Detailed information of TA system TA197410

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /BrnT(toxin)
• Location: 423190..423667
• Replicon: chromosome
• Accession: NZ_CP072151
• Organism: Rhizobium sp. K15/93

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: J5280_RS02000
• Protein ID: WP_209184349.1
• Coordinates: 423190..423453 (+)
• Length: 88 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: J5280_RS02005
• Protein ID: WP_209184348.1
• Coordinates: 423440..423667 (+)
• Length: 76 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
J5280_RS01975 (J5280_01970)	418679..419359	-	681	WP_209184352.1	GNAT family N-acetyltransferase	-
J5280_RS01980 (J5280_01975)	419568..420032	+	465	WP_142823372.1	preQ(1) synthase	-
J5280_RS01985 (J5280_01980)	420096..420914	-	819	WP_209184351.1	DUF2076 domain-containing protein	-
J5280_RS01990 (J5280_01985)	421144..421728	+	585	WP_142823370.1	ATP-dependent Clp protease proteolytic subunit	-
J5280_RS01995 (J5280_01990)	421963..423153	+	1191	WP_209184350.1	benzoate/H(+) symporter BenE family transporter	-
J5280_RS02000 (J5280_01995)	423190..423453	+	264	WP_209184349.1	BrnT family toxin	Toxin
J5280_RS02005 (J5280_02000)	423440..423667	+	228	WP_209184348.1	CopG family transcriptional regulator	Antitoxin
J5280_RS02010 (J5280_02005)	424038..425780	+	1743	WP_209184347.1	2-isopropylmalate synthase	-
J5280_RS02015 (J5280_02010)	425860..426693	-	834	WP_209184592.1	anti-sigma factor	-
J5280_RS02020 (J5280_02015)	426696..427208	-	513	WP_209184346.1	RNA polymerase sigma factor	-
J5280_RS02025 (J5280_02020)	427525..428433	-	909	WP_111222671.1	metallophosphoesterase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (5-80)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 88 a.a.
• Molecular weight: 10153.67 Da
• Isoelectric Point: 10.5475

>T197410 WP_209184349.1 NZ_CP072151:423190-423453 [Rhizobium sp. K15/93]
MAFEFDPDKSRTNKIKHGIDLVEAQRLWIDRFLISFPARGGLESRFVAVGQIDGKHWSAICTRRHDNIRIISVRRSRKEE
IALYEGK

Nucleotide

• Length: 264 bp

>T197410 NZ_CP096148:2106622-2106969 [Listeria innocua]
CTGATGGTGAAGCGTGGTGACGTTTACTACGCGGACCTTTCCCCCGTGGTCGGAAGCGAGCAAGGGGGAATAAGGCCTGT
TCTCATCATTCAAAATGATATTGGTAATAGATTCAGTCCAACTGTGATCGTGGCAGCAATAACTGCAAAAATTCAAAAAG
CGAAGTTGCCAACACATGTGGAAGCTACTCGTAAAGACGGCTTTGAAAGAGATTCTGTCATTCTATTAGAACAAATTAGA
ACGATAGATAAACAACGCCTGACAGATAAGATTACACATTTGGACGAGGAACTAATGGCCAAGGTAAATCAGGCACTTGA
AGTCAGTCTAGGAGTAGTAGAATTCTAA

Antitoxin

Protein

• Length: 76 a.a.
• Molecular weight: 8402.36 Da
• Isoelectric Point: 4.0813

>AT197410 WP_209184348.1 NZ_CP072151:423440-423667 [Rhizobium sp. K15/93]
MKASELDEKFDNGEDILDYLDLTKATRPNMATQKVSVDFATSVVNSLDEEAARLGLTRQSLINLWIEERLSAAQD

Nucleotide

• Length: 228 bp

>AT197410 NZ_CP096148:2106340-2106618 [Listeria innocua]
GTGTTAGAGAAAGAAAAACGGATGATAATATCCGTAGAACTGACACAGGAAATGGTACAAGAACTCGACGTAGTTGTAGA
AAAAGAAAAAATGGGGCGGAGTGAAGTTATAATGGAAGCAACGCAACAATTTTTACAGGAGAAAAGAGCTCGTGAATTAA
GAGACGAGATGGAACGCGGCTATGCAGAAATGGCGACGATTAATTTCGCTATCGCGTGCGAGTGTACTCATGTCGAAGCA
GAGGCAGAAGACAGGAATATTAGTATTTTAGGAGGTTAA