197388

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 1765954..1766434 Replicon chromosome
Accession NZ_CP072141
Organism Rhizobium sp. L51/94

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag J5274_RS08605 Protein ID WP_142824235.1
Coordinates 1766162..1766434 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag J5274_RS08600 Protein ID WP_142824234.1
Coordinates 1765954..1766178 (+) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J5274_RS08565 (J5274_08560) 1761174..1761521 - 348 WP_142824228.1 DUF86 domain-containing protein -
J5274_RS08570 (J5274_08565) 1761522..1761818 - 297 WP_142824229.1 nucleotidyltransferase domain-containing protein -
J5274_RS08575 (J5274_08570) 1761963..1763096 + 1134 WP_142824230.1 site-specific DNA-methyltransferase -
J5274_RS08580 (J5274_08575) 1763211..1763576 - 366 WP_142824231.1 nuclear transport factor 2 family protein -
J5274_RS08585 (J5274_08580) 1763581..1764195 - 615 WP_142824232.1 HAD family phosphatase -
J5274_RS08590 (J5274_08585) 1764212..1765291 - 1080 WP_142824471.1 A/G-specific adenine glycosylase -
J5274_RS08595 (J5274_08590) 1765391..1765891 + 501 WP_142824233.1 DUF721 domain-containing protein -
J5274_RS08600 (J5274_08595) 1765954..1766178 + 225 WP_142824234.1 DUF6290 family protein Antitoxin
J5274_RS08605 (J5274_08600) 1766162..1766434 + 273 WP_142824235.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
J5274_RS08610 (J5274_08605) 1766646..1767341 + 696 WP_142824236.1 DsbA family protein -
J5274_RS08615 (J5274_08610) 1767738..1771196 + 3459 WP_142824237.1 chromosome segregation SMC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-88)

Antitoxin

Relaxosome protein TraY

(4-49)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10728.29 Da        Isoelectric Point: 10.3301

>T197388 WP_142824235.1 NZ_CP072141:1766162-1766434 [Rhizobium sp. L51/94]
MAWRIEFQRSAERDLEKLDHESVKRILRFLHTRVASLEDPRSIGEALRGSELGNFWKYRVGDYRIIVDIDDGTVRILVVR
IGNRKDVYRR

Download         Length: 273 bp

>T197388 NZ_CP096121:c89868-89575 [Acinetobacter portensis]
ATGACTTATAAGCTTTTACGTCACAAGGACTTTACAGCAGAATGGGAAAAACTCCCTGTTGCTATACGAGATCAATTTAA
AAAGAAACTAGCCAAAGTCATAGAGCAGCCACATATTCCAAAGAATATGCTTAGAGGCGATCTTGCAGGTTGCTATAAAA
TCAAATTATTAAAAGCTGGTGTCCGACTTGTCTATCAAGTTAAAGATGATCAGGTAGTTATCCTGCTCATTACCGTCGGA
AAACGAGCTGATAGCATAGTTTATGACGAAGCGAAAAAGCGAATTAAAGACTAA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8556.63 Da        Isoelectric Point: 4.5468

>AT197388 WP_142824234.1 NZ_CP072141:1765954-1766178 [Rhizobium sp. L51/94]
MLALRLPPEIEARLDELAKRTGRSKSFYARQAILEHLDDLEDLYVAEQRLEEFRRGDSDSISLAELMARHGVED

Download         Length: 225 bp

>AT197388 NZ_CP096121:c90103-89858 [Acinetobacter portensis]
ATGGCTACTGTTAACTTCAGGATCGATGAAGCCCTTAAAGAAAAATCTTATTCAATCCTTAAAGAGCAAGGTATTGCACC
TACTGATTTCTTCACTAGTATTCTTGAGTATGTTGCTACGACTGGGAAACTGCCTGTCAAAAAAGCTTTGCTTTCGGAAG
AAGATGAAGAATTATTAGCTCTTGTCCGTAAGCGCATTAATGATCCTAAAGAGATGTTTGAGGAAGTCACATTAGATGAC
TTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References