197404

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) BrnTA/BrnT-BrnA
Location 3709262..3709814 Replicon chromosome
Accession NZ_CP072146
Organism Rhizobium sp. K1/93

Toxin (Protein)


Gene name brnT Uniprot ID -
Locus tag J5287_RS18095 Protein ID WP_209182916.1
Coordinates 3709554..3709814 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name brnA Uniprot ID -
Locus tag J5287_RS18090 Protein ID WP_209182915.1
Coordinates 3709262..3709570 (-) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J5287_RS18060 (J5287_18045) 3704924..3705553 + 630 WP_209182910.1 DNA-3-methyladenine glycosylase I -
J5287_RS18065 (J5287_18050) 3705646..3706116 + 471 WP_142824459.1 hypothetical protein -
J5287_RS18070 (J5287_18055) 3706130..3706840 - 711 WP_209182912.1 HAD family hydrolase -
J5287_RS18075 (J5287_18060) 3707074..3708123 + 1050 WP_142824094.1 aldo/keto reductase -
J5287_RS18080 (J5287_18065) 3708171..3708800 - 630 WP_209182913.1 phosphoribosyltransferase family protein -
J5287_RS18085 (J5287_18070) 3708850..3709212 - 363 WP_209182914.1 DUF305 domain-containing protein -
J5287_RS18090 (J5287_18075) 3709262..3709570 - 309 WP_209182915.1 BrnA antitoxin family protein Antitoxin
J5287_RS18095 (J5287_18080) 3709554..3709814 - 261 WP_209182916.1 BrnT family toxin Toxin
J5287_RS18100 (J5287_18085) 3709883..3710653 - 771 WP_209182917.1 hypothetical protein -
J5287_RS18105 (J5287_18090) 3710883..3712433 + 1551 WP_209182918.1 histidine--tRNA ligase -
J5287_RS18110 (J5287_18095) 3712465..3713586 + 1122 WP_209182919.1 ATP phosphoribosyltransferase regulatory subunit -
J5287_RS18115 (J5287_18100) 3713583..3714284 + 702 WP_209182920.1 ATP phosphoribosyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-77)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(27-100)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 9707.21 Da        Isoelectric Point: 10.3839

>T197404 WP_209182916.1 NZ_CP072146:c3709814-3709554 [Rhizobium sp. K1/93]
MKITWDERKRLANFDKHGLDFAELDADFFLAALLQPAKLGRFKAIGRRHDGTTAVIFAVLGREAVSVISMRPAHKAERSL
LNDKEN

Download         Length: 261 bp

>T197404 NZ_CP096141:316791-316943 [Xanthomonas prunicola]
ATGAAGCGACTGCTGACACTGATGGTACTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACATGCAGGGCGCAGGTGGGAAGGTCGAGAAAACCGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11769.13 Da        Isoelectric Point: 6.4167

>AT197404 WP_209182915.1 NZ_CP072146:c3709570-3709262 [Rhizobium sp. K1/93]
MTKKTEMRSDFQNGRGYSDQDWEEVSDNPEWTEEDFKNARPFAEVFPDLAESIRRARGRPAVEAPKRQISLRLDPDVIDA
FKATGKGWQSRINEALRKAAKI

Download         Length: 309 bp

>AT197404 NZ_CP096141:317018-317152 [Xanthomonas prunicola]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTCGGTATGCTGTCGGGCTGCAACACCGTCGCAGGTGC
TGGCAAGGACGTGAAGGGTGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References