197411

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 518062..518658 Replicon chromosome
Accession NZ_CP072151
Organism Rhizobium sp. K15/93

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag J5280_RS02455 Protein ID WP_209184289.1
Coordinates 518062..518355 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag J5280_RS02460 Protein ID WP_209184288.1
Coordinates 518356..518658 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J5280_RS02440 (J5280_02430) 514106..515017 + 912 WP_209184292.1 LysR family transcriptional regulator -
J5280_RS02445 (J5280_02435) 515188..516426 + 1239 WP_209184291.1 TCR/Tet family MFS transporter -
J5280_RS02450 (J5280_02440) 516573..517979 + 1407 WP_209184290.1 MATE family efflux transporter -
J5280_RS02455 (J5280_02445) 518062..518355 + 294 WP_209184289.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
J5280_RS02460 (J5280_02450) 518356..518658 + 303 WP_209184288.1 putative addiction module antidote protein Antitoxin
J5280_RS02465 (J5280_02455) 518699..519904 - 1206 WP_209184287.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
J5280_RS02470 (J5280_02460) 520190..520642 + 453 WP_142823290.1 GatB/YqeY domain-containing protein -
J5280_RS02475 (J5280_02465) 520818..520994 - 177 WP_209184286.1 hypothetical protein -
J5280_RS02480 (J5280_02470) 521239..521574 - 336 WP_209184285.1 BrnA antitoxin family protein -
J5280_RS31665 521540..521725 - 186 WP_247749157.1 BrnT family toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Uncharacterized protein HI1420

(8-97)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11236.07 Da        Isoelectric Point: 10.8212

>T197411 WP_209184289.1 NZ_CP072151:518062-518355 [Rhizobium sp. K15/93]
MPEVRQTILFRRWFDGLKDKRAVERITQRIVRLQAGLFGDIKFFDGIGELRVDHGPGYRVYFVQRGSVLVILLWGGDKSS
QTRDIRKAKAMANDLEI

Download         Length: 294 bp

>T197411 NZ_CP096160:24893-25234 [Listeria monocytogenes]
ATGGTAAAGCAAGGCGATATTATCAAGATCAATCTAAATCCAAAACAGGGACACGAGCAGCAAGGCTATCGGCCCTATAT
TTGCCTCAGTCATCATCTGGTAAGTGATTATGCAAATATCGCGATCTTTGCCCCAATCAGTAATACACCGCGCACCTATC
CGTTATATGTGCCTTTGACAGGGACAACCACAACCGGAAAAGTATTGCTGGATCAACTAGTTACGATCGATTACAACGCT
CGTAAGCATCAATACGTGGAAACTGTTTCGGATCCATTGCTCACAAAGCTATTAGATACAGTAAAAGTTATTTTTCAAAA
GAACGAGAGATCAACCAACTAA

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10352.89 Da        Isoelectric Point: 7.0079

>AT197411 WP_209184288.1 NZ_CP072151:518356-518658 [Rhizobium sp. K15/93]
MPVKTLPFDAADHLQSGQSQLELLSDAFNSGSASYVAVALGVIARAKGMTEVSKTAGITREALYKALSADGDPKLSTLLG
VLNALDLQLKLAPGNKKAPD

Download         Length: 303 bp

>AT197411 NZ_CP096160:24657-24899 [Listeria monocytogenes]
ATGACCACCGTTAGCGTTAAAAAGTGGGGAAATAGCAAAGCTGTTCGTCTCCCCAATAATCTATTAAATGCCTTAGACAT
CAAAGAGAACGATGATTTGAAAGTGGAAGTGATCAATAATCAGATGATCCTTACCAAAACAGCTATCGATCTCCGAATCG
AGGATCTGTTTGCCAATTACCAGGGCGAACCCTTCCAAACTGAGCTGCAAACATTCGAACCAATCGGAGATGAAAAATGG
TAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References