Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | rlegTA/AbiEii-AbiEi |
| Location | 1446697..1448188 | Replicon | chromosome |
| Accession | NZ_CP072152 | ||
| Organism | Rhizobium sp. K15/93 | ||
Toxin (Protein)
| Gene name | rlegT | Uniprot ID | - |
| Locus tag | J5280_RS25310 | Protein ID | WP_209186735.1 |
| Coordinates | 1447310..1448188 (+) | Length | 293 a.a. |
Antitoxin (Protein)
| Gene name | rlegA | Uniprot ID | - |
| Locus tag | J5280_RS25305 | Protein ID | WP_209186736.1 |
| Coordinates | 1446697..1447317 (+) | Length | 207 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| J5280_RS25285 (J5280_25280) | 1442351..1443157 | - | 807 | WP_209186740.1 | molybdate ABC transporter substrate-binding protein | - |
| J5280_RS25290 (J5280_25285) | 1443171..1443944 | - | 774 | WP_209186739.1 | ABC transporter ATP-binding protein | - |
| J5280_RS25295 (J5280_25290) | 1443941..1444975 | - | 1035 | WP_209186738.1 | iron ABC transporter permease | - |
| J5280_RS25300 (J5280_25295) | 1444972..1445979 | - | 1008 | WP_247749309.1 | ABC transporter substrate-binding protein | - |
| J5280_RS25305 (J5280_25300) | 1446697..1447317 | + | 621 | WP_209186736.1 | AbiEi antitoxin N-terminal domain-containing protein | Antitoxin |
| J5280_RS25310 (J5280_25305) | 1447310..1448188 | + | 879 | WP_209186735.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
| J5280_RS32005 | 1448198..1448320 | + | 123 | WP_257623455.1 | hypothetical protein | - |
| J5280_RS32010 | 1448727..1448930 | + | 204 | WP_247748920.1 | EthD domain-containing protein | - |
| J5280_RS25320 (J5280_25315) | 1449220..1450434 | - | 1215 | WP_219258769.1 | IS701 family transposase | - |
| J5280_RS25330 (J5280_25325) | 1451658..1451921 | + | 264 | WP_257623454.1 | inositol monophosphatase family protein | - |
| J5280_RS25335 (J5280_25330) | 1452215..1452799 | + | 585 | WP_209186535.1 | sigma-70 family RNA polymerase sigma factor | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 293 a.a. Molecular weight: 32674.48 Da Isoelectric Point: 5.2868
>T197419 WP_209186735.1 NZ_CP072152:1447310-1448188 [Rhizobium sp. K15/93]
MAKTPANMAKSVKDRLLNIARKESRAFDVLLVRFALERLLYRLSISAHRDRFVLKGGMLVTVWVADDNRVTRDADFLGHG
DADPARLIADFGEIMAIESDDGLAFDIDALAATTIREEMEYGGVRLRTAAYLERTRISVTIDIGFGDAMADATQRLDYPA
LLDFPAPQVRSYPPATVIAEKFQAMVALGVLNGRMKDYYDLWAIPRAIDIPADDLDAAIRVTFERRRTPIPRERPPGLSV
EMFSDEGKQRQWRAYAASLELEAVSLESIIGRVWELIGPSCARIVARNDNKT
MAKTPANMAKSVKDRLLNIARKESRAFDVLLVRFALERLLYRLSISAHRDRFVLKGGMLVTVWVADDNRVTRDADFLGHG
DADPARLIADFGEIMAIESDDGLAFDIDALAATTIREEMEYGGVRLRTAAYLERTRISVTIDIGFGDAMADATQRLDYPA
