Detailed information of TA system TA197403

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): pemIK/PRK09812-ChpS
• Location: 3537339..3537925
• Replicon: chromosome
• Accession: NZ_CP072146
• Organism: Rhizobium sp. K1/93

Toxin (Protein)

• Gene name: pemK
• Uniprot ID: -
• Locus tag: J5287_RS17265
• Protein ID: WP_209182789.1
• Coordinates: 3537596..3537925 (+)
• Length: 110 a.a.

Antitoxin (Protein)

• Gene name: pemI
• Uniprot ID: -
• Locus tag: J5287_RS17260
• Protein ID: WP_209182788.1
• Coordinates: 3537339..3537596 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
J5287_RS17255 (J5287_17240)	3535456..3537252	+	1797	WP_209187324.1	acyl-CoA dehydrogenase C-terminal domain-containing protein	-
J5287_RS17260 (J5287_17245)	3537339..3537596	+	258	WP_209182788.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	Antitoxin
J5287_RS17265 (J5287_17250)	3537596..3537925	+	330	WP_209182789.1	type II toxin-antitoxin system PemK/MazF family toxin	Toxin
J5287_RS17270 (J5287_17255)	3537973..3539181	+	1209	WP_209182790.1	acetyl-CoA C-acetyltransferase	-
J5287_RS17275 (J5287_17260)	3539274..3541487	+	2214	WP_209182791.1	FAD-dependent oxidoreductase	-
J5287_RS17280 (J5287_17265)	3541899..3542240	-	342	WP_209182792.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase PemK-like (1-109)

Antitoxin

• Antitoxin PemI-like (4-84)

Sequences

Toxin

Protein

• Length: 110 a.a.
• Molecular weight: 11877.67 Da
• Isoelectric Point: 9.8009

>T197403 WP_209182789.1 NZ_CP072146:3537596-3537925 [Rhizobium sp. K1/93]
VDRGDIWHVDLEPIRGREQAGARYVLVVTKKSFNAIGTPIVVPITTGGEFARFKGFAVSLSGAGTRSSGVIMCNQLRSLD
LRARGGKYVESVPDFIMSEVLARISTFFD

Nucleotide

• Length: 330 bp

>T197403 NZ_CP096140:3071738-3071872 [Xanthomonas prunicola]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTCGGTATGCTGTCGGGCTGCAACACCGTCGCAGGTGC
TGGCAAGGACGTGAAGGGTGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9295.58 Da
• Isoelectric Point: 4.3184

>AT197403 WP_209182788.1 NZ_CP072146:3537339-3537596 [Rhizobium sp. K1/93]
MATSTLRNVGGSVMMTIPKAVVDELGLTANTKVEVLAEDGRVVAVPHKRPKYTLDELLAQCDLDAPFTEEDRQWLDDAPS
GREVI

Nucleotide

• Length: 258 bp

>AT197403 NZ_CP096140:3071511-3071663 [Xanthomonas prunicola]
ATGAAGCGACTGCTGACACTGATGGTACTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACATGCAGGGCGCAGGTGGGAAGGTCGAGAAAACCGCCGAAAAATGCAGCGACGGTAAGTGCTGA