Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 901003..901667 Replicon chromosome
Accession NZ_CP072142
Organism Rhizobium sp. L51/94

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag J5274_RS22120 Protein ID WP_209186127.1
Coordinates 901239..901667 (+) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag J5274_RS22115 Protein ID WP_209186126.1
Coordinates 901003..901242 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J5274_RS28940 896230..896463 - 234 WP_257625690.1 hypothetical protein -
J5274_RS22090 (J5274_22100) 896497..897504 - 1008 WP_219275089.1 inositol 2-dehydrogenase -
J5274_RS22095 (J5274_22105) 897629..898642 + 1014 WP_219275091.1 LacI family DNA-binding transcriptional regulator -
J5274_RS22100 (J5274_22110) 899014..899259 + 246 WP_219275093.1 hypothetical protein -
J5274_RS22105 (J5274_22115) 899744..900034 + 291 WP_219275095.1 hypothetical protein -
J5274_RS22110 (J5274_22120) 900031..900747 + 717 WP_219275096.1 IS6 family transposase -
J5274_RS22115 (J5274_22125) 901003..901242 + 240 WP_209186126.1 Arc family DNA-binding protein Antitoxin
J5274_RS22120 (J5274_22130) 901239..901667 + 429 WP_209186127.1 type II toxin-antitoxin system VapC family toxin Toxin
J5274_RS22125 (J5274_22135) 901739..902029 + 291 WP_219275098.1 hypothetical protein -
J5274_RS22130 (J5274_22140) 902298..902993 - 696 WP_209207002.1 alpha/beta fold hydrolase -
J5274_RS22135 (J5274_22145) 903333..904007 - 675 WP_224128900.1 permease -
J5274_RS22140 (J5274_22150) 904387..904815 - 429 WP_219275099.1 hypothetical protein -
J5274_RS22145 (J5274_22155) 905038..905865 - 828 WP_209186131.1 aldo/keto reductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin

Arc-like DNA binding domain

(9-46)


Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15224.51 Da        Isoelectric Point: 5.8927

>T197394 WP_209186127.1 NZ_CP072142:901239-901667 [Rhizobium sp. L51/94]
MILLDTNVISEPLKSQPDPRVAAWIDTQAVETLYVAAISLAELRYGIAVHPDGKKKQAVQEKLDRLMLPLFRGRIMPFDE
AAAQAYAELRAAAAKKGKAIGDSDGYIAATAKANGLMIATRDTSPFEAAGLTVINPWEASNG

Download         Length: 429 bp

>T197394 NZ_CP096122:c51907-51587 [Acinetobacter portensis]
ATGTTATTTATAGAAACTAGCATTTTTACCAAGCAAATCAAAGATCTTGTAACTGATGAAGAATATCGTCAGCTTCAACA
AGATTTATTGGTTCAGCCTGATAAAGGTGACTTGATAAAAAATGGTGGTGGCATTCGTAAAGTGCGATGTGCCCAAGGAA
ATAAGGGGAAAAGTGGTGGTATCCGTGTGATCTATTATTGGGTTACAGAGGATGACCAGATCTTTTTTCTCATCGCTTAT
CCTAAATCAGTAAAAGACACATTGACTGATAAGGAGACAACGATTCTGCGTCAACTCGTGAAGGAGCAATTTCATGGATA
A

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8686.90 Da        Isoelectric Point: 7.2054

>AT197394 WP_209186126.1 NZ_CP072142:901003-901242 [Rhizobium sp. L51/94]
MASITIRNVPDEVHRALRVRAAQHGRSAEAEIRIILEQAAKPEGRVKLGSLLTQIGQEVGGFDLTIERDRTPSPPVSFE

Download         Length: 240 bp

>AT197394 NZ_CP096122:c51594-51322 [Acinetobacter portensis]
ATGGATAACAACCTATTTGATAGCCTCGTTTCTTCAATTAAAGAAGCAGGTTCAATTAAACGTAAAGAGATCCAAGCAAG
CCGAGTGATAGAGCTTGAACTACCCAATATTAAAGAAGTACGTGAAAAGACAGGGTTAAGCCAAGTCGAGTTTGCAGCAC
GTCTTCATATCAGTGCAAGAACGCTACAAAATTGGGAACAAGGTCGTCGCTATCCAACTGGGCCAGCAGCAACGCTTATC
CGTATCTTAGATGCACATCCAAGTGTGATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References