Detailed information of TA system TA197408

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): rlegTA/AbiEii-AbiEi
• Location: 1153221..1154712
• Replicon: chromosome
• Accession: NZ_CP072147
• Organism: Rhizobium sp. K1/93

Toxin (Protein)

• Gene name: rlegT
• Uniprot ID: -
• Locus tag: J5287_RS23905
• Protein ID: WP_209186735.1
• Coordinates: 1153221..1154099 (-)
• Length: 293 a.a.

Antitoxin (Protein)

• Gene name: rlegA
• Uniprot ID: -
• Locus tag: J5287_RS23910
• Protein ID: WP_209186736.1
• Coordinates: 1154092..1154712 (-)
• Length: 207 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
J5287_RS23880 (J5287_23860)	1148610..1149194	-	585	WP_209186535.1	sigma-70 family RNA polymerase sigma factor	-
J5287_RS23885 (J5287_23865)	1149488..1149751	-	264	WP_257623454.1	inositol monophosphatase family protein	-
J5287_RS23890 (J5287_23870)	1150151..1150929	+	779	WP_257623478.1	IS5 family transposase	-
J5287_RS23895 (J5287_23875)	1150975..1152189	+	1215	WP_219258769.1	IS701 family transposase	-
J5287_RS31930	1152479..1152682	-	204	WP_247748920.1	EthD domain-containing protein	-
J5287_RS31935	1153089..1153211	-	123	WP_257623455.1	hypothetical protein	-
J5287_RS23905 (J5287_23885)	1153221..1154099	-	879	WP_209186735.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
J5287_RS23910 (J5287_23890)	1154092..1154712	-	621	WP_209186736.1	AbiEi antitoxin N-terminal domain-containing protein	Antitoxin
J5287_RS23915 (J5287_23895)	1155430..1156437	+	1008	WP_247749309.1	ABC transporter substrate-binding protein	-
J5287_RS23920 (J5287_23900)	1156515..1157468	+	954	WP_257623480.1	iron ABC transporter permease	-
J5287_RS23925 (J5287_23905)	1157465..1158238	+	774	WP_209186739.1	ABC transporter ATP-binding protein	-
J5287_RS23930 (J5287_23910)	1158252..1159058	+	807	WP_209186740.1	molybdate ABC transporter substrate-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (38-261)

Antitoxin

• Transcriptional regulator AbiEi antitoxin, N-terminal domain (12-92)

Sequences

Toxin

Protein

• Length: 293 a.a.
• Molecular weight: 32674.48 Da
• Isoelectric Point: 5.2868

>T197408 WP_209186735.1 NZ_CP072147:c1154099-1153221 [Rhizobium sp. K1/93]
MAKTPANMAKSVKDRLLNIARKESRAFDVLLVRFALERLLYRLSISAHRDRFVLKGGMLVTVWVADDNRVTRDADFLGHG
DADPARLIADFGEIMAIESDDGLAFDIDALAATTIREEMEYGGVRLRTAAYLERTRISVTIDIGFGDAMADATQRLDYPA
LLDFPAPQVRSYPPATVIAEKFQAMVALGVLNGRMKDYYDLWAIPRAIDIPADDLDAAIRVTFERRRTPIPRERPPGLSV
EMFSDEGKQRQWRAYAASLELEAVSLESIIGRVWELIGPSCARIVARNDNKT

Nucleotide

• Length: 879 bp

>T197408 NZ_CP096143:2334692-2334844 [Xanthomonas prunicola]
ATGAAGCGACTGCTGACACTGATGGTACTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACATGCAGGGCGCAGGTGGGAAGGTCGAGAAAACCGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Antitoxin

Protein

• Length: 207 a.a.
• Molecular weight: 22650.20 Da
• Isoelectric Point: 10.2501

>AT197408 WP_209186736.1 NZ_CP072147:c1154712-1154092 [Rhizobium sp. K1/93]
MPSAQDSQKLKLRSLLNERSMMHAHELREAGISAQTIARAVEGGEIDRISRGVYQKRGAEVEENQILAEAIMRAPKGVIA
LVSALAFHGLTDQMPRRVWIAIGTTDWAPVQSYPPLRMVRFTEPYLRQGIEHQVIAGIDVPVYSIPKTLADMFRNPKLVD
RSVAVEGLRAALQQRKATPSAIAQAAKAGGAWKVMQPYLEALTSNG

Nucleotide

• Length: 621 bp

>AT197408 NZ_CP096143:2334919-2335053 [Xanthomonas prunicola]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTCGGTATGCTGTCGGGCTGCAACACCGTCGCAGGTGC
TGGCAAGGACGTGAAGGGTGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA