Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | rlegTA/AbiEii-AbiEi |
| Location | 125481..126972 | Replicon | chromosome |
| Accession | NZ_CP072157 | ||
| Organism | Rhizobium sp. B230/85 | ||
Toxin (Protein)
| Gene name | rlegT | Uniprot ID | - |
| Locus tag | J5289_RS18825 | Protein ID | WP_209208065.1 |
| Coordinates | 126094..126972 (+) | Length | 293 a.a. |
Antitoxin (Protein)
| Gene name | rlegA | Uniprot ID | - |
| Locus tag | J5289_RS18820 | Protein ID | WP_209186736.1 |
| Coordinates | 125481..126101 (+) | Length | 207 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| J5289_RS18800 (J5289_18805) | 120683..121756 | - | 1074 | WP_209185873.1 | inositol-3-phosphate synthase | - |
| J5289_RS18805 (J5289_18810) | 121741..122787 | - | 1047 | WP_209185874.1 | Gfo/Idh/MocA family oxidoreductase | - |
| J5289_RS18810 (J5289_18815) | 122903..123835 | + | 933 | WP_209185875.1 | LysR substrate-binding domain-containing protein | - |
| J5289_RS18815 (J5289_18820) | 123836..124717 | + | 882 | WP_209185876.1 | NAD(P)-dependent oxidoreductase | - |
| J5289_RS18820 (J5289_18825) | 125481..126101 | + | 621 | WP_209186736.1 | AbiEi antitoxin N-terminal domain-containing protein | Antitoxin |
| J5289_RS18825 (J5289_18830) | 126094..126972 | + | 879 | WP_209208065.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
| J5289_RS29310 | 126982..127104 | + | 123 | WP_257625492.1 | hypothetical protein | - |
| J5289_RS18830 (J5289_18835) | 127466..127714 | + | 249 | Protein_139 | DUF1330 domain-containing protein | - |
| J5289_RS18840 (J5289_18845) | 129024..129287 | + | 264 | WP_257623454.1 | inositol monophosphatase family protein | - |
| J5289_RS18845 (J5289_18850) | 129581..130165 | + | 585 | WP_209186535.1 | sigma-70 family RNA polymerase sigma factor | - |
| J5289_RS18850 (J5289_18855) | 130162..130803 | + | 642 | WP_247749522.1 | NrsF family protein | - |
| J5289_RS18855 (J5289_18860) | 131444..131791 | + | 348 | WP_209187428.1 | transposase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Integrative and Conjugative Element | - | - | 816..210099 | 209283 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 293 a.a. Molecular weight: 32746.54 Da Isoelectric Point: 5.1270
>T197429 WP_209208065.1 NZ_CP072157:126094-126972 [Rhizobium sp. B230/85]
MAKTPANMAKSVKDRLLNIARKESRAFDVLLVRFALERLLYRLSISAHRDRFVLKGGMLVTVWVADDNRVTRDADFLGHG
DADPARLIADFGEIMAIESDDGLAFDIDALAATTIREEMEYGGVRLRTAAYLERTRISVTIDIGFGDAMADATQRLDYPA
LLDFPAPQVRSYPPATVIAEKFQAMVALGVLNGRMKDYYDLWAIPRAIDIPADDLDAAIRVTFERRRTPIPRERPPGLSV
EMFSDEGKQRQWRAYAASLELEAVSLESIIERVWELIGPSCARIVARNDNKT
MAKTPANMAKSVKDRLLNIARKESRAFDVLLVRFALERLLYRLSISAHRDRFVLKGGMLVTVWVADDNRVTRDADFLGHG
