Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/HTH_26(antitoxin)
Location 2997669..2998283 Replicon chromosome
Accession NZ_CP072162
Organism Rhizobium sp. B21/90

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag J5278_RS14495 Protein ID WP_209183151.1
Coordinates 2998038..2998283 (-) Length 82 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag J5278_RS14490 Protein ID WP_209187356.1
Coordinates 2997669..2998031 (-) Length 121 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J5278_RS14465 (J5278_14470) 2992893..2993147 - 255 WP_209183157.1 type II toxin-antitoxin system ParD family antitoxin -
J5278_RS14470 (J5278_14475) 2993349..2993897 - 549 WP_209183156.1 HdeD family acid-resistance protein -
J5278_RS14475 (J5278_14480) 2994067..2994666 + 600 WP_209183155.1 transcriptional regulator BetI -
J5278_RS14480 (J5278_14485) 2994663..2996192 + 1530 WP_209183154.1 choline-sulfatase -
J5278_RS14485 (J5278_14490) 2996194..2997657 + 1464 WP_209183153.1 betaine-aldehyde dehydrogenase -
J5278_RS14490 (J5278_14495) 2997669..2998031 - 363 WP_209187356.1 helix-turn-helix transcriptional regulator Antitoxin
J5278_RS14495 (J5278_14500) 2998038..2998283 - 246 WP_209183151.1 cytotoxic translational repressor of toxin-antitoxin stability system Toxin
J5278_RS14500 (J5278_14505) 2998377..3000029 + 1653 WP_209183150.1 choline dehydrogenase -
J5278_RS14505 (J5278_14510) 3000057..3001115 - 1059 WP_209183149.1 LacI family DNA-binding transcriptional regulator -
J5278_RS14510 (J5278_14515) 3001670..3001969 - 300 WP_209183148.1 type II toxin-antitoxin system RelE/ParE family toxin -
J5278_RS14515 (J5278_14520) 3001966..3002241 - 276 WP_209183147.1 YlcI/YnfO family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(67-114)


Sequences

Toxin        


Download         Length: 82 a.a.        Molecular weight: 9209.05 Da        Isoelectric Point: 10.9851

>T197436 WP_209183151.1 NZ_CP072162:c2998283-2998038 [Rhizobium sp. B21/90]
MKDVVVSRLADKALMRMQPKRRLAIIEKVKAYARGEIVDIKKMKGGNLYRIRVGQDRVIIDDKGRIVVVIDAGPRGSIYK
E

Download         Length: 246 bp

>T197436 NZ_CP096169:2019285-2019674 [Shewanella sp. JNE2]
ATGGATATCATCTGTTTTCCTTTTGAACGTGTGGTCGAAATTAATGCGTTAATCCTTTCGACAGAGCCCGGCATGAAAGG
TGCGGTTGATATTCCTAAACTTCAGGGAGCGTTGAGCCGTATTGACAATGCGATTGTCTACCAAGGCTTAGATGATGTGT
TTGAGATTGCTGCAAAATACACTGCTTGTATAGCGGTATCTCACGCTTGTCCTGATGCAAATAAGCGAACTGGTTTAGCA
GTAGCACTCGAATACTTATCTCTAAACGACTATGAAATCACAGAGGATAATGAACTGCTAGCGAATGCTATCCGAGACTT
AGTGCTTCAAGAGATTACCGAGACTGACTTTGCTGACATTCTTTATGCTCAGTATCTCAAGGGGTTGTAA

Antitoxin


Download         Length: 121 a.a.        Molecular weight: 13066.79 Da        Isoelectric Point: 4.3246

>AT197436 WP_209187356.1 NZ_CP072162:c2998031-2997669 [Rhizobium sp. B21/90]
MGDIKRFEIDGKPYVLLSEEDYEDLVDGLRANAVLAGISAGEETWPLEIVEARANGGNAVRIFRNYRRMTVTELATAAGI
SQPYLSEIEAGKKTGSVDVLKRIANALKVDLDDLVVNVAD

Download         Length: 363 bp

>AT197436 NZ_CP096169:2019115-2019285 [Shewanella sp. JNE2]
ATGAATCGAAAATTAGAAGTTTACGGTGTTCAAGTGGTAACTAGACCGAAGATCAAGGCGACCAAACAACTTGATTTATC
AGGTGACTTTGGACGTCAAATCGTTAAGTCAGAAACCAAACTAGCATTAAGAACCCATCCCAAAACTTTCCAAAAGTTGG
CTGATATGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References