Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 1390898..1391378 Replicon chromosome
Accession NZ_CP072156
Organism Rhizobium sp. B230/85

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag J5289_RS06635 Protein ID WP_209183044.1
Coordinates 1391106..1391378 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag J5289_RS06630 Protein ID WP_209187348.1
Coordinates 1390898..1391122 (+) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J5289_RS06595 (J5289_06595) 1386118..1386465 - 348 WP_209183039.1 DUF86 domain-containing protein -
J5289_RS06600 (J5289_06600) 1386466..1386762 - 297 WP_142824229.1 nucleotidyltransferase domain-containing protein -
J5289_RS06605 (J5289_06605) 1386907..1388040 + 1134 WP_209183040.1 site-specific DNA-methyltransferase -
J5289_RS06610 (J5289_06610) 1388155..1388520 - 366 WP_111217840.1 nuclear transport factor 2 family protein -
J5289_RS06615 (J5289_06615) 1388525..1389139 - 615 WP_209183041.1 HAD family phosphatase -
J5289_RS06620 (J5289_06620) 1389156..1390235 - 1080 WP_209183059.1 A/G-specific adenine glycosylase -
J5289_RS06625 (J5289_06625) 1390335..1390835 + 501 WP_209183042.1 DUF721 domain-containing protein -
J5289_RS06630 (J5289_06630) 1390898..1391122 + 225 WP_209187348.1 DUF6290 family protein Antitoxin
J5289_RS06635 (J5289_06635) 1391106..1391378 + 273 WP_209183044.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
J5289_RS06640 (J5289_06640) 1391590..1392285 + 696 WP_209183045.1 DsbA family protein -
J5289_RS06645 (J5289_06645) 1392706..1396164 + 3459 WP_209187349.1 chromosome segregation SMC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-88)

Antitoxin

Relaxosome protein TraY

(4-49)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10710.28 Da        Isoelectric Point: 10.3301

>T197424 WP_209183044.1 NZ_CP072156:1391106-1391378 [Rhizobium sp. B230/85]
MAWRIEFQRPAERDLEKLDHESVKRILRFLHTRVASLEDPRSIGEALRGSELGNFWKYRVGDYRIIADIDDGTVRILVVR
IGNRKDVYRR

Download         Length: 273 bp

>T197424 NZ_CP096166:1210365-1210805 [Shewanella sp. JNE7]
GTGGAAGAGCAGCACCATAGTTTCAGCGTAAAAGCCTCCTTCGACCAACGGCTCTCGTTGGTCGTTTTTATGTGCGTTTG
TTCCTCATCATTCCTTATTTGGCCTTATACAGAACATTGGTTAGTGACGCTGCTACGGCTTGGATTGTTTTTGTTATCCG
TTAGCTTTTTGATATGGCAATTGTGGAGGCTTAAGGACTGGCGTTTAAGCTTTATGCTTAATGGTAAAGGTGACGGTCGA
TTATCCACGGGAGAACATTTCAGAATTTTAAGGCGCACATGGGTTACCCCATTTGTATGTATGATATACATCGATGTTGA
AGAAAATACGCGTTTAGTATTGCTTTGGGCCGATATGTTTACGGGTGTTGACTATAGACATTTATGCCGATTATTGCTTA
AGGCTAAAATGCTGCAAGCTAAATCTCAGGTTGAAATTTAG

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8542.61 Da        Isoelectric Point: 4.5355

>AT197424 WP_209187348.1 NZ_CP072156:1390898-1391122 [Rhizobium sp. B230/85]
MLALRLPPDIEARLDELAKRTGRSKSFYARQAILEHLDDLEDLYVAEQRLEEFRRGDSDSISLAELMARHGVED

Download         Length: 225 bp

>AT197424 NZ_CP096166:1210136-1210384 [Shewanella sp. JNE7]
TTGGAATTAATGAATATTGCACGGGTTCGTTGGGCATGTCGTCGTGGAATGTTGGAATTGGATGTGCTGTTTCAACCTTT
CGTCGAGAATATTTATCAAGATTTGTCAGATATAGATAAAGCATCGTTTATTCGATTATTAGAATGTGAAGATCCTGAGT
TGTTTGCTTGGTTTATGGGGCATGAAGCCTGTCCTGATGCAGAGCTAGCTCGCATGGTTGTTAAAGTTCGTGGAAGAGCA
GCACCATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References