Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 3087897..3088576 Replicon chromosome
Accession NZ_CP072113
Organism Yimella sp. cx-51

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag J5M86_RS14690 Protein ID WP_188061289.1
Coordinates 3087897..3088325 (-) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag J5M86_RS14695 Protein ID WP_188061290.1
Coordinates 3088322..3088576 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J5M86_RS14665 (J5M86_14665) 3083824..3084330 - 507 WP_188061285.1 DUF6328 family protein -
J5M86_RS14670 (J5M86_14670) 3084556..3085155 + 600 WP_188061286.1 nicotinamide riboside transporter PnuC -
J5M86_RS14675 (J5M86_14675) 3085152..3086168 + 1017 WP_188061287.1 AAA family ATPase -
J5M86_RS14680 (J5M86_14680) 3086170..3087108 - 939 WP_244328380.1 amidohydrolase family protein -
J5M86_RS14685 (J5M86_14685) 3087279..3087830 - 552 WP_188061288.1 hypothetical protein -
J5M86_RS14690 (J5M86_14690) 3087897..3088325 - 429 WP_188061289.1 type II toxin-antitoxin system VapC family toxin Toxin
J5M86_RS14695 (J5M86_14695) 3088322..3088576 - 255 WP_188061290.1 antitoxin Antitoxin
J5M86_RS14700 (J5M86_14700) 3088634..3089839 - 1206 WP_188061291.1 ATP-binding protein -
J5M86_RS14705 (J5M86_14705) 3089885..3090637 - 753 WP_188061292.1 VC0807 family protein -
J5M86_RS14710 (J5M86_14710) 3090891..3091958 + 1068 WP_188061293.1 GNAT family N-acetyltransferase -
J5M86_RS14715 (J5M86_14715) 3092036..3092581 - 546 WP_188061294.1 DUF1697 domain-containing protein -
J5M86_RS14720 (J5M86_14720) 3092653..3093501 - 849 WP_188061295.1 pyridoxal kinase PdxY -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain toxin

(1-134)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15078.31 Da        Isoelectric Point: 5.0722

>T197302 WP_188061289.1 NZ_CP072113:c3088325-3087897 [Yimella sp. cx-51]
MKIVDTNVLLYAVNAGSAPHSACRAWLIDALEGAEGVGLPWVSLLGFIRISTNPRIFEHPLTSAQATDLVQAWLAQPSAL
TPEPTPRHASILAGLVAPSGVAGNLTTDAHLAALALEYDAEVVTMDRDFERFGVRVVVPGRL

Download         Length: 429 bp

>T197302 NZ_CP095923:c157586-157305 [Pseudomonas aeruginosa]
ATGAGCCTGAAGTGGACCCGCAAGGCGGCCGCCGACCTGGACGCCATCTACGACCATTACGTCGTGCTGATCGGCCCGGA
AAAAGCCCTGAAAGCCGTCCAGGACATCGTCGAGCAGGTGAAACCGCTGCAGCAGGTAGCCAACCAGGGGGCAGGGCGGC
CCAGCGAGGTGCCAGGCGTACGCACCCTGACCCTGGAGCGCTGGCCGTTCAGCGCCCCTTTTCGGGTAAAAGGCAAGGAA
ATCCAGATTTTGCGCATCGACAGGGTCGAAATTACCCCATAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9263.61 Da        Isoelectric Point: 4.8228

>AT197302 WP_188061290.1 NZ_CP072113:c3088576-3088322 [Yimella sp. cx-51]
MARTTVTLESDVEAMIARLMAERGISFKEALNQAVRRGLSSGVRADFVMPSFDMGSPLVDLTHASRIAGELEDEEIVREL
RVGR

Download         Length: 255 bp

>AT197302 NZ_CP095923:c157810-157583 [Pseudomonas aeruginosa]
ATGAGCACCGTAGTCTCGTTCCGCGCCGATGACGCCCTGGTCGCGGCCCTCGACGAACTGGCCCGCGCCACCCACCGCGA
CCGCCCGTATCACCTGCGGCAGGCGCTCGCGCAGTACCTGGAAAGGCAGCAGTGGCAGGTCGCTGCCATCGATGAAGGCT
TGGCCGATGCCAATGCCGGTCGCCTGCTGGAACACACCGAGATCGAGAAGCGCTGGGGGCTGCAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References