Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 1728376..1729121 Replicon chromosome
Accession NZ_CP071891
Organism Xanthomonas oryzae pv. oryzae strain T7133

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag J4Q40_RS08025 Protein ID WP_199285672.1
Coordinates 1728376..1728705 (+) Length 110 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag J4Q40_RS08030 Protein ID WP_011407754.1
Coordinates 1728702..1729121 (+) Length 140 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J4Q40_RS07995 1723507..1724178 + 672 WP_011407759.1 class I SAM-dependent methyltransferase -
J4Q40_RS08005 1724480..1725271 - 792 WP_011407758.1 polysaccharide deacetylase family protein -
J4Q40_RS08010 1725317..1726243 + 927 WP_011257932.1 Grx4 family monothiol glutaredoxin -
J4Q40_RS08015 1726575..1726910 + 336 WP_011407757.1 DarT ssDNA thymidine ADP-ribosyltransferase family protein -
J4Q40_RS08020 1726954..1728273 - 1320 WP_011407756.1 IS701 family transposase -
J4Q40_RS08025 1728376..1728705 + 330 WP_199285672.1 DUF4433 domain-containing protein Toxin
J4Q40_RS08030 1728702..1729121 + 420 WP_011407754.1 macro domain-containing protein Antitoxin
J4Q40_RS08035 1729173..1730141 + 969 WP_011258802.1 IS5-like element ISXo1 family transposase -
J4Q40_RS08040 1730276..1730932 + 657 WP_075246166.1 phosphate phosphatase -
J4Q40_RS08045 1730970..1732205 - 1236 WP_011257570.1 ISL3-like element ISXoo13 family transposase -
J4Q40_RS08050 1732507..1732833 + 327 Protein_1562 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside IScluster/Tn - - 1726954..1732205 5251


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(3-108)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 13145.86 Da        Isoelectric Point: 7.1160

>T197121 WP_199285672.1 NZ_CP071891:1728376-1728705 [Xanthomonas oryzae pv. oryzae]
MHHVAERRWPFLFTDSHAYCQLASFYSDLSDLDKIDWPLLQARDFRRDPDDPAKFERYQAEALIHRHLPLDGLRGIVCHT
DGLKQTIERQLQERNLKLPVHTRTDWYFR

Download         Length: 330 bp

>T197121 NZ_CP095736:532381-532731 [Bacillus subtilis]
TTGATTGTGAAACGCGGCGATGTTTATTTTGCTGATTTATCTCCTGTTGTTGGCTCAGAGCAAGGCGGGGTGCGCCCGGT
TTTAGTGATCCAAAATGACATCGGAAATCGCTTCAGCCCAACTGCTATTGTTGCAGCCATAACAGCACAAATACAGAAAG
CGAAATTACCAACCCACGTCGAAATCGATGCAAAACGCTACGGTTTTGAAAGAGATTCCGTTATTTTGCTGGAGCAAATT
CGGACGATTGACAAGCAAAGGTTAACGGATAAGATTACTCATCTGGATGATGAAATGATGGATAAGGTTGATGAAGCCTT
ACAAATCAGTTTGGCACTCATTGATTTTTAG

Antitoxin


Download         Length: 140 a.a.        Molecular weight: 15607.02 Da        Isoelectric Point: 6.4733

>AT197121 WP_011407754.1 NZ_CP071891:1728702-1729121 [Xanthomonas oryzae pv. oryzae]
MITFTQGNLLESGAEALVNTVNTVGVMGKGIALMFKERFKENFLRYAAACKDNQVRIGKIFVTEVNELDGPRWIINFPTK
QHWRGDSRIEWITEGLQDLHRFLIENKVKSIAIPPLGAGNGGLDWAEVRPLIEEVLGNL

Download         Length: 420 bp

>AT197121 NZ_CP095736:532095-532376 [Bacillus subtilis]
TTGTCTGAATCCAGCGCAAGAACCGAAATGAAAATCAGCTTGCCCGAAAACCTAGTAGCTGAATTGGATGGTGTAGCGAT
GCGGGAGAAACGAAGCAGAAACGAACTGATATCACAAGCAGTGAGAGCGTATGTCAGCGAACGAACAACTCGTCACAACC
GTGATTTGATGAGACGCGGCTATATGGAAATGGCGAAAATCAACCTGAATATTTCTTCTGAGGCTCACTTTGCGGAGTGC
GAGGCTGAAACGACAGTTGAGCGCTTAGTCAGCGGAGGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References