Detailed information of TA system TA197186

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): pmenTA/darT(toxin)
• Location: 3415650..3417370
• Replicon: chromosome
• Accession: NZ_CP071955
• Organism: Xanthomonas fragariae strain YL19

Toxin (Protein)

• Gene name: pmenT
• Uniprot ID: -
• Locus tag: J5I97_RS16250
• Protein ID: WP_208587619.1
• Coordinates: 3415650..3416300 (+)
• Length: 217 a.a.

Antitoxin (Protein)

• Gene name: pmenA
• Uniprot ID: -
• Locus tag: J5I97_RS16255
• Protein ID: WP_238135557.1
• Coordinates: 3416339..3417370 (+)
• Length: 344 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
J5I97_RS16225	3411030..3411701	+	672	WP_208587614.1	methyltransferase	-
J5I97_RS16230	3411806..3413152	-	1347	WP_208587615.1	IS701 family transposase	-
J5I97_RS16240	3413567..3414358	-	792	WP_208587616.1	polysaccharide deacetylase family protein	-
J5I97_RS16245	3414404..3415330	+	927	WP_208587617.1	Grx4 family monothiol glutaredoxin	-
J5I97_RS16250	3415650..3416300	+	651	WP_208587619.1	DUF4433 domain-containing protein	Toxin
J5I97_RS16255	3416339..3417370	+	1032	WP_238135557.1	macro domain-containing protein	Antitoxin
J5I97_RS16260	3417477..3418037	-	561	WP_208587621.1	DUF924 family protein	-
J5I97_RS16265	3418122..3418430	+	309	Protein_3039	amidohydrolase	-
J5I97_RS16270	3418608..3419423	-	816	WP_208587622.1	cellulase	-
J5I97_RS16275	3419689..3419929	+	241	Protein_3041	DegV family protein	-
J5I97_RS16280	3419995..3420333	+	339	WP_208587623.1	hypothetical protein	-
J5I97_RS16285	3420387..3421217	-	831	WP_208587624.1	S-formylglutathione hydrolase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• ssDNA thymidine ADP-ribosyltransferase, DarT (16-216)

Antitoxin

• Macro domain (5-117)

Sequences

Toxin

Protein

• Length: 217 a.a.
• Molecular weight: 24926.47 Da
• Isoelectric Point: 8.4986

>T197186 WP_208587619.1 NZ_CP071955:3415650-3416300 [Xanthomonas fragariae]
MSRRYPNLNPDKALIWRIVHRDNLPWIMDNGLHCGNGGVQSPGWVSIGNPELIAKRANHPVPLAPGGFLNDYVPFYFTPF
SPMLRNIHTGWGGIQRRSNEEIVILVSSLHHVAARGWLFLFTDSHADYQLTTFHSDLANLCKIDWPLLQARDFRRDQEDP
AKFERYQAEALVHRHLPIDGLRGIVGYTDDMKLSIERQLKARNLTLPVHARPEWYF

Nucleotide

• Length: 651 bp

>T197186 NZ_CP095770:c5861382-5861200 [Pseudomonas aeruginosa]
ATGCGGAGTAGGGAAGTGATTGATTTGCTGTTGGAGGATGGCTGGTATGAAGTGGCGGTGAAAGGTAGCCACCACCAGTT
CAAACATCCTTCAAAGCCTGGAAAGGTGACGGTTCAACATCCGTCCTCGACGATACCGAAAGGAACCCTGAACAACATAC
TGAAACAAGCCGGCCTCAAGTGA

Antitoxin

Protein

• Length: 344 a.a.
• Molecular weight: 38126.74 Da
• Isoelectric Point: 5.3103

>AT197186 WP_238135557.1 NZ_CP071955:3416339-3417370 [Xanthomonas fragariae]
VEALVNTVNTVGVMGKGIALMFKERFNENFLRYAAACKAKQVRTGKVFVTEANELDGPRWIINFPTKQHWRGDSRIEWIT
EGLQDLRLFLIENKVGSIAIPPLGAGNGGLDWADVRPLIEESLAGLDTDIFVFEPTLKYQNVAKRSGVETLTPARALIAE
LVRRYWVLGVECSLLEIQKLAWFLERNIERAGLPTLDLRFAPNKYGPYADRLRHLLDGLDGSYLHCDKRIGDADPIDVIW
FDDARKSVVHAYLKSEAKQYAPALEATAALIDGFETPFGMELLATVDWLIAQGGVCPQVADMREGIRNWPGGADAAVRKD
RLFDDRALGIALERLTSSASAVT

Nucleotide

• Length: 1032 bp

>AT197186 NZ_CP095770:c5861172-5860768 [Pseudomonas aeruginosa]
ATGAAATTCCCCGTGGTGTTACACAAAGACCCTGATTCTGACTATGGCGTGACTGTGCCCGATGTGCCGGGTTGCTTCTC
TGCCGGCGCTACGGTGTCCGAGGCCCTGGCCAATGTAGAAGAGGCGCTGGCCTTGCACTTCGAAGGCTTGGTTACGGACG
GCGAAGAGCTACCCCAGCCGCAGGACGTTGACGCCCATATGAAGAATCCGGACTTCGAAGGTGGCGTATGGGCGGTGGTT
GACTTCGACGTGACCCCGTACCTGGGCAAGGCCGTACGCTTTAATGCGACGCTCCCGGAACACCTTCTGCAGCGGATCGA
TGAGCGCGTGAAGGTGGATAAGCGCTATCAGTCTCGGTCGGGCTTTCTGGCAACAGCGGCGATGCGCGAACTGTCAGTGG
CGTGA