Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 2679723..2680327 Replicon chromosome
Accession NZ_CP072141
Organism Rhizobium sp. L51/94

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag J5274_RS13200 Protein ID WP_142822785.1
Coordinates 2679723..2680028 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag J5274_RS13205 Protein ID WP_142822787.1
Coordinates 2680025..2680327 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J5274_RS13180 (J5274_13175) 2675158..2675520 + 363 WP_142822779.1 glycine cleavage system protein GcvH -
J5274_RS13185 (J5274_13180) 2675520..2678384 + 2865 WP_142822781.1 aminomethyl-transferring glycine dehydrogenase -
J5274_RS13190 (J5274_13185) 2678421..2679044 - 624 WP_142822782.1 LysE family transporter -
J5274_RS13195 (J5274_13190) 2679140..2679532 - 393 WP_142822784.1 Fe-S cluster assembly scaffold SufA -
J5274_RS13200 (J5274_13195) 2679723..2680028 + 306 WP_142822785.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
J5274_RS13205 (J5274_13200) 2680025..2680327 + 303 WP_142822787.1 putative addiction module antidote protein Antitoxin
J5274_RS13210 (J5274_13205) 2680328..2680708 - 381 WP_142822788.1 SUF system Fe-S cluster assembly protein -
J5274_RS13215 (J5274_13210) 2680823..2682064 - 1242 WP_142822791.1 cysteine desulfurase -
J5274_RS13220 (J5274_13215) 2682077..2683351 - 1275 WP_142822793.1 Fe-S cluster assembly protein SufD -
J5274_RS13225 (J5274_13220) 2683374..2684129 - 756 WP_142822795.1 Fe-S cluster assembly ATPase SufC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(4-96)

Antitoxin

Uncharacterized protein HI1420

(4-91)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11896.78 Da        Isoelectric Point: 10.7321

>T197391 WP_142822785.1 NZ_CP072141:2679723-2680028 [Rhizobium sp. L51/94]
VFVIQRTEIFQQWIMRLKDRSAAARIASRILRAEDGNLRDVKPVGDGVEEMRIDYGPGYRIYFLRRRSVFVVLLVGGDKS
TQRRDIIEAKRLCAEWKERNQ

Download         Length: 306 bp

>T197391 NZ_CP096122:c19056-18700 [Acinetobacter portensis]
ATGTGGACAGTCATTACGACAGATCTATTTAATCAGTGGCTTGAACAGCAAGACGAATCAACACAAGAGAAGGTTCTGGC
TGCCCTGGTTGTTCTACAGCAGCAAGGACCAAGTTTAGGCCGCCCTTTAGTAGATACCGTCTATGACTCTAAATTTACCA
ACATGAAAGAGCTTCGTGTTCAACATCGAGGTAAACCACTGAGAGCTTTCTTCGCATTTGATCCATTACGTCAGGCCATT
GTGCTATGTATTGCTGATAAAGGCGGTAAAAAACGATTCTATACAGAGATGCTGGCAATTGCAGACCAACAATATGAACT
TCATCTCTCAACATTAGGAGAACAATCTAATGGCTAA

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10482.99 Da        Isoelectric Point: 5.0651

>AT197391 WP_142822787.1 NZ_CP072141:2680025-2680327 [Rhizobium sp. L51/94]
MTSDTRLFDASEVLDSESAIDEFLAAAFETEDPAFIAKSLGVIAKTRNMSAIARDVGMSRAALYKSLSGKGNPEFATIIK
VMKALGLGLAPVSRSNQGAA

Download         Length: 303 bp

>AT197391 NZ_CP096122:c18707-18405 [Acinetobacter portensis]
ATGGCTAAAACTTTGCAAGAATTATTAGCTAACCGCTCTCCAGAGAGCCAAGCCCGTATTCAAAAAATGGCAGATGAATT
ACTGCTAGAAAATCAGCTTCATCTTATTCGTGAAGAACTCGAAATTTCTCAAAAAGAGCTTGCTGAAACTTTGGGAATAA
AACAGCCATCGCTTTCAGCAATAGAAAATCGTGGCAATGATCTTAAGATTTCAACCATGAAAAAGTATGTTGAGGCAATG
GGCGGGAAGCTCCGTATTGATGTAGAGCTTCCAACAGGAAAACATATAGGATTCAATGTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References