197420

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 1615158..1615738 Replicon chromosome
Accession NZ_CP072152
Organism Rhizobium sp. K15/93

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag J5280_RS26035 Protein ID WP_209185942.1
Coordinates 1615158..1615541 (-) Length 128 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag J5280_RS26040 Protein ID WP_142831764.1
Coordinates 1615538..1615738 (-) Length 67 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J5280_RS26020 (J5280_26015) 1612070..1612543 - 474 Protein_1495 FCD domain-containing protein -
J5280_RS26025 (J5280_26020) 1613088..1613831 - 744 WP_209185940.1 hypothetical protein -
J5280_RS26030 (J5280_26025) 1613815..1614888 - 1074 WP_209185941.1 AAA family ATPase -
J5280_RS26035 (J5280_26030) 1615158..1615541 - 384 WP_209185942.1 type II toxin-antitoxin system VapC family toxin Toxin
J5280_RS26040 (J5280_26035) 1615538..1615738 - 201 WP_142831764.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
J5280_RS26045 (J5280_26040) 1615869..1616873 - 1005 WP_209185988.1 C-terminal binding protein -
J5280_RS26050 (J5280_26045) 1616878..1617849 - 972 WP_209185943.1 2-dehydropantoate 2-reductase N-terminal domain-containing protein -
J5280_RS26055 (J5280_26050) 1617862..1619043 - 1182 WP_209185944.1 acyl-CoA dehydrogenase family protein -
J5280_RS26060 (J5280_26055) 1619163..1620266 - 1104 WP_209185945.1 LLM class flavin-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-113)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-42)


Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 13994.23 Da        Isoelectric Point: 9.0165

>T197420 WP_209185942.1 NZ_CP072152:c1615541-1615158 [Rhizobium sp. K15/93]
VILVDTSIWIDHFRHGDVELRKVIADDRLLCHPVVVGELALGSLRDRGAVMAFFSAQREALVASHYEVITMIGRHSIFSM
GIGYTDAHLLASILLDRRSLLWTRDKRLAAAARKAGASLYAPTSAPN

Download         Length: 384 bp

>T197420 NZ_CP096163:c4622955-4622017 [Shewanella sp. JNE10-2]
ATGGATAAAGATAGCCCATATTACAAACAGGTTTCCTTGCTCATAAGAATGCTTCCTGTGGTAGCAACAGAGACGGTTTT
TGCACTTAAAGGTGGCACCGCCATTAATTTATTTGTGAGAGATTTTCCTCGGTTATCTGTAGATATTGATCTTGCTTATC
TTCCACTTGAACCAAGAGATGAGGCTTTGATTAATGTCAGGGCTGCATTGCAGCGCATTACAGACAGAATCAATACTCAA
CCAGATATCAGAGCGGCATTTCAGGATAATAAAGCTGATGAACTGAGAATAGTTGTATCAAGTCCGGTTGCGACGATCAA
AATTGAAGTGTCGCCCGTCGCCAGAGGTACATTGCATAGTGCAGAAATAATGCCAGTTCAAGAGTCTGTTGAAGACGAGT
TTGGTTATGCTGAGATTCAGGTAGTCAGTCTTCCCGATCTGTATGGTGGGAAATTGTGTGCTGCAATGGATCGCCAACAT
CCTCGCGACTTATTTGATGTGCGTATGTTACTTGGCAGTGAAGGGATTTCGAGAGAGATTTTGGTGGGTTTTTTAACCTA
TACATTAAGTCACCCTCGGCCTATTAATGAAGTCATGTCGCCAAACTGGCAGCCTCTGAATGAGAAATTTCAGGCAGAAT
TTGACGGAATGACTTTTGAAAAAGTTGAATGCGAAGACTTAGCCTCTGTTAGGCCCATGATGTTAATTGAGCTGCAAAAA
CATTTCACAGAAAGGGATCATGCTTTCCTTATGTCATTCAAAAGAGGGCAACCTGACTGGGCATTGTTTGACTATCCTAA
TGCAGCAGACTTGCCAGCGATTCGTTGGAAATTGCAGAACATTAACAAATTGGCAAAGAATCAAGCAAAACACCAAGAGC
AATTAGATAAATTGAAGCAAGTGCTTGATGATTGGCTTGTTAACGCAAACGCCGAGTAA

Antitoxin


Download         Length: 67 a.a.        Molecular weight: 7125.13 Da        Isoelectric Point: 10.4525

>AT197420 WP_142831764.1 NZ_CP072152:c1615738-1615538 [Rhizobium sp. K15/93]
MRSTINLDDNLMEQARSLTGTKETAALVRQALETLVRVESGKRLAALGGTMPDAEAAPRRRSEAAK

Download         Length: 201 bp

>AT197420 NZ_CP096163:c4623739-4622948 [Shewanella sp. JNE10-2]
ATGTCATCTAAGATAAACTGGCTTGTTGCTCATACTTCTCCTGGTGCGCTAGTACTTCAGCAATGGCTGACTGAAAACGG
TGTGAGCTACTCCCTGGCTCAAAAGTACGCGCAGAACGGTTGGCTGAAGAAGCTTAGTTCTGGCGTGTACTATCGTCCAG
ATGCGCAGGGCGATATAAAGCCAACTTGGGTTGATGCCATTCAAGCATTAGATGTGCAATTGGGCGTTTCAGTTCATTTG
GCTGGATTGAGCAGCTTAACTCACCAAGGACTGAGTCACTATTTACAGCTGAACAAAGAGCAAGTTTGGATTTGCGTTAA
AAATAAGTCGTCCTTACCAAAATGGTTTCGTGAATTCCCTTATCAGAATTGGTTTTACTGTGGAAACCATAAGCTTGAAG
TGAATCCCGAGAAAGATTTGAAAAGGATCACGGTTAAAGAGAAAGAACTCACTGTCAGCTGTGCAGAACTTGCTGCCTAT
GAAGTGGTAGACGCGATTGGGAAGCTGATTTCATTTGAGCATGTCGCAGAATTATTTCAGGGTTTAGTCAATCTTAGCCC
TAGAAAAGTACAAGATATTCTTGAGCGAAGCAGCTCTGTTCAGGCAAACCGAATATTTCTATTTCTGGGTCGATACTACG
ATCACCAGTGGGTCAATCGCATAGATGAAACAAGAATTAAATTGGGGGCAGGAAAGCGGCAGGTTGTCGAAAAAGGACGT
TTTGATGAGCGATATCAAATCACAGTGCCAGAGATATTAAGCGTCAAAAAAGGTGAACAACATAATGGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References