Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 144739..145505 Replicon plasmid pTiS7_73
Accession NZ_CP072138
Organism Agrobacterium sp. S7/73

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag J5276_RS25160 Protein ID WP_209159800.1
Coordinates 144739..145221 (-) Length 161 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag J5276_RS25165 Protein ID WP_209159801.1
Coordinates 145221..145505 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J5276_RS25125 (J5276_25140) 140134..140760 + 627 WP_209159793.1 thermonuclease family protein -
J5276_RS25130 (J5276_25145) 140757..141389 + 633 WP_209159794.1 thermonuclease family protein -
J5276_RS25135 (J5276_25150) 141390..141704 + 315 WP_209159795.1 hypothetical protein -
J5276_RS25140 (J5276_25155) 141713..142084 + 372 WP_209159796.1 hypothetical protein -
J5276_RS25145 (J5276_25160) 142115..142648 + 534 WP_229002329.1 hypothetical protein -
J5276_RS25150 (J5276_25165) 142683..143021 - 339 WP_209159798.1 helix-turn-helix domain-containing protein -
J5276_RS25155 (J5276_25170) 143331..144677 + 1347 WP_209159799.1 hypothetical protein -
J5276_RS25160 (J5276_25175) 144739..145221 - 483 WP_209159800.1 GNAT family N-acetyltransferase Toxin
J5276_RS25165 (J5276_25180) 145221..145505 - 285 WP_209159801.1 DUF1778 domain-containing protein Antitoxin
J5276_RS25170 (J5276_25185) 145747..146091 - 345 WP_209159802.1 hypothetical protein -
J5276_RS25175 (J5276_25190) 146186..148972 - 2787 WP_209159803.1 type IV secretory system conjugative DNA transfer family protein -
J5276_RS25180 (J5276_25195) 148941..149990 - 1050 WP_209159804.1 P-type DNA transfer ATPase VirB11 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - htpB 1..1007991 1007991


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(41-141)

Antitoxin

Vibrio phage ICP1, Orf50

(15-86)


Sequences

Toxin        


Download         Length: 161 a.a.        Molecular weight: 17320.86 Da        Isoelectric Point: 7.2427

>T197381 WP_209159800.1 NZ_CP072138:c145221-144739 [Agrobacterium sp. S7/73]
MLSAPALLEEAHDLDLFQSGNDTLDEWLRRRARPNQVSGASRTYVVAEGQRVVGYYCLASGALDLADAPGSVRRNMPDPI
PMAVLGRLAIDRGWQGRGLGAALLQDAVLRTSQAASIMGIRGLLVHAISEDAKAFYEHYGFLCSPNQPMTLVLSLKIRTG

Download         Length: 483 bp

>T197381 NZ_CP096119:202821-204146 [Salmonella enterica subsp. enterica serovar Indiana]
ATGAGCCGGAAACAGCAACGTCTGGTAATTTGGATGAACGGCATCAAAGTCGGGTACTGGGAAAAAAGCAAAGGGGTAGA
CAGCTTAGAATACCTTCCTGAATGGGTTGCTGACGAACAGGGAAGGCCGCTGTCATTGTCCCTTCCTTTTACTCCCGGGA
ACCAGGTCTGGCGTGGAAATGTGGTACGTGACTATTTTGATAATTTACTGCCGGACAGCGAAGGCATACGCAGACGTCTG
GCAATGCGTTACAAGGCCGATAGCCTGGAGCCTTTTGATCTGCTGACGGAGCTGGGAAAAGACTGCGTGGGCGCGATACA
GCTGCTTCATGACGGAGATGAACCCACTGATTTATATTCCGTGAAGTATCACCCGCTTACTGAATCAGAAATTGCGGCAA
CTTTGCGTAATACCACGGAGACATTGCTACCGGGCAGGCCAGAAGATAACGACGACTTACGTTTATCTATTGCCGGTGCT
CAGGAGAAAACAGCCCTACTGTGGCATGAAGATCGGTGGTGTATGCCGGAGGGTAATACACCAACGACGCATATATTCAA
GCTACCGCTCGGACTTGTGGGGAACATGAAAGCCGACATGAGCTCGTCGGTTGAAAATGAATGGCTCTGCTCGGTACTTC
TCGGCCAGTACGGGCTCCCCGTGGCAAGAACGCAGATTGCTCACTTTGAAGATCAGAAAGCGCTGGTGGTAGAACGTTTT
GACCGAAAATGGTCAGGAGACGGACAATGGATCATTCGTTTACCCCAGGAGGATATGTGTCAGGCCCTGGGCGTTTCGCC
ATTACGAAAATATCAGGCGGACGGCGGGCCAGGTATATCGGAAATTATGGAGGTTCTGAGTAATTCAGACCGTGCTGAGC
GTGACAAAGCGCAGTTTTTTATGACGCAGATAATTTTCTGGATGATGGCCGCAACAGATGGCCACGCTAAAAATTTCAGT
ATTTCTATTGGGCCACAGGGACGTTATCACCTTACACCAAACTATGATGTGTTGTCGGCATGGCCGGTGATCGGTCATGG
GAACAATCAGATATCCTGGCAGAAGTGCAAACTGGCGATGGCCGTACGTGGCAGTAGCAACTATTACCAGATATATCGAA
TACAACGACGCCACTGGATCAGGCATGGTGAGATAACCGGCCTGAGTAAACAGCAGACAGAGGCGATGATAGAGGAAATC
ATCGCCAGAACCCCGGGTGTCATTGAACGTGTTAGCGGGCTTCTTCCGGACCAGTTCCCCCAGCAGCTTGCGGAAAGTAT
TTTTGATGGAATGAGGCAGCAATGCAGGCGCCTGGCTGAGAAATGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10723.12 Da        Isoelectric Point: 7.3189

>AT197381 WP_209159801.1 NZ_CP072138:c145505-145221 [Agrobacterium sp. S7/73]
MATKSLTDSHAKPVHLRIREDVRKVIDRAASIRGKSRTDFMIDAAYRAAEDALLDQTLVRVDEDSYRHFLSVLDQPPNGE
GFERLMNAPKPWQS

Download         Length: 285 bp

>AT197381 NZ_CP096119:202523-202816 [Salmonella enterica subsp. enterica serovar Indiana]
ATCAATAATGATTACCCGTTAAACACGCTCAACCAGCTGCGTCCCTTGCTCATTGGTTTTCGCAAGGCGAATGGCCTGAC
GCAAAAAGACCTGTCCGAAAGGTTAGGCGTCACTCAACAGACATACTCACGTCTGGAAGCCAACCCTGCCAGTGCGAGCA
TTGAACGGCTATTCAAGGTGTTTTCCATCCTGGGCGTAAAAATCAGCTTCTCCTCGGCAACCACCTCTTCAGAGAGGAAG
CAGACGGAAGAAATGCTTAAATCAAACTCACCTGCACGACAGGAGGATTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References