Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/HTH_26(antitoxin)
Location 1832145..1832759 Replicon chromosome
Accession NZ_CP072141
Organism Rhizobium sp. L51/94

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag J5274_RS08920 Protein ID WP_142824284.1
Coordinates 1832145..1832390 (+) Length 82 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag J5274_RS08925 Protein ID WP_142824285.1
Coordinates 1832397..1832759 (+) Length 121 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J5274_RS08900 (J5274_08895) 1828186..1828461 + 276 WP_219274926.1 YlcI/YnfO family protein -
J5274_RS08905 (J5274_08900) 1828458..1828757 + 300 WP_142824281.1 type II toxin-antitoxin system RelE/ParE family toxin -
J5274_RS08910 (J5274_08905) 1829313..1830371 + 1059 WP_142824282.1 LacI family DNA-binding transcriptional regulator -
J5274_RS08915 (J5274_08910) 1830399..1832051 - 1653 WP_142824283.1 choline dehydrogenase -
J5274_RS08920 (J5274_08915) 1832145..1832390 + 246 WP_142824284.1 cytotoxic translational repressor of toxin-antitoxin stability system Toxin
J5274_RS08925 (J5274_08920) 1832397..1832759 + 363 WP_142824285.1 helix-turn-helix transcriptional regulator Antitoxin
J5274_RS08930 (J5274_08925) 1832771..1834234 - 1464 WP_142824286.1 betaine-aldehyde dehydrogenase -
J5274_RS08935 (J5274_08930) 1834236..1835765 - 1530 WP_219274927.1 choline-sulfatase -
J5274_RS08940 (J5274_08935) 1835771..1836361 - 591 WP_142824288.1 transcriptional regulator BetI -
J5274_RS08945 (J5274_08940) 1836531..1837079 + 549 WP_142829209.1 HdeD family acid-resistance protein -
J5274_RS08950 (J5274_08945) 1837272..1837526 + 255 WP_142824290.1 type II toxin-antitoxin system ParD family antitoxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(67-114)


Sequences

Toxin        


Download         Length: 82 a.a.        Molecular weight: 9194.07 Da        Isoelectric Point: 10.9851

>T197389 WP_142824284.1 NZ_CP072141:1832145-1832390 [Rhizobium sp. L51/94]
MKDVVVSRLADKALMRMQPKRRLAIIEKVKAYARGEIVDIKKMKGGNLYRIRVGLDRVIIDDKGRIIVVIDAGPRGSIYK
D

Download         Length: 246 bp

>T197389 NZ_CP096122:c13532-13251 [Acinetobacter portensis]
ATGGCTATCAAACTTCGTAAATGGGACAGTGCTGAACATCTTAAAACAGAAGAAGATATGCAAGCTTACCTACAAGCCTG
TATCGATGAATCTAATGGTGATGCGGCATTCATTGCAAAAGCTTTAGGTAATATTGCTAAAGCTAAAGGAATGGCTCAAT
TATCAAGAGACACTGGTTTAGGTCGAGAAAGTCTTTATAAAGCACTTTCTGGCGATGTAAATCCAAGCTTTGATACTGTT
ATTAAAGTCGTAAAAGCACTGAATTTACGCTTAGCAATTTAA

Antitoxin


Download         Length: 121 a.a.        Molecular weight: 13084.87 Da        Isoelectric Point: 4.2616

>AT197389 WP_142824285.1 NZ_CP072141:1832397-1832759 [Rhizobium sp. L51/94]
MGDIKRFEIDGKPYVLLSEEDYEDLVDGLRANAVLAGISAGEETWPLEIVEARANGGNAVRIFRNYRRMTVTELAMAAGI
SQPYLSEIEAGKKTGSVDVLKRIATALKVDLDDLVVDVAD

Download         Length: 363 bp

>AT197389 NZ_CP096122:c13835-13533 [Acinetobacter portensis]
ATGTACTCAATATATACCACTGAAGTCTTTGATGACTGGTTTACTAAGTTAAAAGACCAGCAGGCAAAAAGACGTATACA
AGTCCGAATTGATCGGGTTGAAGATGGAAACTTTGGAGATACTGAACCAGTAGGTGAAGGTGTTTCTGAATTACGTTTCT
TCTTTGGACCTGGCTACAGGATCTATTACTGTAAGCAAGGGCAAAGGGTCGTTATTCTTTTAGCAGGCGGAGACAAGTCT
ACGCAAAGTAAAGATATAAAACTTGCCCTACAATTAGCACAAGATTTAGAGGAGGAGCTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References