Detailed information of TA system TA197387

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): pemIK/PRK09812-ChpS
• Location: 1427191..1427777
• Replicon: chromosome
• Accession: NZ_CP072141
• Organism: Rhizobium sp. L51/94

Toxin (Protein)

• Gene name: pemK
• Uniprot ID: -
• Locus tag: J5274_RS06970
• Protein ID: WP_142823967.1
• Coordinates: 1427448..1427777 (+)
• Length: 110 a.a.

Antitoxin (Protein)

• Gene name: pemI
• Uniprot ID: -
• Locus tag: J5274_RS06965
• Protein ID: WP_142823966.1
• Coordinates: 1427191..1427448 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
J5274_RS06960 (J5274_06955)	1425308..1427104	+	1797	WP_142829129.1	acyl-CoA dehydrogenase C-terminal domain-containing protein	-
J5274_RS06965 (J5274_06960)	1427191..1427448	+	258	WP_142823966.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	Antitoxin
J5274_RS06970 (J5274_06965)	1427448..1427777	+	330	WP_142823967.1	type II toxin-antitoxin system PemK/MazF family toxin	Toxin
J5274_RS06975 (J5274_06970)	1427824..1429032	+	1209	WP_142823968.1	acetyl-CoA C-acetyltransferase	-
J5274_RS06980 (J5274_06975)	1429123..1431336	+	2214	WP_219274893.1	3-hydroxyacyl-CoA dehydrogenase NAD-binding domain-containing protein	-
J5274_RS06985 (J5274_06980)	1431748..1432089	-	342	WP_142823970.1	oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase PemK-like (3-108)

Antitoxin

• Antitoxin PemI-like (4-84)

Sequences

Toxin

Protein

• Length: 110 a.a.
• Molecular weight: 11945.81 Da
• Isoelectric Point: 9.8009

>T197387 WP_142823967.1 NZ_CP072141:1427448-1427777 [Rhizobium sp. L51/94]
VDRGDIWHVDLEPIRGREQAGARYVLVVTKKSFNAIGTPIVVPITTGGEFARFKGFAVSLSGAGTRSSGVILCNQLRSLD
LRARGGKYVESVPDFIMFEVLARITIFFD

Nucleotide

• Length: 330 bp

>T197387 NZ_CP096121:c78700-78398 [Acinetobacter portensis]
ATGTACTCAATATATACCACTGAAGTCTTTGATGACTGGTTCACCAAGTTAAAAGACCAGCAGGCAAAAAGACGCATACA
AGTCCGAATTGATCGGGTTGAAGATGGAAACTTTGGAGATACTGAGCCGGTCGGTGAAGGTGTTTCTGAATTACGTTTCT
TCTTTGGGCCAGGCTATAGGATTTATTACTGCAAGCAAGGGCAAAGGGTTGTTATTCTTTTAGCAGGCGGAGATAAGTCT
ACGCAAAGTAAAGATATAAAACTTGCCCTGCAATTGGCACAAGATTTAGAGGAGGAGCTATAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9296.57 Da
• Isoelectric Point: 4.2457

>AT197387 WP_142823966.1 NZ_CP072141:1427191-1427448 [Rhizobium sp. L51/94]
MATSTLRNVGGSVMMTIPKAVVDELGLTANTKVEVLAEDGRVVAVPHKRPKYTLDELLAQCDLDAPFTEEDREWLDDAPS
GREVI

Nucleotide

• Length: 258 bp

>AT197387 NZ_CP096121:c78397-78116 [Acinetobacter portensis]
ATGGCTATTAAACTTCGCAAATGGGACAGTGCTGAGCATCTTAAAACAGAGGATGATATGCAGGCTTACTTACAAGCATG
TATTGAAGAATCTAATGGCGATGCCGCATTCATTGCAAAGGCTTTAGGTAACATTGCAAAAGCTAAAGGAATGGCTCAAT
TATCACGAGATACAGGCTTAGGCCGAGAAAGTCTTTATAAAGCACTTTCTGGTGATGTTAACCCTAGTTTTGATACTGTG
ATTAAAGTTGTAAAAGCACTGAATTTACGCTTAGCAATTTAA