Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 118822..119353 Replicon chromosome
Accession NZ_CP072110
Organism Psychrosphaera ytuae strain MTZ26

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag J1N51_RS00600 Protein ID WP_208832088.1
Coordinates 119063..119353 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag J1N51_RS00595 Protein ID WP_208832087.1
Coordinates 118822..119061 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J1N51_RS00575 (J1N51_00575) 114691..114999 - 309 WP_208832083.1 hypothetical protein -
J1N51_RS00580 (J1N51_00580) 114996..115442 - 447 WP_208832084.1 hypothetical protein -
J1N51_RS00585 (J1N51_00585) 115809..117941 - 2133 WP_208832085.1 hypothetical protein -
J1N51_RS00590 (J1N51_00590) 118308..118655 - 348 WP_208832086.1 DUF3024 domain-containing protein -
J1N51_RS00595 (J1N51_00595) 118822..119061 + 240 WP_208832087.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
J1N51_RS00600 (J1N51_00600) 119063..119353 + 291 WP_208832088.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
J1N51_RS00605 (J1N51_00605) 119548..119845 - 298 Protein_120 type II toxin-antitoxin system RelE/ParE family toxin -
J1N51_RS00610 (J1N51_00610) 120089..120529 - 441 WP_208832089.1 energy transducer TonB -
J1N51_RS00615 (J1N51_00615) 120947..122107 + 1161 WP_208832090.1 tetratricopeptide repeat protein -
J1N51_RS00620 (J1N51_00620) 122139..123152 - 1014 WP_208832091.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-91)

Antitoxin

Antitoxin ParD

(1-78)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11468.38 Da        Isoelectric Point: 10.1850

>T197297 WP_208832088.1 NZ_CP072110:119063-119353 [Psychrosphaera ytuae]
MKFHLSKKVHSDLMKIGRYTQLNWGQEQRNNYLKLLDSAFHQIAEKPELGYVCDYIREGYRKRPQGSHVIYYKVFGKEEV
VIIRVLHKSMDVKRAL

Download         Length: 291 bp

>T197297 NZ_CP095922:c141786-141505 [Pseudomonas aeruginosa]
ATGAGCCTGAAGTGGACCCGCAAAGCGGCCGCCGACCTGGACGCCATCTACGACCATTACGTCGTGCTGATCGGCCCGGA
AAAAGCTCTGAAAGCCGTTCAGGACATCGTCGAGCAGGTGAAACCGCTGCAGCAGGTAGCCAACCAGGGGGCAGGGCGGC
CCAGCGAGGTGCCAGGCGTACGCACCCTGACCCTGGAGCGCTGGCCGTTCAGCGCCCCGTTTCGGGTTAAAGGCAAGGAA
ATCCAGATTTTGCGCATCGACAGGGTCGAAATTACCCCCTGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8837.69 Da        Isoelectric Point: 4.2942

>AT197297 WP_208832087.1 NZ_CP072110:118822-119061 [Psychrosphaera ytuae]
MAKNTSVTLGEHFDSFISQQLESGRYGSASEVIRAGLRALEDQELKMNNLRNMLIEGENSGVADYSYDSLLNDLDKENH

Download         Length: 240 bp

>AT197297 NZ_CP095922:c142010-141783 [Pseudomonas aeruginosa]
ATGAGCACCGTAGTCTCGTTCCGCGCCGATGACGCCCTGGTCGCGGCCCTCGACGAACTGGCCCGCGCCACCCACCGCGA
CCGCCCCTACCACCTGCGGCAGGCGCTCGCGCAGTACCTGGAAAGGCAGCAGTGGCAGGTCGCTGCCATCGATGAAGGCT
TGGCCGATGCCAATGCCGGTCGCCTGCTGGAACACACCGAGATCGAGAAGCGCTGGGGGCTGCAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References