Detailed information of TA system TA197401

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PumAB/upstrm_HI1419-dnstrm_HI1420
• Location: 1519389..1519985
• Replicon: chromosome
• Accession: NZ_CP072146
• Organism: Rhizobium sp. K1/93

Toxin (Protein)

• Gene name: PumA
• Uniprot ID: -
• Locus tag: J5287_RS07560
• Protein ID: WP_209184289.1
• Coordinates: 1519692..1519985 (-)
• Length: 98 a.a.

Antitoxin (Protein)

• Gene name: PumB
• Uniprot ID: -
• Locus tag: J5287_RS07555
• Protein ID: WP_209184288.1
• Coordinates: 1519389..1519691 (-)
• Length: 101 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
J5287_RS31705	1516322..1516507	+	186	WP_247749157.1	BrnT family toxin	-
J5287_RS07535 (J5287_07530)	1516473..1516808	+	336	WP_209184285.1	BrnA antitoxin family protein	-
J5287_RS07540 (J5287_07535)	1517053..1517229	+	177	WP_209184286.1	hypothetical protein	-
J5287_RS07545 (J5287_07540)	1517405..1517857	-	453	WP_142823290.1	GatB/YqeY domain-containing protein	-
J5287_RS07550 (J5287_07545)	1518143..1519348	+	1206	WP_209184287.1	glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit	-
J5287_RS07555 (J5287_07550)	1519389..1519691	-	303	WP_209184288.1	putative addiction module antidote protein	Antitoxin
J5287_RS07560 (J5287_07555)	1519692..1519985	-	294	WP_209184289.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
J5287_RS07565 (J5287_07560)	1520068..1521474	-	1407	WP_209184290.1	MATE family efflux transporter	-
J5287_RS07570 (J5287_07565)	1521621..1522859	-	1239	WP_209184291.1	TCR/Tet family MFS transporter	-
J5287_RS07575 (J5287_07570)	1523030..1523941	-	912	WP_209184292.1	LysR family transcriptional regulator	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Addiction module killer protein, predicted (1-96)

Antitoxin

• Uncharacterized protein HI1420 (8-97)

Sequences

Toxin

Protein

• Length: 98 a.a.
• Molecular weight: 11236.07 Da
• Isoelectric Point: 10.8212

>T197401 WP_209184289.1 NZ_CP072146:c1519985-1519692 [Rhizobium sp. K1/93]
MPEVRQTILFRRWFDGLKDKRAVERITQRIVRLQAGLFGDIKFFDGIGELRVDHGPGYRVYFVQRGSVLVILLWGGDKSS
QTRDIRKAKAMANDLEI

Nucleotide

• Length: 294 bp

>T197401 NZ_CP096139:c2172564-2172412 [Xanthomonas prunicola]
ATGAAGCGACTGCTGACACTGATGGTACTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACATGCAGGGCGCAGGTGGGAAGGTCGAGAAAACCGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Antitoxin

Protein

• Length: 101 a.a.
• Molecular weight: 10352.89 Da
• Isoelectric Point: 7.0079

>AT197401 WP_209184288.1 NZ_CP072146:c1519691-1519389 [Rhizobium sp. K1/93]
MPVKTLPFDAADHLQSGQSQLELLSDAFNSGSASYVAVALGVIARAKGMTEVSKTAGITREALYKALSADGDPKLSTLLG
VLNALDLQLKLAPGNKKAPD

Nucleotide

• Length: 303 bp

>AT197401 NZ_CP096139:c2172337-2172203 [Xanthomonas prunicola]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTCGGTATGCTGTCGGGCTGCAACACCGTCGCAGGTGC
TGGCAAGGACGTGAAGGGTGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA