Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2390168..2390336 Replicon chromosome
Accession NZ_CP072119
Organism Klebsiella michiganensis strain 12084

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2390226..2390329 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2390168..2390336 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J5O09_RS11485 (J5O09_11485) 2385295..2387355 + 2061 WP_014229840.1 oligopeptidase B -
J5O09_RS11490 (J5O09_11490) 2387362..2388021 - 660 WP_014229839.1 exodeoxyribonuclease X -
J5O09_RS11495 (J5O09_11495) 2388100..2388330 - 231 WP_004103351.1 DNA polymerase III subunit theta -
J5O09_RS11500 (J5O09_11500) 2388466..2388840 + 375 WP_014229838.1 CopC domain-containing protein YobA -
J5O09_RS11505 (J5O09_11505) 2388845..2389714 + 870 WP_038424672.1 copper homeostasis membrane protein CopD -
J5O09_RS11510 (J5O09_11510) 2389731..2390069 + 339 WP_004103344.1 YebY family protein -
- 2390168..2390336 - 169 - - Antitoxin
- 2390226..2390329 + 104 - - Toxin
J5O09_RS11515 (J5O09_11515) 2390454..2391413 - 960 WP_025106131.1 spore coat protein U domain-containing protein -
J5O09_RS11520 (J5O09_11520) 2391428..2393758 - 2331 WP_076752314.1 fimbria/pilus outer membrane usher protein -
J5O09_RS11525 (J5O09_11525) 2393761..2394525 - 765 WP_042945473.1 fimbria/pilus periplasmic chaperone -
J5O09_RS11530 (J5O09_11530) 2394544..2395062 - 519 WP_004852079.1 spore coat U domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T197342 NZ_CP072119:2390226-2390329 [Klebsiella michiganensis]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 169 bp

>AT197342 NZ_CP072119:c2390336-2390168 [Klebsiella michiganensis]
AACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTTACCGTGTCAGGTTTTCCAGTCCGCGACAAAAGTG
GACGAATAA

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References