Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 4375057..4376576 Replicon chromosome
Accession NZ_CP071891
Organism Xanthomonas oryzae pv. oryzae strain T7133

Toxin (Protein)


Gene name rlegT Uniprot ID A0A0K0GMB6
Locus tag J4Q40_RS20670 Protein ID WP_011259680.1
Coordinates 4375653..4376576 (+) Length 308 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A854CLN1
Locus tag J4Q40_RS20665 Protein ID WP_011409027.1
Coordinates 4375057..4375656 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J4Q40_RS20630 4370739..4371275 - 537 WP_011409032.1 lipocalin family protein -
J4Q40_RS23915 4371545..4372012 - 468 WP_181718264.1 hypothetical protein -
J4Q40_RS23920 4371993..4372283 - 291 WP_011409031.1 hypothetical protein -
J4Q40_RS20650 4372782..4373813 + 1032 WP_042465093.1 IS630 family transposase -
J4Q40_RS20655 4373795..4374370 - 576 WP_011409029.1 BrxE family protein -
J4Q40_RS20660 4374402..4374692 - 291 WP_228329665.1 FaeA/PapI family transcriptional regulator -
J4Q40_RS20665 4375057..4375656 + 600 WP_011409027.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
J4Q40_RS20670 4375653..4376576 + 924 WP_011259680.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
J4Q40_RS23925 4376656..4377126 - 471 WP_228329666.1 helix-turn-helix domain-containing protein -
J4Q40_RS20685 4377592..4377834 + 243 WP_011409025.1 hypothetical protein -
J4Q40_RS20690 4378286..4379251 - 966 Protein_3972 IS1595-like element ISXo5 family transposase -
J4Q40_RS20695 4379346..4379834 + 489 WP_011409022.1 hypothetical protein -
J4Q40_RS20700 4379851..4380383 - 533 Protein_3974 methyltransferase domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(41-269)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(7-52)


Sequences

Toxin        


Download         Length: 308 a.a.        Molecular weight: 34114.16 Da        Isoelectric Point: 5.4588

>T197124 WP_011259680.1 NZ_CP071891:4375653-4376576 [Xanthomonas oryzae pv. oryzae]
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA

Download         Length: 924 bp

>T197124 NZ_CP095736:1922740-1922916 [Bacillus subtilis]
GTGCTTGAGAAAGTGGGTATCATAGTTGCTTTCCTCATATCTTTAACGGTTCTTACAATCAACAGTCTAACAATAGTTGA
GAAGGTAAGAAACCTAAAGAATGGGACAAGCAAAAAGAAAAAGCGTATACGCAAGCGGCTCCGACCAAAGAGACAACGCC
AACATATACGCCGATGA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22037.74 Da        Isoelectric Point: 10.1240

>AT197124 WP_011409027.1 NZ_CP071891:4375057-4375656 [Xanthomonas oryzae pv. oryzae]
MDTTVDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA

Download         Length: 600 bp

>AT197124 NZ_CP095736:c1922957-1922857 [Bacillus subtilis]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATATGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K0GMB6

Antitoxin

Source ID Structure
AlphaFold DB A0A854CLN1

References