197437

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 3082989..3083469 Replicon chromosome
Accession NZ_CP072162
Organism Rhizobium sp. B21/90

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag J5278_RS14930 Protein ID WP_209183044.1
Coordinates 3082989..3083261 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag J5278_RS14935 Protein ID WP_209187348.1
Coordinates 3083245..3083469 (-) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J5278_RS14920 (J5278_14920) 3078203..3081661 - 3459 WP_209183046.1 chromosome segregation SMC family protein -
J5278_RS14925 (J5278_14925) 3082082..3082777 - 696 WP_209183045.1 DsbA family protein -
J5278_RS14930 (J5278_14930) 3082989..3083261 - 273 WP_209183044.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
J5278_RS14935 (J5278_14935) 3083245..3083469 - 225 WP_209187348.1 DUF6290 family protein Antitoxin
J5278_RS14940 (J5278_14940) 3083532..3084032 - 501 WP_209183042.1 DUF721 domain-containing protein -
J5278_RS14945 (J5278_14945) 3084132..3085211 + 1080 WP_209183059.1 A/G-specific adenine glycosylase -
J5278_RS14950 (J5278_14950) 3085228..3085842 + 615 WP_209183041.1 HAD family phosphatase -
J5278_RS14955 (J5278_14955) 3085847..3086212 + 366 WP_111217840.1 nuclear transport factor 2 family protein -
J5278_RS14960 (J5278_14960) 3086327..3087460 - 1134 WP_209183040.1 site-specific DNA-methyltransferase -
J5278_RS14965 (J5278_14965) 3087605..3087901 + 297 WP_142824229.1 nucleotidyltransferase domain-containing protein -
J5278_RS14970 (J5278_14970) 3087902..3088249 + 348 WP_209183039.1 DUF86 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-88)

Antitoxin

Relaxosome protein TraY

(4-49)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10710.28 Da        Isoelectric Point: 10.3301

>T197437 WP_209183044.1 NZ_CP072162:c3083261-3082989 [Rhizobium sp. B21/90]
MAWRIEFQRPAERDLEKLDHESVKRILRFLHTRVASLEDPRSIGEALRGSELGNFWKYRVGDYRIIADIDDGTVRILVVR
IGNRKDVYRR

Download         Length: 273 bp

>T197437 NZ_CP096169:2904317-2904571 [Shewanella sp. JNE2]
ATGAACAAAAAACATTTAAGAACGTTGACGGCTATCTTTGCTAGGCCTGTCAGCGGAGCTATCAAGTGGTCTGATATTGA
AGCGCTGTTTATTGCTCTAGGGGCTGACATTGAAGAGCGTGAGGGGTCTCGAATTGGTGTGGTGCTGTTTGGTGAAGTTC
AGGTATATCACCGCCCACATCCTCAGAAAGAAACTGACAAAGACGCAGTGATAAACATCAAAAAATGGTTAGAAAGGAAC
GGGGTGAAAGCATGA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8542.61 Da        Isoelectric Point: 4.5355

>AT197437 WP_209187348.1 NZ_CP072162:c3083469-3083245 [Rhizobium sp. B21/90]
MLALRLPPDIEARLDELAKRTGRSKSFYARQAILEHLDDLEDLYVAEQRLEEFRRGDSDSISLAELMARHGVED

Download         Length: 225 bp

>AT197437 NZ_CP096169:2904568-2904909 [Shewanella sp. JNE2]
ATGAAAAATCTTATGATGATCAACGGGGTAAAAGCCTTTATTGATTATGATCCAGACGCTGAAACATTCCGTGGTGAGTT
CGTAGGCTTAAACGGCGGCGCGGATTTCTATGGTGAAAGCGTCGCTCAATTGGAAGCCGAGGGCGCGAAGTCATTAAGCG
TTTTTTTAGAGATGTGTCAGGAGCGTGGCATTGAGCCTTACAAAAACTTCTCTGGCAAATTCAACGTTCGGATCTCGCCA
GAGGTTCACGCTCGACTTAATGAAATTGCGCTATCGCAAAGCATTAGTTTGAATGCAGCGGTAGAAAATGCAGTCAATGA
CTACATTGCACATTCAGCGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References