Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 669968..670653 Replicon chromosome
Accession NZ_CP072157
Organism Rhizobium sp. B230/85

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag J5289_RS21150 Protein ID WP_209207976.1
Coordinates 670231..670653 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag J5289_RS21145 Protein ID WP_209207977.1
Coordinates 669968..670234 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J5289_RS21120 (J5289_21120) 665404..666864 - 1461 WP_209207982.1 UbiA family prenyltransferase -
J5289_RS29415 667142..667935 + 794 Protein_606 transposase -
J5289_RS21135 (J5289_21135) 668049..668483 + 435 WP_209207979.1 hypothetical protein -
J5289_RS21140 (J5289_21140) 668491..669408 + 918 WP_209207978.1 HEPN domain-containing protein -
J5289_RS21145 (J5289_21145) 669968..670234 + 267 WP_209207977.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
J5289_RS21150 (J5289_21150) 670231..670653 + 423 WP_209207976.1 type II toxin-antitoxin system VapC family toxin Toxin
J5289_RS21155 (J5289_21155) 670690..671334 + 645 WP_209207975.1 hypothetical protein -
J5289_RS21160 (J5289_21160) 671717..672138 - 422 Protein_612 MucR family transcriptional regulator -
J5289_RS21165 (J5289_21165) 672680..673003 + 324 WP_209207974.1 hypothetical protein -
J5289_RS29420 673148..673273 - 126 WP_257625516.1 hypothetical protein -
J5289_RS21170 (J5289_21170) 673498..674397 + 900 WP_209207973.1 HEPN domain-containing protein -
J5289_RS21175 (J5289_21175) 674872..675576 + 705 WP_247750846.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-125)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(10-71)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15605.05 Da        Isoelectric Point: 5.7698

>T197431 WP_209207976.1 NZ_CP072157:670231-670653 [Rhizobium sp. B230/85]
MRLLLDTNVLSEVTKLRPAERVLNWLHGLDEDRTFISIISIAEIRRGVALMDIGRKRDALDAWLTDDLPRRFENRIIPVE
AHVALAWGDLMALAKRSGRGLASMDGLIAATAVARDLTLATRNTKDFDGFGIDLVDPWAV

Download         Length: 423 bp

>T197431 NZ_CP096166:c4481309-4481103 [Shewanella sp. JNE7]
GTGAGTTATTCCAAAATTTTCAAAGAATTGGATAAATCACTACACGATAGAGCATCATTTGACTGTGGCGAAGCAGAGTT
AAACGATTTTATCCAAACTCAAGCAGCAAAACATATGCAAGCAGGTATTAGCCGTACAATGGCGGCGTTTTTCAAGCTAG
TTGTCACCATCGACCGTTTTAAGCGGCCTTTTTTTCCACTTCTTTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9775.03 Da        Isoelectric Point: 7.0166

>AT197431 WP_209207977.1 NZ_CP072157:669968-670234 [Rhizobium sp. B230/85]
MRASTHDDMSWTVAGAKARLSEVMERAQSAPQTITRNGKPSVVVVSAEEWEKKTARRGSLAEFLLASPLRGADLDNERLR
DEPRDLPL

Download         Length: 267 bp

>AT197431 NZ_CP096166:c4481575-4481306 [Shewanella sp. JNE7]
ATGGCGACTGCAAGACTTGATATCCGTTTGGATGAAGAAATCAAAGCTAAGGCTGAGAAAGCATCCGCTTTGCTCGGGTT
AAAAAGCTTAACTGAATACGTTGTTCGCTTAATGGACGAAGATGCAACTCAGGTGATAGCTGAGCATGAAAGCGTTACGG
TTAAAGCAGATGTATTCGACCAATTCATAATGGCTTGTGATGAGGCTAAGGTTCCGAATAAGGCATTGCGTGAAGCGGCT
GCATTTACTAAAAATGGTGAGTTTAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References