197426

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 2862749..2863345 Replicon chromosome
Accession NZ_CP072156
Organism Rhizobium sp. B230/85

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag J5289_RS13845 Protein ID WP_209184289.1
Coordinates 2863052..2863345 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag J5289_RS13840 Protein ID WP_209184288.1
Coordinates 2862749..2863051 (-) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J5289_RS29225 2859682..2859867 + 186 WP_247749157.1 BrnT family toxin -
J5289_RS13820 (J5289_13820) 2859833..2860168 + 336 WP_209184285.1 BrnA antitoxin family protein -
J5289_RS13825 (J5289_13825) 2860413..2860589 + 177 WP_209184286.1 hypothetical protein -
J5289_RS13830 (J5289_13830) 2860765..2861217 - 453 WP_142823290.1 GatB/YqeY domain-containing protein -
J5289_RS13835 (J5289_13835) 2861503..2862708 + 1206 WP_209184287.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
J5289_RS13840 (J5289_13840) 2862749..2863051 - 303 WP_209184288.1 putative addiction module antidote protein Antitoxin
J5289_RS13845 (J5289_13845) 2863052..2863345 - 294 WP_209184289.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
J5289_RS13850 (J5289_13850) 2863428..2864834 - 1407 WP_209184290.1 MATE family efflux transporter -
J5289_RS13855 (J5289_13855) 2864981..2866219 - 1239 WP_209184291.1 TCR/Tet family MFS transporter -
J5289_RS13860 (J5289_13860) 2866390..2867301 - 912 WP_209184292.1 LysR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Uncharacterized protein HI1420

(8-97)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11236.07 Da        Isoelectric Point: 10.8212

>T197426 WP_209184289.1 NZ_CP072156:c2863345-2863052 [Rhizobium sp. B230/85]
MPEVRQTILFRRWFDGLKDKRAVERITQRIVRLQAGLFGDIKFFDGIGELRVDHGPGYRVYFVQRGSVLVILLWGGDKSS
QTRDIRKAKAMANDLEI

Download         Length: 294 bp

>T197426 NZ_CP096166:2050299-2050688 [Shewanella sp. JNE7]
ATGGATATCATCTGTTTTCCTTTTGAACGTGTGGTCGAAATTAATGCGTTAATCCTTTCGACAGAGCCCGGCATGAAAGG
TGCGGTTGATATTCCTAAACTTCAGGGAGCGTTGAGCCGTATTGACAATGCGATTGTCTACCAAGGCTTAGATGATGTGT
TTGAGATTGCTGCAAAATACACTGCTTGTATAGCGGTATCTCACGCTTGTCCTGATGCAAATAAGCGAACTGGTTTAGCA
GTAGCACTCGAATACTTATCTCTAAACGACTATGAAATCACAGAGGATAATGAACTGCTAGCGAATGCTATCCGAGACTT
AGTGCTTCAAGAGATTACCGAGACTGACTTTGCTGACATTCTTTATGCTCAGTATCTCAAGGGGTTGTAA

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10352.89 Da        Isoelectric Point: 7.0079

>AT197426 WP_209184288.1 NZ_CP072156:c2863051-2862749 [Rhizobium sp. B230/85]
MPVKTLPFDAADHLQSGQSQLELLSDAFNSGSASYVAVALGVIARAKGMTEVSKTAGITREALYKALSADGDPKLSTLLG
VLNALDLQLKLAPGNKKAPD

Download         Length: 303 bp

>AT197426 NZ_CP096166:2050129-2050299 [Shewanella sp. JNE7]
ATGAATCGAAAATTAGAAGTTTACGGTGTTCAAGTGGTAACTAGACCGAAGATCAAGGCGACCAAACAACTTGATTTATC
AGGTGACTTTGGACGTCAAATCGTTAAGTCAGAAACCAAACTAGCATTAAGAACCCATCCCAAAACTTTCCAAAAGTTGG
CTGATATGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References