197412

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/HTH_26(antitoxin)
Location 1896626..1897240 Replicon chromosome
Accession NZ_CP072151
Organism Rhizobium sp. K15/93

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag J5280_RS09255 Protein ID WP_209183151.1
Coordinates 1896995..1897240 (-) Length 82 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag J5280_RS09250 Protein ID WP_209187356.1
Coordinates 1896626..1896988 (-) Length 121 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J5280_RS09225 (J5280_09215) 1891850..1892104 - 255 WP_209183157.1 type II toxin-antitoxin system ParD family antitoxin -
J5280_RS09230 (J5280_09220) 1892306..1892854 - 549 WP_209183156.1 HdeD family acid-resistance protein -
J5280_RS09235 (J5280_09225) 1893024..1893623 + 600 WP_209183155.1 transcriptional regulator BetI -
J5280_RS09240 (J5280_09230) 1893620..1895149 + 1530 WP_209183154.1 choline-sulfatase -
J5280_RS09245 (J5280_09235) 1895151..1896614 + 1464 WP_209183153.1 betaine-aldehyde dehydrogenase -
J5280_RS09250 (J5280_09240) 1896626..1896988 - 363 WP_209187356.1 helix-turn-helix transcriptional regulator Antitoxin
J5280_RS09255 (J5280_09245) 1896995..1897240 - 246 WP_209183151.1 cytotoxic translational repressor of toxin-antitoxin stability system Toxin
J5280_RS09260 (J5280_09250) 1897334..1898986 + 1653 WP_209183150.1 choline dehydrogenase -
J5280_RS09265 (J5280_09255) 1899014..1900072 - 1059 WP_209183149.1 LacI family DNA-binding transcriptional regulator -
J5280_RS09270 (J5280_09260) 1900627..1900926 - 300 WP_209183148.1 type II toxin-antitoxin system RelE/ParE family toxin -
J5280_RS09275 (J5280_09265) 1900923..1901198 - 276 WP_209183147.1 YlcI/YnfO family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(67-114)


Sequences

Toxin        


Download         Length: 82 a.a.        Molecular weight: 9209.05 Da        Isoelectric Point: 10.9851

>T197412 WP_209183151.1 NZ_CP072151:c1897240-1896995 [Rhizobium sp. K15/93]
MKDVVVSRLADKALMRMQPKRRLAIIEKVKAYARGEIVDIKKMKGGNLYRIRVGQDRVIIDDKGRIVVVIDAGPRGSIYK
E

Download         Length: 246 bp

>T197412 NZ_CP096163:c998417-998211 [Shewanella sp. JNE10-2]
GTGAGTTATTCCAAAATTTTCAAAGAATTGGATAAATCACTACACGATAGAGCATCATTTGACTGTGGCGAAGCAGAGTT
AAACGATTTTATCCAAACTCAAGCAGCAAAACATATGCAAGCAGGTATTAGCCGTACAATGGCGGCGTTTTTCAAGCTAG
TTGTCACCATCGACCGTTTTAAGCGGCCTTTTTTTCCACTTCTTTAA

Antitoxin


Download         Length: 121 a.a.        Molecular weight: 13066.79 Da        Isoelectric Point: 4.3246

>AT197412 WP_209187356.1 NZ_CP072151:c1896988-1896626 [Rhizobium sp. K15/93]
MGDIKRFEIDGKPYVLLSEEDYEDLVDGLRANAVLAGISAGEETWPLEIVEARANGGNAVRIFRNYRRMTVTELATAAGI
SQPYLSEIEAGKKTGSVDVLKRIANALKVDLDDLVVNVAD

Download         Length: 363 bp

>AT197412 NZ_CP096163:c998683-998414 [Shewanella sp. JNE10-2]
ATGGCGACTGCAAGACTTGATATCCGTTTGGATGAAGAAATCAAAGCTAAGGCTGAGAAAGCATCCGCTTTGCTCGGGTT
AAAAAGCTTAACTGAATACGTTGTTCGCTTAATGGACGAAGATGCAACTCAGGTGATAGCTGAGCATGAAAGCGTTACGG
TTAAAGCAGATGTATTCGACCAATTCATAATGGCTTGTGATGAGGCTAAGGTTCCGAATAAGGCATTGCGTGAAGCGGCT
GCATTTACTAAAAATGGTGAGTTTAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References