Detailed information of TA system TA197125

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 4877884..4878440
• Replicon: chromosome
• Accession: NZ_CP071891
• Organism: Xanthomonas oryzae pv. oryzae strain T7133

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: J4Q40_RS22880
• Protein ID: WP_229001948.1
• Coordinates: 4878189..4878440 (+)
• Length: 84 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A854CIX2
• Locus tag: J4Q40_RS22875
• Protein ID: WP_011408759.1
• Coordinates: 4877884..4878162 (+)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
J4Q40_RS22845	4873001..4873558	-	558	WP_011259349.1	DNA-3-methyladenine glycosylase	-
J4Q40_RS22850	4873708..4874673	-	966	WP_109181928.1	IS1595-like element ISXo5 family transposase	-
J4Q40_RS22855	4875254..4876438	+	1185	WP_011408397.1	IS256-like element IS1113 family transposase	-
J4Q40_RS22865	4877344..4877688	+	345	WP_199285675.1	hypothetical protein	-
J4Q40_RS22875	4877884..4878162	+	279	WP_011408759.1	CopG family ribbon-helix-helix protein	Antitoxin
J4Q40_RS22880	4878189..4878440	+	252	WP_229001948.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
J4Q40_RS22885	4878517..4878771	+	255	WP_198912806.1	hypothetical protein	-
J4Q40_RS24125	4878764..4878898	+	135	WP_011051575.1	hypothetical protein	-
J4Q40_RS22890	4878967..4879221	+	255	WP_223293127.1	hypothetical protein	-
J4Q40_RS24025	4879438..4879557	+	120	Protein_4389	IS3 family transposase	-
J4Q40_RS24130	4879526..4879654	+	129	WP_012444694.1	hypothetical protein	-
J4Q40_RS22900	4880085..4880486	-	402	WP_011259345.1	H-NS family nucleoid-associated regulatory protein	-
J4Q40_RS22905	4880708..4880884	+	177	Protein_4392	DUF3606 domain-containing protein	-
J4Q40_RS22915	4881166..4881503	+	338	Protein_4393	ATP-dependent DNA ligase	-
J4Q40_RS22920	4881579..4882670	-	1092	WP_041182166.1	ribonuclease D	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-81)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 84 a.a.
• Molecular weight: 9603.92 Da
• Isoelectric Point: 9.9718

>T197125 WP_229001948.1 NZ_CP071891:4878189-4878440 [Xanthomonas oryzae pv. oryzae]
MLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDGDTVTILAVRHQKE
AGY

Nucleotide

• Length: 252 bp

>T197125 NZ_CP095736:1922935-1923186 [Bacillus subtilis]
ATGAACTTCTCCTTTAGTTCCTACCCATATTATAACATGATCAAGCACATTGCAAACATGAAACGATTCTCATTATGGTT
TACCCATATCACTTTCATTGGCTTATTCTTAATGTTTCAACTCATTAAGGATTACTTCAGCAGCGAAGCACAAACACTAA
TCAATATAATATTCATAGTCACATGTATCATTGCCATATTGTTATGGATTATCTATTTTGTATTCCTTAAACTAAGAAAC
AAGTCACACTAA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10826.11 Da
• Isoelectric Point: 4.9736

>AT197125 WP_011408759.1 NZ_CP071891:4877884-4878162 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Nucleotide

• Length: 279 bp

>AT197125 NZ_CP095736:c1922957-1922857 [Bacillus subtilis]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATATGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Structures

Antitoxin

• AlphaFold DB: A0A854CIX2