Detailed information of TA system TA197300

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-yefM/YoeB-YefM
• Location: 937232..937746
• Replicon: chromosome
• Accession: NZ_CP072111
• Organism: Corynebacterium hindlerae strain 1864

Toxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: J5O04_RS04435
• Protein ID: WP_208768809.1
• Coordinates: 937492..937746 (+)
• Length: 85 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: J5O04_RS04430
• Protein ID: WP_208768808.1
• Coordinates: 937232..937486 (+)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
J5O04_RS04410 (J5O04_04410)	932736..933869	-	1134	WP_208768804.1	histidine kinase	-
J5O04_RS04415 (J5O04_04415)	933880..934707	-	828	WP_208768805.1	hypothetical protein	-
J5O04_RS04420 (J5O04_04420)	934710..935369	-	660	WP_208768806.1	ABC transporter ATP-binding protein	-
J5O04_RS04425 (J5O04_04425)	935491..937083	+	1593	WP_208768807.1	hypothetical protein	-
J5O04_RS04430 (J5O04_04430)	937232..937486	+	255	WP_208768808.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
J5O04_RS04435 (J5O04_04435)	937492..937746	+	255	WP_208768809.1	Txe/YoeB family addiction module toxin	Toxin
J5O04_RS04440 (J5O04_04440)	938018..939151	-	1134	WP_208768810.1	hydrogenase formation protein HypD	-
J5O04_RS04445 (J5O04_04445)	939148..939411	-	264	WP_208768811.1	HypC/HybG/HupF family hydrogenase formation chaperone	-
J5O04_RS04450 (J5O04_04450)	939486..940589	+	1104	WP_208768812.1	hydrogenase expression/formation protein HypE	-
J5O04_RS04455 (J5O04_04455)	940688..940990	+	303	WP_208768813.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (1-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-74)

Sequences

Toxin

Protein

• Length: 85 a.a.
• Molecular weight: 10195.62 Da
• Isoelectric Point: 7.3569

>T197300 WP_208768809.1 NZ_CP072111:937492-937746 [Corynebacterium hindlerae]
MLLTWDENAWEDYLWWQAHDRKVLKRINALIKDIARNGNEGIGKPEPLKHEFAGFWSRRITEEHRLVYRVVENDITVLAC
RYHY

Nucleotide

• Length: 255 bp

>T197300 NZ_CP095922:c4387433-4386678 [Pseudomonas aeruginosa]
GTGAGCGAGATCTGGCGACAGTGCAAGGGTGAGCGGCATATCCGACCGCTCCAGGGGCGCCTGGTGCGGTTGGTGGAGAG
CCAGGAGCAGGTGGCGACCCTGCAATTGGTCGACACCCTGGAAGAACAGGCGTTGCTCGAGGAACTGCTCGAGTCGAGCA
AGCCGCCGGTGCCGGCGGATGCCGAGCCATTGCATTACCTGTTGAAGACCCCGTTCCGTTATCCGCCCTTGCGCTGGGGG
TCGCGGTTTGGCCGTCGCCACGAGCCAAGCCTGTTCTACGCCGCGTTGAAGCTGGAAACGGCCATGGCCGAAAGCGCGTA
TTACCGTTGCGTCCTGTGGAGTGGCATGGCGGTGCCGCCACCGAGCGGGAGGATTCTGTCCGAGCACGCTTCGTTCGAGG
CGGGCTGGAAGGTGGAGCGGGGAATCCGTCTGCAGGCGCCGCCTTTCTCCGATCACGAGGCTGCGCTGACCGACATCGCC
GACTACCGCGCTCCCCAGGAACTGGGAAGTGCCATGCGCAGCGCCGGGGTGCAGGCATTCGAATACCGTTCGGCGCGTTG
CCCGGAGCGCGGCTGCAATGTCGCCCTGTTCACGCCCGCGGCCTTCACCGAAAAGCGTCCTCGCAACCTGACGCCCTGGC
TGTGCGAAACCACGGCCGGTTACGTGGCCTTCAAGCCGGCGCATGTGCCGGGGTCGCCGAAAATCTTCTCCTGGGAGCTG
TTCCTGGTGGACGGAAAGTTGCCGCATCCGGCGTGA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9563.73 Da
• Isoelectric Point: 4.8182

>AT197300 WP_208768808.1 NZ_CP072111:937232-937486 [Corynebacterium hindlerae]
MKTISYTESRANYARVLDDVVNDREPVTITRAGHESVVMMSLDDYSSLQETAYLMRSPANARRLFDALERVKAGDVTKHE
LIED

Nucleotide

• Length: 255 bp

>AT197300 NZ_CP095922:c4387936-4387568 [Pseudomonas aeruginosa]
ATGAGCGCTCTCATCAAGGAACGTCCCAGCGCCGATGCCGTCCTGGCCAAGGCCGTCCTGGCCGCGCGCGAGCAATTGGG
GCTGACGCAGCTCGAACTGGCCGGCATCGTCGGCGTCGATCGCAGCGCCATCAGCCGCTGGAAGACCCAGGGCCTGCGGG
TGGACAGCAAGACCGGCGAGCTGGCTCTGCTGCTGGTGCGAGTCTATCGCGCACTGTATGCCCTGTTCGGCGGGCAGCAG
GAGGACATGCGCCACTTCCTGCGCACTCCCAACCATCACCTGGCGGGCGAGCCGCTGGCACTGATGGGACAGGTGCAGGG
CCTGGTTCATGTGCTGGAATACCTCGATGCGATCCGCGGCAAGGTCTGA