Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 43625..44223 Replicon plasmid unnamed1
Accession NZ_CP072139
Organism Agrobacterium sp. S7/73

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag J5276_RS29530 Protein ID WP_209159983.1
Coordinates 43930..44223 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag J5276_RS29525 Protein ID WP_209159982.1
Coordinates 43625..43933 (+) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J5276_RS29510 (J5276_29525) 39830..42190 - 2361 WP_209159979.1 hypothetical protein -
J5276_RS29515 (J5276_29530) 42340..42918 - 579 WP_209159980.1 PIN domain-containing protein -
J5276_RS29520 (J5276_29535) 42908..43354 - 447 WP_209159981.1 DNA-binding protein -
J5276_RS29525 (J5276_29540) 43625..43933 + 309 WP_209159982.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
J5276_RS29530 (J5276_29545) 43930..44223 + 294 WP_209159983.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
J5276_RS30700 44284..44541 - 258 WP_255610431.1 SIP domain-containing protein -
J5276_RS30705 44787..44849 - 63 Protein_52 hypothetical protein -
J5276_RS29540 (J5276_29555) 44876..45529 + 654 WP_229002292.1 ABC transporter permease -
J5276_RS29545 (J5276_29560) 45574..46041 + 468 Protein_54 class I SAM-dependent methyltransferase -
J5276_RS29550 (J5276_29565) 46930..47934 + 1005 WP_209159984.1 alpha/beta hydrolase -
J5276_RS29555 (J5276_29570) 47918..48331 + 414 WP_209159985.1 DoxX family protein -
J5276_RS29560 (J5276_29575) 48353..48492 + 140 Protein_57 fasciclin domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..184677 184677


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-52)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10568.08 Da        Isoelectric Point: 5.7904

>T197385 WP_209159983.1 NZ_CP072139:43930-44223 [Agrobacterium sp. S7/73]
VKLTWSAFALSDRDAIFTYIEADNPAAAVLVDERIVAASRRLLDFPASGRVGRIAGTRELVINGTPYVAVYAVTDTTVRI
LRVLHGAQEWPESVPIS

Download         Length: 294 bp

>T197385 NZ_CP096121:c75990-75670 [Acinetobacter portensis]
ATGTTATTTATTGAAACCAGCATCTTTACCAAGCAAATTAAAGACCTTGTATCTGATGAGGAATATCGTCAACTTCAGCA
AGATCTTTTGGTACAGCCTGATAGAGGTGACCTAATCAAGAATGGCGGTGGTATTCGCAAAGTACGTTGTGCTCAAGGTA
ACAAAGGGAAAAGTGGTGGGATACGGGTGATTTATTATTGGGTCACCGAGGATGATCAGATCTTTTTCTTAGTGGCTTAT
CCAAAATCAGTAAAAGATAATTTAACAGATAAGGAAACCGCCATTCTGCACCAACTCGTGAAGGAGCAATTTCATGGATA
A

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11055.46 Da        Isoelectric Point: 4.8892

>AT197385 WP_209159982.1 NZ_CP072139:43625-43933 [Agrobacterium sp. S7/73]
MAANALVQTRIDAEVRDRASAVLESMGLTVSDAVRILLTRTANEGALPLELLSGSEAHDVWFRNKVLEALNDTRPDVSDD
EVEAHFAERRAAARLKAGALKS

Download         Length: 309 bp

>AT197385 NZ_CP096121:c75677-75405 [Acinetobacter portensis]
ATGGATAACAACTTATTTGATGACTTGGTTGCTTCAATCAAAGAAGCTGGAGCTATCAAACGTAAAGAAGTTAAAGCAAG
CCGAGTTACAGAACTCGAATTGCCTGATATTAAAGAAGTACGTGAAAAAACTGGCTTGAGCCAAAATGAATTTGCTGCAC
GTCTACATATTAGCCCCCGTACCCTGCAAAATTGGGAACAGGGACGACGCTATCCAACTGGACCAGCAGCTACATTGATT
CGAATTTTAGATGCTCACCCAAGCCTTATTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References