Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/HTH_26(antitoxin)
Location 140806..141420 Replicon chromosome
Accession NZ_CP072146
Organism Rhizobium sp. K1/93

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag J5287_RS00760 Protein ID WP_209183151.1
Coordinates 140806..141051 (+) Length 82 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag J5287_RS00765 Protein ID WP_209187356.1
Coordinates 141058..141420 (+) Length 121 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J5287_RS00740 (J5287_00735) 136848..137123 + 276 WP_209183147.1 YlcI/YnfO family protein -
J5287_RS00745 (J5287_00740) 137120..137419 + 300 WP_209183148.1 type II toxin-antitoxin system RelE/ParE family toxin -
J5287_RS00750 (J5287_00745) 137974..139032 + 1059 WP_209183149.1 LacI family DNA-binding transcriptional regulator -
J5287_RS00755 (J5287_00750) 139060..140712 - 1653 WP_209183150.1 choline dehydrogenase -
J5287_RS00760 (J5287_00755) 140806..141051 + 246 WP_209183151.1 cytotoxic translational repressor of toxin-antitoxin stability system Toxin
J5287_RS00765 (J5287_00760) 141058..141420 + 363 WP_209187356.1 helix-turn-helix transcriptional regulator Antitoxin
J5287_RS00770 (J5287_00765) 141432..142895 - 1464 WP_209183153.1 betaine-aldehyde dehydrogenase -
J5287_RS00775 (J5287_00770) 142897..144426 - 1530 WP_209183154.1 choline-sulfatase -
J5287_RS00780 (J5287_00775) 144423..145022 - 600 WP_209183155.1 transcriptional regulator BetI -
J5287_RS00785 (J5287_00780) 145192..145740 + 549 WP_209183156.1 HdeD family acid-resistance protein -
J5287_RS00790 (J5287_00785) 145942..146196 + 255 WP_209183157.1 type II toxin-antitoxin system ParD family antitoxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(67-114)


Sequences

Toxin        


Download         Length: 82 a.a.        Molecular weight: 9209.05 Da        Isoelectric Point: 10.9851

>T197400 WP_209183151.1 NZ_CP072146:140806-141051 [Rhizobium sp. K1/93]
MKDVVVSRLADKALMRMQPKRRLAIIEKVKAYARGEIVDIKKMKGGNLYRIRVGQDRVIIDDKGRIVVVIDAGPRGSIYK
E

Download         Length: 246 bp

>T197400 NZ_CP096139:c2172337-2172203 [Xanthomonas prunicola]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTCGGTATGCTGTCGGGCTGCAACACCGTCGCAGGTGC
TGGCAAGGACGTGAAGGGTGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 121 a.a.        Molecular weight: 13066.79 Da        Isoelectric Point: 4.3246

>AT197400 WP_209187356.1 NZ_CP072146:141058-141420 [Rhizobium sp. K1/93]
MGDIKRFEIDGKPYVLLSEEDYEDLVDGLRANAVLAGISAGEETWPLEIVEARANGGNAVRIFRNYRRMTVTELATAAGI
SQPYLSEIEAGKKTGSVDVLKRIANALKVDLDDLVVNVAD

Download         Length: 363 bp

>AT197400 NZ_CP096139:c2172564-2172412 [Xanthomonas prunicola]
ATGAAGCGACTGCTGACACTGATGGTACTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACATGCAGGGCGCAGGTGGGAAGGTCGAGAAAACCGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References