LLDFPAPQVRSYPPATVIAEKFQAMVALGVLNGRMKDYYDLWAIPRAIDIPADDLDAAIRVTFERRRTPIPRERPPGLSV
EMFSDEGKQRQWRAYAASLELEAVSLESIIGRVWELIGPSCARIVARNDNKT
Download Length: 879 bp
>T197419 NZ_CP096163:4252723-4253139 [Shewanella sp. JNE10-2]
TTGAATGACATTATTATCAACAAAATAGCAACCATCAAACGCTGTATAAAACGCATCCAACAAGTTTATGGTGATGGCAG
CATGTTCAAACAAGACTTCACCCTGCAAGATAGCGTTATCCTCAATTTACAACGCTGCTGCGAAGCCAGTATCGACATAG
CAAACCATATTAACCGCCAACAACAACTGGGTATCCCCCAAAGTAGCCGTGATAGCTTTACACTACTTTCACAAAATAAA
ATAATTAATCAGCAGCTTGCAGACAACTTAAAGAAGATGGTTGGCCTAAGAAACATCGCAGTACATGACTATCAAGAACT
CAACCTCGATATCGTTGTGCATGTTGTACAGCATCATCTTGAGGATTTTGAGCAATTTATTGAAGTGATAAAATTTTGTC
CAAGAATGAGTTATTGA
TTGAATGACATTATTATCAACAAAATAGCAACCATCAAACGCTGTATAAAACGCATCCAACAAGTTTATGGTGATGGCAG
CATGTTCAAACAAGACTTCACCCTGCAAGATAGCGTTATCCTCAATTTACAACGCTGCTGCGAAGCCAGTATCGACATAG
CAAACCATATTAACCGCCAACAACAACTGGGTATCCCCCAAAGTAGCCGTGATAGCTTTACACTACTTTCACAAAATAAA
ATAATTAATCAGCAGCTTGCAGACAACTTAAAGAAGATGGTTGGCCTAAGAAACATCGCAGTACATGACTATCAAGAACT
CAACCTCGATATCGTTGTGCATGTTGTACAGCATCATCTTGAGGATTTTGAGCAATTTATTGAAGTGATAAAATTTTGTC
CAAGAATGAGTTATTGA
Antitoxin
Download Length: 207 a.a. Molecular weight: 22650.20 Da Isoelectric Point: 10.2501
>AT197419 WP_209186736.1 NZ_CP072152:1446697-1447317 [Rhizobium sp. K15/93]
MPSAQDSQKLKLRSLLNERSMMHAHELREAGISAQTIARAVEGGEIDRISRGVYQKRGAEVEENQILAEAIMRAPKGVIA
LVSALAFHGLTDQMPRRVWIAIGTTDWAPVQSYPPLRMVRFTEPYLRQGIEHQVIAGIDVPVYSIPKTLADMFRNPKLVD
RSVAVEGLRAALQQRKATPSAIAQAAKAGGAWKVMQPYLEALTSNG
MPSAQDSQKLKLRSLLNERSMMHAHELREAGISAQTIARAVEGGEIDRISRGVYQKRGAEVEENQILAEAIMRAPKGVIA
LVSALAFHGLTDQMPRRVWIAIGTTDWAPVQSYPPLRMVRFTEPYLRQGIEHQVIAGIDVPVYSIPKTLADMFRNPKLVD
RSVAVEGLRAALQQRKATPSAIAQAAKAGGAWKVMQPYLEALTSNG
Download Length: 621 bp
>AT197419 NZ_CP096163:4252308-4252730 [Shewanella sp. JNE10-2]
ATGCAACAACTAAATGAAAGCATTATCATCAACTTACTACAAGATAACATCCCGCAGTTGAGATTGATCTACCTATTTGG
CTCCTATGCACAGGGCACGCAACACCGCAACAGTGATATCGATATTGCGGTACTCGCCGATGTCACTTTAGACAATATCG
CCCGCTGGCAACTTGCCCAAAAACTCGCCTCAGCGTTAGATACTGATGTTGATCTTGTTGATTTACGCACGGCATCCACA
GTGTTATGTCAGCAGGTAGTCACCCAAGGAAAGCGACTTTGGGGAACGCGACAAGATGATGAGATTTTTGCAGTGAAAAC
CATCTCAATGTACCAACATCTACAAGCTGAAAGACAAGCAATTATTGATGATGCAACGGCCAAAACAACAGCCAACGATC
ACAGGGGACGTCACTTTGAATGA
ATGCAACAACTAAATGAAAGCATTATCATCAACTTACTACAAGATAACATCCCGCAGTTGAGATTGATCTACCTATTTGG
CTCCTATGCACAGGGCACGCAACACCGCAACAGTGATATCGATATTGCGGTACTCGCCGATGTCACTTTAGACAATATCG
CCCGCTGGCAACTTGCCCAAAAACTCGCCTCAGCGTTAGATACTGATGTTGATCTTGTTGATTTACGCACGGCATCCACA
GTGTTATGTCAGCAGGTAGTCACCCAAGGAAAGCGACTTTGGGGAACGCGACAAGATGATGAGATTTTTGCAGTGAAAAC
CATCTCAATGTACCAACATCTACAAGCTGAAAGACAAGCAATTATTGATGATGCAACGGCCAAAACAACAGCCAACGATC
ACAGGGGACGTCACTTTGAATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|