DADPARLIADFGEIMAIESDDGLAFDIDALAATTIREEMEYGGVRLRTAAYLERTRISVTIDIGFGDAMADATQRLDYPA
LLDFPAPQVRSYPPATVIAEKFQAMVALGVLNGRMKDYYDLWAIPRAIDIPADDLDAAIRVTFERRRTPIPRERPPGLSV
EMFSDEGKQRQWRAYAASLELEAVSLESIIERVWELIGPSCARIVARNDNKT
Download Length: 879 bp
>T197429 NZ_CP096166:3061763-3062179 [Shewanella sp. JNE7]
TTGAATGACATTATTATCAACAAAATAGCAACCATCAAACGCTGTATAAAACGCATCCAACAAGTTTATGGTGATGGCAG
CATGTTCAAACAAGACTTCACCCTGCAAGATAGCGTTATCCTCAATTTACAACGCTGCTGCGAAGCCAGTATCGACATAG
CAAACCATATTAACCGCCAACAACAACTGGGTATCCCCCAAAGTAGCCGTGATAGCTTTACACTACTTTCACAAAATAAA
ATAATTAATCAGCAGCTTGCAGACAACTTAAAGAAGATGGTTGGCCTAAGAAACATCGCAGTACATGACTATCAAGAACT
CAACCTCGATATCGTTGTGCATGTTGTACAGCATCATCTTGAGGATTTTGAGCAATTTATTGAAGTGATAAAATTTTGTC
CAAGAATGAGTTATTGA
TTGAATGACATTATTATCAACAAAATAGCAACCATCAAACGCTGTATAAAACGCATCCAACAAGTTTATGGTGATGGCAG
CATGTTCAAACAAGACTTCACCCTGCAAGATAGCGTTATCCTCAATTTACAACGCTGCTGCGAAGCCAGTATCGACATAG
CAAACCATATTAACCGCCAACAACAACTGGGTATCCCCCAAAGTAGCCGTGATAGCTTTACACTACTTTCACAAAATAAA
ATAATTAATCAGCAGCTTGCAGACAACTTAAAGAAGATGGTTGGCCTAAGAAACATCGCAGTACATGACTATCAAGAACT
CAACCTCGATATCGTTGTGCATGTTGTACAGCATCATCTTGAGGATTTTGAGCAATTTATTGAAGTGATAAAATTTTGTC
CAAGAATGAGTTATTGA
Antitoxin
Download Length: 207 a.a. Molecular weight: 22650.20 Da Isoelectric Point: 10.2501
>AT197429 WP_209186736.1 NZ_CP072157:125481-126101 [Rhizobium sp. B230/85]
MPSAQDSQKLKLRSLLNERSMMHAHELREAGISAQTIARAVEGGEIDRISRGVYQKRGAEVEENQILAEAIMRAPKGVIA
LVSALAFHGLTDQMPRRVWIAIGTTDWAPVQSYPPLRMVRFTEPYLRQGIEHQVIAGIDVPVYSIPKTLADMFRNPKLVD
RSVAVEGLRAALQQRKATPSAIAQAAKAGGAWKVMQPYLEALTSNG
MPSAQDSQKLKLRSLLNERSMMHAHELREAGISAQTIARAVEGGEIDRISRGVYQKRGAEVEENQILAEAIMRAPKGVIA
LVSALAFHGLTDQMPRRVWIAIGTTDWAPVQSYPPLRMVRFTEPYLRQGIEHQVIAGIDVPVYSIPKTLADMFRNPKLVD
RSVAVEGLRAALQQRKATPSAIAQAAKAGGAWKVMQPYLEALTSNG
Download Length: 621 bp
>AT197429 NZ_CP096166:3061348-3061770 [Shewanella sp. JNE7]
ATGCAACAACTAAATGAAAGCATTATCATCAACTTACTACAAGATAACATCCCGCAGTTGAGATTGATCTACCTATTTGG
CTCCTATGCACAGGGCACGCAACACCGCAACAGTGATATCGATATTGCGGTACTCGCCGATGTCACTTTAGACAATATCG
CCCGCTGGCAACTTGCCCAAAAACTCGCCTCAGCGTTAGATACTGATGTTGATCTTGTTGATTTACGCACGGCATCCACA
GTGTTATGTCAGCAGGTAGTCACCCAAGGAAAGCGACTTTGGGGAACGCGACAAGATGATGAGATTTTTGCAGTGAAAAC
CATCTCAATGTACCAACATCTACAAGCTGAAAGACAAGCAATTATTGATGATGCAACGGCCAAAACAACAGCCAACGATC
ACAGGGGACGTCACTTTGAATGA
ATGCAACAACTAAATGAAAGCATTATCATCAACTTACTACAAGATAACATCCCGCAGTTGAGATTGATCTACCTATTTGG
CTCCTATGCACAGGGCACGCAACACCGCAACAGTGATATCGATATTGCGGTACTCGCCGATGTCACTTTAGACAATATCG
CCCGCTGGCAACTTGCCCAAAAACTCGCCTCAGCGTTAGATACTGATGTTGATCTTGTTGATTTACGCACGGCATCCACA
GTGTTATGTCAGCAGGTAGTCACCCAAGGAAAGCGACTTTGGGGAACGCGACAAGATGATGAGATTTTTGCAGTGAAAAC
CATCTCAATGTACCAACATCTACAAGCTGAAAGACAAGCAATTATTGATGATGCAACGGCCAAAACAACAGCCAACGATC
ACAGGGGACGTCACTTTGAATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|