197432

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 1481047..1481711 Replicon chromosome
Accession NZ_CP072157
Organism Rhizobium sp. B230/85

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag J5289_RS24830 Protein ID WP_209186127.1
Coordinates 1481283..1481711 (+) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag J5289_RS24825 Protein ID WP_142831607.1
Coordinates 1481047..1481286 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J5289_RS24805 (J5289_24800) 1477631..1478035 + 405 WP_209207008.1 helix-turn-helix transcriptional regulator -
J5289_RS24810 (J5289_24805) 1479095..1479439 - 345 WP_209207006.1 hypothetical protein -
J5289_RS24815 (J5289_24810) 1479789..1480037 + 249 WP_142831608.1 hypothetical protein -
J5289_RS24820 (J5289_24815) 1480077..1480791 + 715 Protein_1351 IS6 family transposase -
J5289_RS24825 (J5289_24820) 1481047..1481286 + 240 WP_142831607.1 Arc family DNA-binding protein Antitoxin
J5289_RS24830 (J5289_24825) 1481283..1481711 + 429 WP_209186127.1 type II toxin-antitoxin system VapC family toxin Toxin
J5289_RS24835 (J5289_24830) 1481783..1482073 + 291 WP_209207003.1 hypothetical protein -
J5289_RS24840 (J5289_24835) 1482342..1483037 - 696 WP_209207002.1 alpha/beta fold hydrolase -
J5289_RS24845 (J5289_24840) 1483377..1484051 - 675 WP_244615504.1 permease -
J5289_RS24850 (J5289_24845) 1484431..1484859 - 429 WP_209207001.1 hypothetical protein -
J5289_RS24855 (J5289_24850) 1485082..1485909 - 828 WP_209186131.1 aldo/keto reductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin

Arc-like DNA binding domain

(9-46)


Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15224.51 Da        Isoelectric Point: 5.8927

>T197432 WP_209186127.1 NZ_CP072157:1481283-1481711 [Rhizobium sp. B230/85]
MILLDTNVISEPLKSQPDPRVAAWIDTQAVETLYVAAISLAELRYGIAVHPDGKKKQAVQEKLDRLMLPLFRGRIMPFDE
AAAQAYAELRAAAAKKGKAIGDSDGYIAATAKANGLMIATRDTSPFEAAGLTVINPWEASNG

Download         Length: 429 bp

>T197432 NZ_CP096167:c115340-114990 [Shewanella sp. JNE7]
ATGTGGGTCATCGAGACAACCGACACCTTTGATGAGTGGTTCGATGCTCTGGATGATACCGATAGAGCAAACGTGCTGGC
TTCGATGATGGTGCTGCGAGATAGAGGCCCCATGCTGTCGAGGCCATACGCGGATACTGTTAACGGTTCATCCTACAGCA
ACATGAAAGAGCTTCGGGTCCAAAGCAAAGGAGATCCTATCAGAGCGTTCTTTGCGTTCGATCCAAAGCGTAAGGGGATT
CTTCTCTGCGCCGGTAACAAGACCGGGGACGAGAAAAGGTTTTATGAAGTAATGATCCCAATTGCAGACCGTGAGTTTGC
GGCGCACTTGGATAAATTGAAGAAGGAGTGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8652.88 Da        Isoelectric Point: 7.2054

>AT197432 WP_142831607.1 NZ_CP072157:1481047-1481286 [Rhizobium sp. B230/85]
MASITIRNVPDEVHRALRVRAAQHGRSAEAEIRIILEQAAKPEGRVKLGSLLTQIGQEVGGLDLTIERDRTPSPPVSFE

Download         Length: 240 bp

>AT197432 NZ_CP096167:c114985-114683 [Shewanella sp. JNE7]
ATGGCAAGAACTCTTGACCAAATGCTGGCAACAGAAAAGCCTGAGGTTGTTGCCAAAGCACAGAAAGCGGCCACTGAGAT
GTTACTGAACATCCACTTGGCAGAGCTTCGTGATCGCATGAACCTTACCCAGGGGGAAATTGCTGCATCTCTGGGTGTGA
GACAGCCGACAGTCTCCGAGATGGAAAAACCTGGACGAGATCTCAAGCTGTCGTCCATTAAGCGGTACGTTGAGGCCTCC
GGTGGCAAGCTACGCCTCGATGTTGAACTTCCGGACGGCACCCACTACGGCTTTGCCGTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References