Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 222046..222593 Replicon chromosome
Accession NZ_CP071953
Organism Candidatus Kaistella beijingensis strain PM-38

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag J4771_RS00955 Protein ID WP_224135621.1
Coordinates 222294..222593 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag J4771_RS00950 Protein ID WP_224135620.1
Coordinates 222046..222297 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J4771_RS00935 (J4771_00930) 217363..218085 + 723 WP_224135617.1 hypothetical protein -
J4771_RS00940 (J4771_00935) 218960..219670 + 711 WP_224135618.1 Ail/Lom family outer membrane beta-barrel protein -
J4771_RS00945 (J4771_00940) 220470..221822 + 1353 WP_224135619.1 hypothetical protein -
J4771_RS00950 (J4771_00945) 222046..222297 + 252 WP_224135620.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
J4771_RS00955 (J4771_00950) 222294..222593 + 300 WP_224135621.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
J4771_RS00960 (J4771_00955) 222890..223126 + 237 WP_224135622.1 hypothetical protein -
J4771_RS00965 223126..223320 + 195 Protein_186 DnaJ domain-containing protein -
J4771_RS00970 (J4771_00965) 223759..224421 + 663 WP_224135623.1 hypothetical protein -
J4771_RS00975 (J4771_00970) 224521..225849 + 1329 WP_224135624.1 ATP-binding protein -
J4771_RS00980 (J4771_00975) 225839..226537 + 699 WP_224135625.1 RloB family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 193532..234321 40789


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-92)

Antitoxin

Antitoxin ParD

(1-81)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 12075.73 Da        Isoelectric Point: 4.7552

>T197152 WP_224135621.1 NZ_CP071953:222294-222593 [Candidatus Kaistella beijingensis]
MKCKISKEAEKDLEKIWLYTFETWSLEQADYYYDLLMDEIEYLAENPKNGMDFSQIRKGYFRSRVKSHFIFYRISTKSDE
IEIIRILHQQMDIDSQLSE

Download         Length: 300 bp

>T197152 NZ_CP095762:807503-807913 [Klebsiella pneumoniae]
GTGGTCCTGTGGCAATCTGATCTCCGTATCTCCTGGCGCGCGCAGTGGTTTTCCCTGCTGCTTCACGGCGTGGTGGCGGC
CCTGGTGCTGTTGGTTCCCTGGCCGCTGAGCTATACCCCGATCTGGCTGCTGCTGCTGTCGCTGGTGGTCTTCGACTGCG
TGCGCAGCCAGCGGCGGATCCATGCCCGTCGCGGGGAGATAAAACTGCTCACCGATTCCCGTCTTCGCTGGCAAAACGCC
GAATGGGAAATCCTCGGGACGCCGTGGGTTATCAATAGCGGTATGCTGCTGCGTTTGCGCCATGTCGATACCCGGCGCGG
ACAGCATCTTTGGCTGGCGGCGGACAGCATGGACGCCGGAGAGTGGCGCGATCTGCGCCGGCTGGTGCTGCAAAAACCGG
CGCAGGAGTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9531.87 Da        Isoelectric Point: 10.0990

>AT197152 WP_224135620.1 NZ_CP071953:222046-222297 [Candidatus Kaistella beijingensis]
MAKNTSILLGDYFDNFISQQIQTGKFSSASEVVRAALRMFEHEESKKTQLINELKKGEKSGFVKDFDRKNFLNGLHKKYA
AEK

Download         Length: 252 bp

>AT197152 NZ_CP095762:807256-807522 [Klebsiella pneumoniae]
ATGGACATTAACAATAAAGCACGTATCCACTGGGCATGCCGCCGCGGGATGCGCGAACTCGACATCTCCATCATGCCGTT
CTTTGAGTATGAGTACGATACCCTCAGCGACGCTGACAAACAGCTGTTCATTCGCCTGCTGGAAAATGACGATCCGGATC
TGTTCAACTGGCTGATGAACCACGGCAAACCGGCCGATGCGGAGCTGCAGCGGATGGTAACCTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References