Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/PHD-RelE
Location 2139605..2140125 Replicon chromosome
Accession NZ_CP071974
Organism Trueperella pecoris strain 15IMD0307

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag J4179_RS09685 Protein ID WP_208585030.1
Coordinates 2139865..2140125 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag J4179_RS09680 Protein ID WP_193326696.1
Coordinates 2139605..2139868 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J4179_RS09670 (J4179_09665) 2137634..2138158 + 525 WP_197551144.1 lipocalin family protein -
J4179_RS09675 (J4179_09670) 2138241..2139509 - 1269 WP_246462308.1 hypothetical protein -
J4179_RS09680 (J4179_09675) 2139605..2139868 + 264 WP_193326696.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
J4179_RS09685 (J4179_09680) 2139865..2140125 + 261 WP_208585030.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
J4179_RS09690 (J4179_09685) 2140130..2142790 - 2661 WP_246462309.1 ATP-dependent helicase HrpB -
J4179_RS09695 (J4179_09690) 2142790..2143410 - 621 WP_197551145.1 TetR/AcrR family transcriptional regulator -
J4179_RS09700 (J4179_09695) 2143532..2144209 - 678 WP_197551146.1 TrkA family potassium uptake protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(7-71)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 9985.53 Da        Isoelectric Point: 10.5719

>T197207 WP_208585030.1 NZ_CP071974:2139865-2140125 [Trueperella pecoris]
VSYRVELTTAAARQIKKLPHEARGRILDALEKLADDPRPRGAKKLVGEQNAWRIRLGDYRIIYDIFDDILTVTIVRAGHR
REIYRS

Download         Length: 261 bp

>T197207 NZ_CP095776:c4947650-4946733 [Klebsiella pneumoniae]
ATGGATATACAGGCGCCTTATTATCGGCAGGTTGCTCTGCTAATGCAGGTTTTACCCTATGTTGCTGTCGAACGGGAATT
TGCGCTGAAAGGTGGCACTGCCATCAATCTCTTTATCCGCGATTTCCCTCGATTATCGGTGGATATCGACCTCGCCTGGG
TGCCCCTGGAAAGCAGAGCCATCGCTTTACCTCATATACGGGATGCGCTTGCACGTATTGCCGCCAATCTGCAACAACAG
GCAGGTATGAGCGCTGTATTACAAGCTAATCGTTCAGATGAGATGCGTGTCATTGTTACTACCGATAGCGCGCAAATAAA
GATAGAGGTTTCACCGGTCGCCCGGGGAACATTATATCCACCACAGGAGCGAGAAGTGGTGGGGGCGGTAGAGGACGTTT
TTGGCTATGCCAGCCTTCCAGTGGTTTCGTTGCCTGACCTCTACGGTGGAAAATTATGCGCGGCGCTGGATCGCCAGCAT
CCCAGAGATTTTTATGACGTGAAATTACTTCTTGATGCGCAGGAGCTTGACCGTCCCATTTTCAATGGGTTTATCGTGTA
TTTACTGAGCCATAATCGGCCTCTGGCTGAAGTGCTGAATCCTCGCTGGAAAGATATTGCTGAACCTTTTTACCGTGAAT
TCAGCGGGATGACATTTGAGACGATAGCCCTGGAGGAACTGACAGCAGTCCCCAACAGGATGATTGCTGCGTTAAAATCC
TGTTTCACACAACAGGATGTCGATTTTTTACTGTCATTTAAACGAGGCGAACCAGACTGGCGTTTAGCGCCGGAAATGCG
TATTCAGGATTTGCCTGCCGTGCAGTGGAAATTGCGCAATATTCATCAGATGCCAGCGATAAAACGCGCTGAGTCATTAG
ATAAACTGGAAAAGGTGCTGGCCGAGTGGCGCAGTTAG

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9524.68 Da        Isoelectric Point: 4.6412

>AT197207 WP_193326696.1 NZ_CP071974:2139605-2139868 [Trueperella pecoris]
MNTITSEVSTRELRSQLSDVLGRAMYAGERIGVTRHGKLAAVVVSVADLEALEEFEMAQDVAAYRAARAEDDGGRVSLDE
LRRTLTQ

Download         Length: 264 bp

>AT197207 NZ_CP095776:c4948414-4947656 [Klebsiella pneumoniae]
ATGGCAACAAAATTAAACTGGCTGCTGCAAAACAGCGCTCCCGGAGATGTGATCCTTCAGTCCTGGTTAAGCCAGCATGC
CATCTCTCCCTCTCTGTCCTTTAAATACGCGCAAAGTGGCTGGTTAAAAAAAAGAGGCAACGGCGTATATGCGCGTGCGG
GACGTGAGCCGGAGTGGAACGATGCATTAGCATGTTTGCAAAATCAGCTTGCCGCTCCGGTGTATGTTGCGGGGCTCAGT
AGCTTAGTCTGGCAGGGCCGTTCACACTATCTACAGCTAAAACAAAACCAGTGCTGGCTTAGTGTGGAAAATAAAGCGCT
GCTGCCGAAATGGTTCAGGGAATTCCCGGGTGTGGAGTGGATAGTCATATCGGGGAAAAAACTGCCGGTGCTGGATGATA
GATACCGTGTAACGCTTGATATAAAAGGGAAAAAACTCATCGGCAGTGCGCCAGAACTGGCTGCTTACGAGTTGCTGAGC
GCGGTGCCGGGGACCCTCTCATTTAACCACGCTGCAGAGCTTTTCCAGGGGCTGGTTAATCTTAATCCTCGTAAAGTAGA
GTATCTTCTTTCCGTCAGCCAGTCCGTGCAGGCCAAGCGTTTGTATCTCTTCTTCGCCAGTTTTTACGAGCATGGCTGGC
TCAAACGAATCGATAGCCAAAAAATCGATCTGGGAGCGGGCAAGCGGCAAATCGTGGAAAATGGAAAGTTCAATGCTCAA
TACCAAATCACAGTGCCTGAACGCTTTCAAAAGGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References