197413

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 1981940..1982420 Replicon chromosome
Accession NZ_CP072151
Organism Rhizobium sp. K15/93

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag J5280_RS09685 Protein ID WP_209183044.1
Coordinates 1981940..1982212 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag J5280_RS09690 Protein ID WP_209183043.1
Coordinates 1982196..1982420 (-) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J5280_RS09675 (J5280_09670) 1977154..1980612 - 3459 WP_209183046.1 chromosome segregation SMC family protein -
J5280_RS09680 (J5280_09675) 1981033..1981728 - 696 WP_209183045.1 DsbA family protein -
J5280_RS09685 (J5280_09680) 1981940..1982212 - 273 WP_209183044.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
J5280_RS09690 (J5280_09685) 1982196..1982420 - 225 WP_209183043.1 DUF6290 family protein Antitoxin
J5280_RS09695 (J5280_09690) 1982483..1982983 - 501 WP_209183042.1 DUF721 domain-containing protein -
J5280_RS09700 (J5280_09695) 1983083..1984162 + 1080 WP_209183059.1 A/G-specific adenine glycosylase -
J5280_RS09705 (J5280_09700) 1984179..1984793 + 615 WP_209183041.1 HAD family phosphatase -
J5280_RS09710 (J5280_09705) 1984798..1985163 + 366 WP_111217840.1 nuclear transport factor 2 family protein -
J5280_RS09715 (J5280_09710) 1985278..1986411 - 1134 WP_209183040.1 site-specific DNA-methyltransferase -
J5280_RS09720 (J5280_09715) 1986556..1986852 + 297 WP_142824229.1 nucleotidyltransferase domain-containing protein -
J5280_RS09725 (J5280_09720) 1986853..1987200 + 348 WP_209183039.1 DUF86 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-88)

Antitoxin

Relaxosome protein TraY

(4-47)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10710.28 Da        Isoelectric Point: 10.3301

>T197413 WP_209183044.1 NZ_CP072151:c1982212-1981940 [Rhizobium sp. K15/93]
MAWRIEFQRPAERDLEKLDHESVKRILRFLHTRVASLEDPRSIGEALRGSELGNFWKYRVGDYRIIADIDDGTVRILVVR
IGNRKDVYRR

Download         Length: 273 bp

>T197413 NZ_CP096163:c1488772-1488473 [Shewanella sp. JNE10-2]
ATGAAAAATAAACGCTATAAACTGAGTAAGTTAGCTCAAACTCACTTACTAAAGATTAAAGACTACACCATTCAACACTT
TTCTGAGTCGCAGTGGCACAAATACAAAGAAAGCCTAATATCCGGCTTGCAAATGTTAGCCGATAACCCCGGATTAGGCA
GAAGCTGCGAAGATATTTACCCCAACGGATTCTACTTTCCGATTGCTAAACACACCGCCTACTTCACAAAAGAAGACGAC
TTCATCCTCATCGTTGCCCTGTTAGGCCAGCCACAACTACCACAAAATCATCTGAAATAG

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8517.61 Da        Isoelectric Point: 4.4056

>AT197413 WP_209183043.1 NZ_CP072151:c1982420-1982196 [Rhizobium sp. K15/93]
MLALRLPPDIEARLDELAKRTGRSKSFYARQAILEHLDDLEDLYVAEQMLEEFRRGDSDSISLAELMARHGVED

Download         Length: 225 bp

>AT197413 NZ_CP096163:c1489023-1488781 [Shewanella sp. JNE10-2]
GTGCAAACATTAACAGCCAATGACGCCAAACGAAATTTCGGTGAGTTACTGCTAAACGCTCAACGTGAACCCATCAAGAT
CAGCAAAAACAGTAAAGATGCGGTTGTTGTGATGTCTATTCACGACTTCGAACAACTTGAGGCGATGAAAGCGGATTACC
TTAAACACTGCTTCAACGCTGCTAAAGAAGACTTAGCGAAAGGTAATATTGTTGATGGTGAAGATTTTCTTAACGCCCTG
TAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References