Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 2193750..2194337 Replicon chromosome
Accession NZ_CP072141
Organism Rhizobium sp. L51/94

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag J5274_RS10775 Protein ID WP_142829519.1
Coordinates 2194047..2194337 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag J5274_RS10770 Protein ID WP_142829521.1
Coordinates 2193750..2194046 (-) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J5274_RS10750 (J5274_10745) 2189714..2190667 + 954 WP_224128276.1 murein L,D-transpeptidase catalytic domain family protein -
J5274_RS10755 (J5274_10750) 2190713..2191504 - 792 WP_142829526.1 sulfite exporter TauE/SafE family protein -
J5274_RS10760 (J5274_10755) 2191527..2192459 - 933 WP_142829524.1 N-acetyl-gamma-glutamyl-phosphate reductase -
J5274_RS10765 (J5274_10760) 2192542..2193495 - 954 WP_142829522.1 agmatinase -
J5274_RS10770 (J5274_10765) 2193750..2194046 - 297 WP_142829521.1 putative addiction module antidote protein Antitoxin
J5274_RS10775 (J5274_10770) 2194047..2194337 - 291 WP_142829519.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
J5274_RS10780 (J5274_10775) 2194462..2194932 - 471 WP_111220548.1 30S ribosomal protein S9 -
J5274_RS10785 (J5274_10780) 2194935..2195399 - 465 WP_111220549.1 50S ribosomal protein L13 -
J5274_RS10790 (J5274_10785) 2195993..2196319 - 327 WP_142829518.1 hypothetical protein -
J5274_RS10795 (J5274_10790) 2196429..2196860 + 432 WP_142829516.1 CoA-binding protein -
J5274_RS10800 (J5274_10795) 2196979..2198262 + 1284 WP_142829514.1 O-acetylhomoserine aminocarboxypropyltransferase -
J5274_RS10805 (J5274_10800) 2198389..2198733 + 345 WP_142829512.1 cupin domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-92)

Antitoxin

Uncharacterized protein HI1420

(5-91)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10727.40 Da        Isoelectric Point: 10.2980

>T197390 WP_142829519.1 NZ_CP072141:c2194337-2194047 [Rhizobium sp. L51/94]
VIEVRQTSIFANWLDALRDAQARQRIVVRIRRLELGNPGDIKPVGEGVSEMRIPHGPGYRLYFTRSGETIVILLCGGDKS
SQARDIAIARQLAKEI

Download         Length: 291 bp

>T197390 NZ_CP096122:c13835-13533 [Acinetobacter portensis]
ATGTACTCAATATATACCACTGAAGTCTTTGATGACTGGTTTACTAAGTTAAAAGACCAGCAGGCAAAAAGACGTATACA
AGTCCGAATTGATCGGGTTGAAGATGGAAACTTTGGAGATACTGAACCAGTAGGTGAAGGTGTTTCTGAATTACGTTTCT
TCTTTGGACCTGGCTACAGGATCTATTACTGTAAGCAAGGGCAAAGGGTCGTTATTCTTTTAGCAGGCGGAGACAAGTCT
ACGCAAAGTAAAGATATAAAACTTGCCCTACAATTAGCACAAGATTTAGAGGAGGAGCTGTAA

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10396.79 Da        Isoelectric Point: 4.4079

>AT197390 WP_142829521.1 NZ_CP072141:c2194046-2193750 [Rhizobium sp. L51/94]
MPLETTRFDIQDHLTTPADRMLYLEAAFEDGDPALITQALGDVARAAGMTSVAKEAGVTREALYKSLSEAGDPRLSTFLG
VIKALGLKVSISTDQNAA

Download         Length: 297 bp

>AT197390 NZ_CP096122:c13532-13251 [Acinetobacter portensis]
ATGGCTATCAAACTTCGTAAATGGGACAGTGCTGAACATCTTAAAACAGAAGAAGATATGCAAGCTTACCTACAAGCCTG
TATCGATGAATCTAATGGTGATGCGGCATTCATTGCAAAAGCTTTAGGTAATATTGCTAAAGCTAAAGGAATGGCTCAAT
TATCAAGAGACACTGGTTTAGGTCGAGAAAGTCTTTATAAAGCACTTTCTGGCGATGTAAATCCAAGCTTTGATACTGTT
ATTAAAGTCGTAAAAGCACTGAATTTACGCTTAGCAATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References