Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 353678..354258 Replicon chromosome
Accession NZ_CP072157
Organism Rhizobium sp. B230/85

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag J5289_RS29355 Protein ID WP_257625532.1
Coordinates 353678..354034 (-) Length 119 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag J5289_RS19790 Protein ID WP_142831764.1
Coordinates 354058..354258 (-) Length 67 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J5289_RS19775 (J5289_19780) 350590..351063 - 474 Protein_332 FCD domain-containing protein -
J5289_RS19780 (J5289_19785) 351608..352351 - 744 WP_209185940.1 hypothetical protein -
J5289_RS19785 (J5289_19790) 352335..353408 - 1074 WP_209185941.1 AAA family ATPase -
J5289_RS29355 353678..354034 - 357 WP_257625532.1 type II toxin-antitoxin system VapC family toxin Toxin
J5289_RS19790 (J5289_19795) 354058..354258 - 201 WP_142831764.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
J5289_RS19795 (J5289_19800) 354389..355393 - 1005 WP_209185988.1 C-terminal binding protein -
J5289_RS19800 (J5289_19805) 355398..356369 - 972 WP_209208008.1 2-dehydropantoate 2-reductase N-terminal domain-containing protein -
J5289_RS19805 (J5289_19810) 356382..357563 - 1182 WP_209185944.1 acyl-CoA dehydrogenase family protein -
J5289_RS19810 (J5289_19815) 357683..358786 - 1104 WP_209185945.1 LLM class flavin-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-42)


Sequences

Toxin        


Download         Length: 119 a.a.        Molecular weight: 12967.00 Da        Isoelectric Point: 9.6881

>T197430 WP_257625532.1 NZ_CP072157:c354034-353678 [Rhizobium sp. B230/85]
IDHFRHGDVELRKVIADDRLLCHPVVVGELALGSLRDRGAVMAFFSAQREALVASHYEVITMIGRHSIFSMGIGYTDAHL
LASILLDRRSLLWTRDKRLAAAARKAGASLYAPTSAPN

Download         Length: 357 bp

>T197430 NZ_CP096166:c3431995-3431057 [Shewanella sp. JNE7]
ATGGATAAAGATAGCCCATATTACAAACAGGTTTCCTTGCTCATAAGAATGCTTCCTGTGGTAGCAACAGAGACGGTTTT
TGCACTTAAAGGTGGCACCGCCATTAATTTATTTGTGAGAGATTTTCCTCGGTTATCTGTAGATATTGATCTTGCTTATC
TTCCACTTGAACCAAGAGATGAGGCTTTGATTAATGTCAGGGCTGCATTGCAGCGCATTACAGACAGAATCAATACTCAA
CCAGATATCAGAGCGGCATTTCAGGATAATAAAGCTGATGAACTGAGAATAGTTGTATCAAGTCCGGTTGCGACGATCAA
AATTGAAGTGTCGCCCGTCGCCAGAGGTACATTGCATAGTGCAGAAATAATGCCAGTTCAAGAGTCTGTTGAAGACGAGT
TTGGTTATGCTGAGATTCAGGTAGTCAGTCTTCCCGATCTGTATGGTGGGAAATTGTGTGCTGCAATGGATCGCCAACAT
CCTCGCGACTTATTTGATGTGCGTATGTTACTTGGCAGTGAAGGGATTTCGAGAGAGATTTTGGTGGGTTTTTTAACCTA
TACATTAAGTCACCCTCGGCCTATTAATGAAGTCATGTCGCCAAACTGGCAGCCTCTGAATGAGAAATTTCAGGCAGAAT
TTGACGGAATGACTTTTGAAAAAGTTGAATGCGAAGACTTAGCCTCTGTTAGGCCCATGATGTTAATTGAGCTGCAAAAA
CATTTCACAGAAAGGGATCATGCTTTCCTTATGTCATTCAAAAGAGGGCAACCTGACTGGGCATTGTTTGACTATCCTAA
TGCAGCAGACTTGCCAGCGATTCGTTGGAAATTGCAGAACATTAACAAATTGGCAAAGAATCAAGCAAAACACCAAGAGC
AATTAGATAAATTGAAGCAAGTGCTTGATGATTGGCTTGTTAACGCAAACGCCGAGTAA

Antitoxin


Download         Length: 67 a.a.        Molecular weight: 7125.13 Da        Isoelectric Point: 10.4525

>AT197430 WP_142831764.1 NZ_CP072157:c354258-354058 [Rhizobium sp. B230/85]
MRSTINLDDNLMEQARSLTGTKETAALVRQALETLVRVESGKRLAALGGTMPDAEAAPRRRSEAAK

Download         Length: 201 bp

>AT197430 NZ_CP096166:c3432779-3431988 [Shewanella sp. JNE7]
ATGTCATCTAAGATAAACTGGCTTGTTGCTCATACTTCTCCTGGTGCGCTAGTACTTCAGCAATGGCTGACTGAAAACGG
TGTGAGCTACTCCCTGGCTCAAAAGTACGCGCAGAACGGTTGGCTGAAGAAGCTTAGTTCTGGCGTGTACTATCGTCCAG
ATGCGCAGGGCGATATAAAGCCAACTTGGGTTGATGCCATTCAAGCATTAGATGTGCAATTGGGCGTTTCAGTTCATTTG
GCTGGATTGAGCAGCTTAACTCACCAAGGACTGAGTCACTATTTACAGCTGAACAAAGAGCAAGTTTGGATTTGCGTTAA
AAATAAGTCGTCCTTACCAAAATGGTTTCGTGAATTCCCTTATCAGAATTGGTTTTACTGTGGAAACCATAAGCTTGAAG
TGAATCCCGAGAAAGATTTGAAAAGGATCACGGTTAAAGAGAAAGAACTCACTGTCAGCTGTGCAGAACTTGCTGCCTAT
GAAGTGGTAGACGCGATTGGGAAGCTGATTTCATTTGAGCATGTCGCAGAATTATTTCAGGGTTTAGTCAATCTTAGCCC
TAGAAAAGTACAAGATATTCTTGAGCGAAGCAGCTCTGTTCAGGCAAACCGAATATTTCTATTTCTGGGTCGATACTACG
ATCACCAGTGGGTCAATCGCATAGATGAAACAAGAATTAAATTGGGGGCAGGAAAGCGGCAGGTTGTCGAAAAAGGACGT
TTTGATGAGCGATATCAAATCACAGTGCCAGAGATATTAAGCGTCAAAAAAGGTGAACAACATAATGGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References