Detailed information of TA system TA197407

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-VapB
• Location: 985669..986249
• Replicon: chromosome
• Accession: NZ_CP072147
• Organism: Rhizobium sp. K1/93

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: J5287_RS23180
• Protein ID: WP_209185942.1
• Coordinates: 985866..986249 (+)
• Length: 128 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: J5287_RS23175
• Protein ID: WP_142831764.1
• Coordinates: 985669..985869 (+)
• Length: 67 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
J5287_RS23155 (J5287_23135)	981141..982244	+	1104	WP_209185945.1	LLM class flavin-dependent oxidoreductase	-
J5287_RS23160 (J5287_23140)	982364..983545	+	1182	WP_209185944.1	acyl-CoA dehydrogenase family protein	-
J5287_RS23165 (J5287_23145)	983558..984529	+	972	WP_209185943.1	2-dehydropantoate 2-reductase N-terminal domain-containing protein	-
J5287_RS23170 (J5287_23150)	984534..985538	+	1005	WP_209185988.1	C-terminal binding protein	-
J5287_RS23175 (J5287_23155)	985669..985869	+	201	WP_142831764.1	type II toxin-antitoxin system VapB family antitoxin	Antitoxin
J5287_RS23180 (J5287_23160)	985866..986249	+	384	WP_209185942.1	type II toxin-antitoxin system VapC family toxin	Toxin
J5287_RS23185 (J5287_23165)	986519..987592	+	1074	WP_209185941.1	AAA family ATPase	-
J5287_RS23190 (J5287_23170)	987576..988319	+	744	WP_209185940.1	hypothetical protein	-
J5287_RS23195 (J5287_23175)	988864..989337	+	474	Protein_924	FCD domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (2-113)

Antitoxin

• Bacterial antitoxin of type II TA system, VapB (1-42)

Sequences

Toxin

Protein

• Length: 128 a.a.
• Molecular weight: 13994.23 Da
• Isoelectric Point: 9.0165

>T197407 WP_209185942.1 NZ_CP072147:985866-986249 [Rhizobium sp. K1/93]
VILVDTSIWIDHFRHGDVELRKVIADDRLLCHPVVVGELALGSLRDRGAVMAFFSAQREALVASHYEVITMIGRHSIFSM
GIGYTDAHLLASILLDRRSLLWTRDKRLAAAARKAGASLYAPTSAPN

Nucleotide

• Length: 384 bp

>T197407 NZ_CP096142:3085630-3085764 [Xanthomonas prunicola]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTCGGTATGCTGTCGGGCTGCAACACCGTCGCAGGTGC
TGGCAAGGACGTGAAGGGTGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin

Protein

• Length: 67 a.a.
• Molecular weight: 7125.13 Da
• Isoelectric Point: 10.4525

>AT197407 WP_142831764.1 NZ_CP072147:985669-985869 [Rhizobium sp. K1/93]
MRSTINLDDNLMEQARSLTGTKETAALVRQALETLVRVESGKRLAALGGTMPDAEAAPRRRSEAAK

Nucleotide

• Length: 201 bp

>AT197407 NZ_CP096142:3085403-3085555 [Xanthomonas prunicola]
ATGAAGCGACTGCTGACACTGATGGTACTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACATGCAGGGCGCAGGTGGGAAGGTCGAGAAAACCGCCGAAAAATGCAGCGACGGTAAGTGCTGA