Detailed information of TA system TA197301

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/PIN(toxin)
• Location: 173624..174308
• Replicon: chromosome
• Accession: NZ_CP072113
• Organism: Yimella sp. cx-51

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: J5M86_RS00815
• Protein ID: WP_208965069.1
• Coordinates: 173624..174037 (-)
• Length: 138 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: J5M86_RS00820
• Protein ID: WP_188060008.1
• Coordinates: 174054..174308 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
J5M86_RS00810 (J5M86_00810)	171841..173577	+	1737	WP_188060010.1	arginine--tRNA ligase	-
J5M86_RS00815 (J5M86_00815)	173624..174037	-	414	WP_208965069.1	PIN domain-containing protein	Toxin
J5M86_RS00820 (J5M86_00820)	174054..174308	-	255	WP_188060008.1	type II toxin-antitoxin system VapB family antitoxin	Antitoxin
J5M86_RS00825 (J5M86_00825)	174523..176331	-	1809	WP_188060007.1	alpha/beta fold hydrolase	-
J5M86_RS00830 (J5M86_00830)	176437..176604	-	168	WP_188060006.1	type II toxin-antitoxin system VapC family toxin	-
J5M86_RS00835 (J5M86_00835)	176725..177747	-	1023	WP_188060005.1	UDP-glucose 4-epimerase GalE	-
J5M86_RS00840 (J5M86_00840)	177771..178343	+	573	WP_188060004.1	DivIVA domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (2-128)

Antitoxin

• Bacterial antitoxin of type II TA system, VapB (1-35)

Sequences

Toxin

Protein

• Length: 138 a.a.
• Molecular weight: 15246.45 Da
• Isoelectric Point: 6.4897

>T197301 WP_208965069.1 NZ_CP072113:c174037-173624 [Yimella sp. cx-51]
VNVVLAMHRQDHPQHSPVRAWFDQVVENGEDFGVPLTVWGSFLRITTNRRVFKVPTPLHDAFTFIDALRGQPGHIQLEPG
IRHLVLLQRIAERSDAYGDLVPDVVLAAIAAEAGAKVASLDRDFARIADIEVVRPVQ

Nucleotide

• Length: 414 bp

>T197301 NZ_CP095922:c5331947-5331669 [Pseudomonas aeruginosa]
ATGATTCTGACCTTTCGCTGCGACGAGACTCGTCAGCTTTTTGAGACGGGTCTTTCGAGGCGGTGGGGAGCGATCCTCAC
AGTCGCTACGCGTAAGCTCGCAATGCTTCATGCGGCTAGGGAGCTTCGAGACCTGCGCTCTCCACCTGGAAACCGGTTGG
AGCCGTTGCAGGGAAAGCGGGCGGGCCAACATAGCATCAGGATCAATGACCAGTGGCGTGTCTGTTTCGTCTGGACGGAT
GCGGGTCCCGAAGAAGTCGAAATAGTTGATTACCACTGA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9376.67 Da
• Isoelectric Point: 5.8634

>AT197301 WP_188060008.1 NZ_CP072113:c174308-174054 [Yimella sp. cx-51]
MRTTLSIDDELLARARERARERGITLGAVVENALRRDFASEVRTDAPPLPVFTKGSGPKPGIDLTSNRVLHEVLDEDLPL
DRLR

Nucleotide

• Length: 255 bp

>AT197301 NZ_CP095922:c5331657-5331352 [Pseudomonas aeruginosa]
ATGGCTACCAATGGTATGCGCCCCATCCATCCTGGGGAAATATTGCGCGATGAGTTTCTGATGGAGTTTGATATCTCTCC
AGCTGCTCTAGCACGCGCTTTGAAAGTCTCCGCTCCGACAGTGAACGATATCGTTCGTGAGCAGCGTGGTATCTCCGCAG
ATATGGCGATTCGTCTGGGGCGTTACTTTGATACGTCCGCTCAGTTCTGGATGAATCTCCAGAGTGAGTATTCGTTAGCA
ACTGCTTATGCGGCGAATGGCAAGCAGATCGAACATGAGATTGAGCCGCTGCTTGCTCACGGATAG