAGAGCTCACTGTCAGCTGTGCAGAACTTGCTGCCTAT
GAAGTGGTAGACGCGATTGGGAAGCTGATTTCATTTGAGCATGTCGCAGAATTATTTCAGGGTTTAGTCAATCTTAGCCC
TAGAAAAGTACAAGATATTCTTGAACGAAGCAGCTCTGTTCAGGCAAACCGAATATTTCTATTTCTGGGTCGATACTACG
ATCACCAGTGGGTCAATCGCATAGATGAAACAAGAATTGAATTGGGTGCAGGAAAGCGACAGGTTGTCGAAAAAGGACGT
TTTGATGAGCGATATCAAATCACAGTGCCAGAGATATTAAGCGTCAAAAAAGGTGAACAACATAATGGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References